REU Site: Integration of Chemical Theory, Computation and Experiment at Duquesne University

REU 网站：杜肯大学化学理论、计算和实验的整合

• 批准号: 2244151
• 负责人: Jeffrey Evanseck
• 金额: $ 39万
• 依托单位: Duquesne University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2244151&HistoricalAwards=false
• 关键词: REU; Site; Integration; Chemical; Theory

The Research Experiences for Undergraduates (REU) site award to Duquesne University, located in Pittsburgh, PA, supports the training of 10 students for 10 weeks during the summers of 2023-2025. Funded by the Division of Chemistry, the Duquesne REU site continues to impact the professional chemistry careers and education of undergraduates and faculty from Appalachian regional institutions with limited research infrastructure and/or from underrepresented populations. To meet this challenge, Duquesne University delivers a quality research experience, with a focus on computational and theoretical chemistry, that motivates undergraduates and faculty to achieve their highest academic performance and best prepare them for scientific research and discovery. The core idea is to establish meaningful, year-round, and long-term research collaborations driven by the need for academic productivity and excellence in undergraduate training. The REU site serves national interest by promoting advances in the basic sciences, training and support of the U.S. scientific workforce, and advancing prosperity and welfare. This project focuses on strong financial and infrastructure support of research collaborations that invigorate PUI/HBC/LSAMP faculty, who in turn directly impact students and learning environments at their home institutions. Duquesne has NSF-funded resources, established research programs, proven record in student placement, and strong partnerships with local industry. REU students receive explicit training to reinforce the scientific method, scientific writing and speaking, ethics, safety, and workshops on state-of-the-art instrumentation to complement their experimental research and build invaluable skill sets. Each student has the opportunity to present their research locally, regionally, and nationally to expand their professional exposure and networking to make more informed career decisions and best prepare for graduate school. The PUI/HBC/LSAMP faculty are empowered through meaningful and productive academic collaboration to enhance their professional development. The broader impacts of this work include meaningful research experiences to attract and retain the nation’s diverse student talent pool, which has the consequence of enhancing and diversifying the U.S. workforce by adding experts in the fields of chemistry or biochemistry.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

本科生的研究经验（REU）网站奖给位于宾夕法尼亚州匹兹堡的迪克讷大学，支持10名学生在2023-2025年的夏天进行为期10周的培训。由化学部资助，迪克讷REU网站继续影响专业化学职业和本科生和教师的教育，从阿巴拉契亚地区机构有限的研究基础设施和/或从代表性不足的人口。为了迎接这一挑战，迪克讷大学提供高质量的研究体验，重点是计算和理论化学，激励本科生和教师实现最高的学术成绩，并为科学研究和发现做好最好的准备。其核心思想是建立有意义的，全年的，长期的研究合作，由学术生产力和卓越的本科生培训的需要驱动。REU网站通过促进基础科学的进步，培训和支持美国科学工作者，促进繁荣和福利来服务国家利益。该项目的重点是强大的财政和基础设施支持的研究合作，振兴PUI/HBC/LSAMP教师，谁反过来直接影响学生和学习环境在他们的家机构。迪克讷拥有NSF资助的资源，建立的研究计划，在学生安置证明记录，并与当地行业强有力的合作伙伴关系。REU学生接受明确的培训，以加强科学方法，科学写作和演讲，道德，安全和最先进仪器的研讨会，以补充他们的实验研究和建立宝贵的技能。每个学生都有机会在当地，地区和全国范围内展示他们的研究成果，以扩大他们的专业曝光和网络，从而做出更明智的职业决策，并为研究生院做好最好的准备。PUI/HBC/LSAMP教师通过有意义和富有成效的学术合作来增强他们的专业发展。这项工作的更广泛的影响包括有意义的研究经验，以吸引和留住国家的多样化的学生人才库，这有加强和多样化的美国劳动力的结果，通过增加化学或生物化学领域的专家。这个奖项反映了NSF的法定使命，并已被认为是值得支持的评估使用基金会的智力价值和更广泛的影响审查标准。

项目成果

Effect of the SARS-CoV-2 Delta-associated G15U mutation on the s2m element dimerization and its interactions with miR-1307-3p

SARS-CoV-2 Delta 相关 G15U 突变对 s2m 元件二聚化的影响及其与 miR-1307-3p 的相互作用

• DOI: 10.1261/rna.079627.123
• 发表时间: 2023
• 期刊: RNA
• 影响因子: 4.5
• 作者: Cunningham, Caylee L.;Frye, Caleb J.;Makowski, Joseph A.;Kensinger, Adam H.;Shine, Morgan;Milback, Ella J.;Lackey, Patrick E.;Evanseck, Jeffrey D.;Mihailescu, Mihaela-Rita
• 通讯作者: Mihailescu, Mihaela-Rita