EAPSI: From Spores to Seeds: A Collaborative Investigation of Plant Genetics

EAPSI：从孢子到种子：植物遗传学的合作研究

• 批准号: 1713824
• 负责人: Daniel Marchant
• 金额: $ 0.54万
• 依托单位: Marchant Daniel B
• 依托单位国家: 美国
• 项目类别: Fellowship Award
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1713824&HistoricalAwards=false
• 关键词: EAPSI; Spores; Seeds; Collaborative; Investigation

Certain genes are critical for the proper growth and development of organisms. As such, changes in these genes can have large effects on the overall evolution of groups of species. The MADS-box genes are one such family of genes, which control a sizeable portion of plant development and have been found to underlie major changes in plant evolution. Through this fellowship, the awardee will work with the distinguished plant biologist Dr. Zhong-Hua Chen at Western Sydney University in New South Wales, Australia to study the MADS-box genes in ferns compared to flowering plants, which include many well-studied crops. This study will provide new insights into the ancestral MADS-box genes and the changes that have occurred in this group of genes throughout the evolutionary history of plants.Investigations of the MADS-box gene family have been a key facet of plant evolution research for nearly three decades due to their major role in development and putative role in the massive diversification of flowering plants. While the genomics era has allowed the rapid identification of putative MADS-box genes in a wide diversity of plant species, the verification, localization, and activity patterns of these genes are generally lacking in all but a few model flowering plants. In addition, the absence of a published reference genome in ferns, sister group to seed plants, has left an egregious gap in our understanding of MADS-box evolution across all of land plants. By collaborating with Dr. Zhong-Hua Chen, the awardee will use functional genetics to verify, localize, and quantify the putative MADS-box genes throughout the life cycle of the model fern, Ceratopteris richardii, the first study of this kind for a non-seed plant. These results will complement the awardee's broad genomic and transcriptomic analyses and elucidate the evolution of the MADS-box gene family across ferns, seed plants, and all of land plants.This award, under the East Asia and Pacific Summer Institutes program, supports summer research by a US graduate student and is jointly funded by NSF and the Australian Academy of Science.

某些基因对于生物的适当生长和发育至关重要。因此，这些基因的变化可能会对物种群体的总体演变产生很大影响。 MADS-box基因就是这样的基因家族，它控制着植物发育的相当一部分，并且被发现是植物进化的重大变化的基础。通过这项奖学金，获奖者将与杰出的植物生物学家在澳大利亚新南威尔士州西悉尼大学的乔阿·陈博士合作，研究蕨类植物的Mads-box基因，与开花植物相比，其中包括许多研究丰富的农作物。这项研究将为植物的整个进化史中对祖先的MADS-box基因以及在这组基因中发生的变化提供新的见解。由于它们在开发和开花植物的大规模多样化中的主要作用，Mads-box基因家族对植物进化研究的关键作用一直是植物进化研究的关键方面。尽管基因组时代允许在广泛的植物物种中快速识别推定的疯狂盒基因，但除了一些模型开花植物外，通常都缺乏这些基因的验证，定位和活性模式。此外，在蕨类植物的姐妹群中，缺乏蕨类植物中发表的参考基因组，在我们对所有土地植物中的疯狂盒进化的理解中留下了严重的差距。通过与钟河博士合作，获奖者将在模型蕨类植物的整个生命周期，Ceratopteris Richardii中使用功能遗传学来验证，本地化和量化假定的MADS-Box基因，这是对这种非种子植物的首次研究。这些结果将补充获奖者的广泛基因组和转录组分析，并阐明跨蕨类植物，种子植物和所有土地植物的Mads-Box基因家族的演变。该奖项，根据东亚和太平洋夏季研究所计划，该奖项支持美国研究生的夏季研究，并由NSF和NSF和澳大利亚科学学院共同资助。