SBIR Phase I: Porous Cyclodextrin Polymers: A Sustainable and Highly Effective Platform for Water Treatment

SBIR 第一阶段：多孔环糊精聚合物：可持续且高效的水处理平台

• 批准号: 1721809
• 负责人: Gokhan Barin
• 金额: $ 22.5万
• 依托单位: CycloPure, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1721809&HistoricalAwards=false
• 关键词: SBIR; Phase; Porous; Cyclodextrin; Polymers

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to remove organic pollutants using newly developed adsorbent materials derived from cyclodextrins. The chemical contamination of water resources due to agricultural, industrial, and human activities is known to have adverse effects on the environment, especially aquatic ecosystems, and human health. Currently utilized adsorbents, particularly activated carbons, typically have limitations in removing micropollutants effectively at environmentally relevant concentrations, ranging from parts per trillion (ppt) to parts per billion (ppb). This project will focus on the fundamental development and manufacture of polymer adsorbents from building blocks derived from corn starch that rapidly sequester many pollutants more effectively than activated carbons. These polymers exhibit tiny pores and high surface areas, and are structurally programmable to target specific contaminants and separation challenges. Current water filtration systems found in homes, hospitals, industrial settings, and municipal wastewater treatment sites will benefit from these activities.This SBIR Phase I project will develop a sustainable materials solution to address the problem of emerging organic contaminants in water. Promising materials are derived from a cyclodextrin monomer and a crosslinker, which react to provide a rigid porous network. Materials derived from this approach remove contaminants from water more effectively than leading adsorbents, such as activated carbons. Previously, initial polymers were prepared at laboratory scales in relatively low yields. The objective of this proposal is to develop polymerization conditions that provide high yields and are amenable to large-scale manufacturing processes, while maintaining the pollutant removal performance of the polymer. This objective will require a systematic study of reaction conditions to minimize side reactions and maximize polymerization efficiency. Structural characterization using various spectroscopies and porosimetry will be used to evaluate the polymerization process as a function of the reaction conditions. The polymer's ability to bind pollutants will also ensure that improved yields still maintain performance. Determining the optimal polymerization conditions and processing protocols will be critical for validating the technical feasibility of the proposed porous cyclodextrin polymer and will also be criteria for the success of this SBIR Phase I project.

这个小企业创新研究（SBIR）项目的更广泛的影响/商业潜力是使用新开发的环糊精衍生的吸附材料去除有机污染物。众所周知，农业、工业和人类活动对水资源造成的化学污染对环境，特别是水生生态系统和人类健康产生不利影响。目前使用的吸附剂，特别是活性炭，在有效去除与环境有关的微污染物浓度（从万亿分之一（ppt）到十亿分之一（ppb））方面通常存在局限性。该项目将专注于从玉米淀粉中提取的聚合物吸附剂的基础开发和制造，这种材料可以比活性炭更有效地快速隔离许多污染物。这些聚合物具有微小的孔隙和高表面积，并且在结构上可编程，可针对特定的污染物和分离挑战。目前在家庭、医院、工业环境和城市污水处理场发现的水过滤系统将受益于这些活动。SBIR一期项目将开发一种可持续材料解决方案，以解决水中新出现的有机污染物问题。有前途的材料来源于环糊精单体和交联剂，它们反应形成刚性多孔网络。这种方法产生的材料比主要的吸附剂（如活性炭）更有效地去除水中的污染物。以前，最初的聚合物是在实验室规模上以相对较低的产量制备的。本提案的目标是开发聚合条件，提供高产量，适合大规模生产工艺，同时保持聚合物的污染物去除性能。这一目标将需要一个系统的研究反应条件，以减少副反应和最大限度地提高聚合效率。结构表征使用各种光谱和孔隙率将用于评估聚合过程作为反应条件的函数。聚合物结合污染物的能力也将确保提高产量后仍能保持性能。确定最佳聚合条件和处理方案对于验证所提议的多孔环糊精聚合物的技术可行性至关重要，也是SBIR一期项目成功的标准。