Thermodynamics of Computation in Chemical and Biological Systems to be held August 14-16, 2017 at SFI

化学和生物系统计算热力学将于 2017 年 8 月 14-16 日在 SFI 举行

• 批准号: 1741021
• 负责人: David Wolpert
• 金额: $ 5万
• 依托单位: Santa Fe Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1741021&HistoricalAwards=false
• 关键词: Thermodynamics; Computation; Chemical; Biological; Systems

The workshop "Thermodynamics of computation in chemical and biological systems" at the Santa Fe Institute (SFI) will explore the role of both thermodynamics and computation in constraining biological processes, evolution, and metabolism. The workshop will be held over two-and-a-half days investigating the connection between thermodynamics and computation in a variety of topics including: pure computer science, the statistical mechanics of computation, chemical computers, the thermodynamics and computation of organisms. A synthesis of these topics will be necessary to more fully understand the general features of the thermodynamics of computation. In particular, understanding the fundamental aspects of the computations and energetics of life explicitly requires a treatment of each of the listed topics. Several graduate students and postdocs will participate in the meeting and the presentations and discussions will further their training and provide an array of new collaborations and opportunities for them in their research. An SFI NSF REU student will be co-mentored this summer on a project focused on the thermodynamics of biological computation. In addition, two of the co-organizers will present the new ideas discussed at the workshop to both the general public and scientific community.The workshop will connect three sub-disciplines - statistical physics, computation and biological and chemical computers - to each other in an attempt to provide the field with deeper theoretical coherence and connection. In particular, there is the need to migrate computer science and statistical physics tools for use in biological and chemical computers, and in turn, to use the biological and chemical systems to inspire new theoretical questions and techniques.

圣达菲研究所的“化学和生物系统计算热力学”研讨会将探讨热力学和计算在限制生物过程、进化和新陈代谢方面的作用。研讨会将举行两天半，研究热力学和计算之间的联系，主题包括：纯计算机科学、计算的统计力学、化学计算机、热力学和生物体的计算。为了更充分地理解计算热力学的一般特征，有必要对这些主题进行综合。特别是，理解生命的计算和能量学的基本方面，显然需要对列出的每一个主题进行处理。几名研究生和博士后将参加会议，演讲和讨论将进一步培训他们，并为他们在研究方面提供一系列新的合作和机会。今年夏天，SFI NSF REU的一名学生将在一个专注于生物计算热力学的项目上得到共同指导。此外，其中两个协办机构将向公众和科学界介绍研讨会上讨论的新概念。工作坊将把统计物理、计算和生物化学计算机这三个子学科相互联系起来，试图为该领域提供更深层次的理论一致性和联系。特别是，需要将计算机科学和统计物理工具移植到生物和化学计算机中使用，并反过来利用生物和化学系统来启发新的理论问题和技术。

项目成果

Beyond Number of Bit Erasures: New Complexity Questions Raisedby Recently discovered thermodynamic costs of computation

超越位擦除次数：最近发现的计算热力学成本提出的新复杂性问题

• DOI: 10.1145/3232679.3232689
• 发表时间: 2018
• 期刊: ACM SIGACT News
• 作者: Grochow, Joshua A.;Wolpert, David H.
• 通讯作者: Wolpert, David H.