REU Site: Integration of Chemical Theory, Computation and Experiment at Duquesne University

REU 网站：杜肯大学化学理论、计算和实验的整合

• 批准号: 2244151
• 负责人: Jeffrey Evanseck
• 金额: $ 39万
• 依托单位: Duquesne University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2244151&HistoricalAwards=false
• 关键词: REU; Site; Integration; Chemical; Theory

The Research Experiences for Undergraduates (REU) site award to Duquesne University, located in Pittsburgh, PA, supports the training of 10 students for 10 weeks during the summers of 2023-2025. Funded by the Division of Chemistry, the Duquesne REU site continues to impact the professional chemistry careers and education of undergraduates and faculty from Appalachian regional institutions with limited research infrastructure and/or from underrepresented populations. To meet this challenge, Duquesne University delivers a quality research experience, with a focus on computational and theoretical chemistry, that motivates undergraduates and faculty to achieve their highest academic performance and best prepare them for scientific research and discovery. The core idea is to establish meaningful, year-round, and long-term research collaborations driven by the need for academic productivity and excellence in undergraduate training. The REU site serves national interest by promoting advances in the basic sciences, training and support of the U.S. scientific workforce, and advancing prosperity and welfare. This project focuses on strong financial and infrastructure support of research collaborations that invigorate PUI/HBC/LSAMP faculty, who in turn directly impact students and learning environments at their home institutions. Duquesne has NSF-funded resources, established research programs, proven record in student placement, and strong partnerships with local industry. REU students receive explicit training to reinforce the scientific method, scientific writing and speaking, ethics, safety, and workshops on state-of-the-art instrumentation to complement their experimental research and build invaluable skill sets. Each student has the opportunity to present their research locally, regionally, and nationally to expand their professional exposure and networking to make more informed career decisions and best prepare for graduate school. The PUI/HBC/LSAMP faculty are empowered through meaningful and productive academic collaboration to enhance their professional development. The broader impacts of this work include meaningful research experiences to attract and retain the nation’s diverse student talent pool, which has the consequence of enhancing and diversifying the U.S. workforce by adding experts in the fields of chemistry or biochemistry.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

位于宾夕法尼亚州匹兹堡的Duquesne University授予本科生（REU）现场奖的研究经验，在2023 - 2025年夏季，支持10个学生的培训10周。 Duquesne REU站点由化学司资助，继续影响来自阿巴拉契亚地区机构的本科生和教职员工的专业化学职业和教育，其研究基础设施有限和/或来自代表性不足的人群。为了应对这一挑战，杜肯大学（Duquesne University）提供了优质的研究经验，专注于计算和理论化学，激励大学生和教职员工取得最高的学业表现，并为科学研究和发现做好准备。核心思想是建立有意义的，全年且长期的研究合作，这是由学术生产力和卓越本科培训的需求所驱动的。 REU网站通过促进美国科学劳动力的基础科学，培训和支持以及促进繁荣和福利的基础科学，培训和支持，从而为国家利益提供服务。该项目着重于激发PUI/HBC/LSAMP教职员工的研究合作的强大财务和基础设施支持，后者又直接影响其家庭机构的学生和学习环境。 Duquesne拥有NSF资助的资源，已建立的研究计划，在学生安置方面有验证的记录，并与本地行业建立了牢固的合作伙伴关系。 REU学生接受明确的培训，以加强有关最先进仪器的科学方法，科学写作和说话，道德，安全和讲习班，以补充其实验研究并建立宝贵的技能。每个学生都有机会在本地，区域和全国范围内介绍他们的研究，以扩大其专业曝光和网络，以做出更明智的职业决策，并为研究生院做准备。 PUI/HBC/LSAMP教师通过有意义且富有成效的学术合作来增强其专业发展。这项工作的更广泛的影响包括有意义的研究经验，以吸引和保留全国多样化的学生人才库，其结果是通过增加化学或生物化学领域的专家来增强和多样化美国的劳动力。这项奖项反映了NSF的法定任务，反映了通过评估基金会的诚实评估，并通过基金会的范围进行了评估。

项目成果

Effect of the SARS-CoV-2 Delta-associated G15U mutation on the s2m element dimerization and its interactions with miR-1307-3p

SARS-CoV-2 Delta 相关 G15U 突变对 s2m 元件二聚化的影响及其与 miR-1307-3p 的相互作用

• DOI: 10.1261/rna.079627.123
• 发表时间: 2023
• 期刊: RNA
• 影响因子: 4.5
• 作者: Cunningham, Caylee L.;Frye, Caleb J.;Makowski, Joseph A.;Kensinger, Adam H.;Shine, Morgan;Milback, Ella J.;Lackey, Patrick E.;Evanseck, Jeffrey D.;Mihailescu, Mihaela-Rita
• 通讯作者: Mihailescu, Mihaela-Rita