SBIR Phase II: Biomanufacturing Red Natural Food Dye

SBIR 第二阶段：生物制造红色天然食品染料

• 批准号: 1659039
• 负责人: Jordan Wood
• 金额: $ 75万
• 依托单位: RedLeaf Biologics Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-01 至 2023-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1659039&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Biomanufacturing; Red

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to develop natural alternatives to synthetic chemicals that are used to impart color to food, medicine, and cosmetics. Negative health impacts of some high volume synthetic colorants are driving demand for natural and safe colorants that are obtained from biological sources. This project will advance the commercial feasibility of a class of naturally occurring pigments that have properties of color, functionality, stability, and safety that make them attractive as food colorants. Based on six years of prior university research, a potentially suitable botanical source of a red pigment has been identified. The goal of this project is to develop a commercial process to produce the pigment from this botanical source. The pigment will be tested as a replacement for a synthetic red pigment that has been widely used as a food additive. The goal is to provide a natural alternative to reduce the health risks associated with artificial colorants.This SBIR Phase II project proposes to develop a naturally occurring red pigment from a plant source as an alternative food color additive. Phase I demonstrated that the red pigment could be extracted at small-scale and performed well in food applications. The goal of this Phase II project is to scale up commercial processes for extraction and purification of this red pigment, and to conduct further performance testing. The pigment, which previously has not been available in commercial quantities, will be produced from a selected variety of a major crop species. The goal is to develop processes to scale pigment production under conditions that will validate a commercial scale. This will include the integration of mechanical separation, food grade extraction, and various commercially-available clarification systems. The products will be tested for performance characteristics and consistency of quality during scale up by examining thermal, pH, and light stability in a range of probable food and other applications. In addition, yield produced will be evaluated to validate economic competitiveness.

这个小型企业创新研究(SBIR)第二阶段项目的更广泛的影响/商业潜力将是开发用于赋予食品、药品和化妆品颜色的合成化学品的天然替代品。一些大量合成着色剂对健康的负面影响正在推动对来自生物来源的天然和安全着色剂的需求。该项目将提高一类天然色素的商业可行性，这种色素具有颜色、功能性、稳定性和安全性，使其作为食品着色剂具有吸引力。基于之前六年的大学研究，已经确定了一种潜在的适合植物的红色素来源。该项目的目标是开发一种从这种植物来源生产这种色素的商业工艺。这种色素将作为一种被广泛用作食品添加剂的合成红色素的替代品进行测试。其目标是提供一种天然替代品，以减少与人造着色剂相关的健康风险。这项SBIR第二阶段项目建议从植物来源开发一种天然产生的红色色素，作为替代食品着色剂。阶段I表明，红色素可以小规模提取，并在食品应用中表现良好。这个第二阶段项目的目标是扩大这种红色色素的提取和纯化的商业流程，并进行进一步的性能测试。这种色素以前没有商业批量供应，将从一种主要作物品种中精选出。其目标是开发工艺，在验证商业规模的条件下实现颜料生产的规模化。这将包括机械分离、食品级提取和各种商业可用的澄清系统的集成。这些产品将在放大过程中通过检查一系列可能的食品和其他应用中的热、pH和光稳定性来测试产品的性能特征和质量一致性。此外，还将对所产生的产量进行评估，以验证经济竞争力。