Conference: Drinking Water Disinfection By-Products:, Disinfection 2100, Linking Engineering, Chemistry, Toxicology and Epidemiology, 30JUL-4AUG, 2017, Mt. Holyoke College, MA

1654958 .饮用水消毒是上个世纪主要的公共卫生成就之一；然而，化学副产品（消毒副产品）的形成代表了最广泛的潜在有害化学物质的暴露之一。随着公用事业公司试验新的消毒剂组合和开发受损水域，优化病原体造成的急性风险和消毒副产物造成的慢性风险之间的平衡变得越来越具有挑战性。2017年戈登饮用水消毒副产物（DBPs）研究会议将展示来自工程、化学、毒理学、流行病学和监管政策领域的前沿研究，以应对这一挑战。2017年会议，题为消毒2100：连接工程，化学，毒理学和流行病学，以减少暴露于毒性驱动因素，同时减少病原体，将于2017年7月30日至8月4日在马萨诸塞州南哈德利的霍利奥克山学院举行。这次会议有两个主要目标。第一个目标是扩大常规饮用水厂内DBP形成的范围。前两次会议将直接讨论与病原体相关的急性风险与与dbp相关的慢性风险之间的平衡。第一次会议将评估消毒剂与病原体的反应，认识到负责病原体杀死的生物分子转化是dbp。第二部分将讨论分配系统中微生物生长和dbp之间的权衡，这是饮用水系统中评估最少的部门。第六部分将重点讨论废水回收中的dbp，特别是哪些dbp对毒性贡献最大以及如何控制它们。会议还将包括dbp的新领域，包括在食品加工过程中形成dbp。第二个目标是寻求DBP问题的解决方案。这次会议的一个主要优势是它汇集了工程师、化学家、毒理学家、流行病学家和监管机构，他们是解决这一问题的关键参与者。以前的会议得出的结论是，没有可行的方法来控制病原体而不产生dbp，因此挑战是实现最佳平衡，使dbp驱动风险最小化。会议将把化学和毒理学联系起来，以确定这些毒性驱动因素。第8次会议将由化学家、暴露专家和流行病学家讨论如何设计理想的流行病学研究，以提供将暴露与人类健康风险联系起来的证据。第9部分将以介绍和讨论如何设计水处理系统以最大限度地减少毒性驱动因素，包括荷兰公用事业公司关于如何避免在饮用水分配系统中使用消毒剂的介绍结束。随着美国公用事业公司目前修改其消毒方案并利用受损的供水，工程、化学、毒理学、流行病学和监管政策方面的专家讨论这些新做法导致的病原体和dbp之间的风险平衡是很重要的。为期4.5天的戈登研究会议形式，有很长的讨论时间和充足的非正式讨论和社会互动，特别适合促进所需的多学科方法。会议之前将有一个为期1.5天的戈登研究研讨会（GRS），由早期职业科学家组织。GRS的特色是研究生和博士后研究员的演讲，以及由知名学术、政府和工业科学家组成的职业指导小组。戈登会议通常被认为是各自领域最杰出的会议。通过突出新兴研究人员作为GRC的演讲者，并通过GRS鼓励年轻科学家的发展，本次会议将有助于为下一代科学家的多学科研究奠定坚实的基础。

1654958MitchDisinfection of drinking water is one of the major public health achievements of the last century; however, but the chemical byproducts (disinfection by-products) that form represent one of the most widespread exposures to potentially harmful chemicals. Optimizing the balance between the acute risk posed by pathogens and the chronic risk posed by disinfection by-products is becoming more challenging as utilities experiment with new disinfectant combinations and exploit impaired waters. The 2017 Gordon Research Conference on Drinking Water Disinfection By-Products (DBPs) will present cutting-edge research to address this challenge from the fields of engineering, chemistry, toxicology, epidemiology and regulatory policy. The 2017 meeting, entitled Disinfection 2100: Linking Engineering, Chemistry, Toxicology, and Epidemiology to Reduce Exposure to Toxicity Drivers While Curtailing Pathogens, will take place from July 30-August 4, 2017 at Mt. Holyoke College in South Hadley, MA.The conference has two main goals. The first goal is to broaden the scope beyond DBP formation within conventional drinking water plants. The first two sessions will directly address the balance between the acute risk associated with pathogens and the chronic risk linked to DBPs. The first session will evaluate disinfectant reactions with pathogens, recognizing that the biomolecular transformations responsible for pathogen kill are DBPs. The second session will cover tradeoffs between microbial growth and DBPs within distribution systems, the least evaluated sector of drinking water systems. The sixth section will focus on DBPs in wastewater recycling, particularly which DBPs contribute most to toxicity and how to control them. The conference will also include new arenas for DBPs, including the formation of DBPs during food processing. The second goal is to move towards a solution to the DBP problem. A major strength of this conference is that it brings together engineers, chemists, toxicologists, epidemiologists and regulators, the key players for addressing this problem. Previous conferences have concluded that there is no feasible way to control pathogens without producing DBPs, so the challenge is to achieve the best balance that minimizes exposure to the DBPs driving risk. Sessions will link chemistry and toxicology to identify these toxicity drivers. Session 8 will feature discussions among chemists, exposure experts and epidemiologists about how the ideal epidemiology study should be designed to provide the evidence to link exposure to human health risks. Session 9 will conclude with presentations and a discussion regarding how to design water treatment systems that minimize toxicity drivers, including a presentation from a Dutch utility on how to avoid the use of disinfectants in drinking water distribution systems. With US utilities currently modifying their disinfection schemes and exploiting impaired water supplies, it is important for experts in engineering, chemistry, toxicology, epidemiology and regulatory policy to discuss the risk balance between pathogens and DBPs resulting from these new practices. The 4.5-day Gordon Research Conference format, with lengthy discussion periods and ample provision for informal discussions and social interactions, is particularly suited to promoting the needed multidisciplinary approach. The Conference will be preceded by a 1.5-day Gordon Research Seminar (GRS), organized by early career scientists. The GRS will feature presentations by graduate students and postdoctoral fellows, and a career mentoring panel by established academic, government and industrial scientists. Gordon Conferences are often considered the pre-eminent conferences in their fields. By highlighting emerging researchers as presenters in the GRC and encouraging the development of young scientists through the GRS, this conference will help lay a solid foundation for multidisciplinary research for the next generation of scientists.