REU Site: Engineering for Healthcare

REU 网站：医疗保健工程

• 批准号: 1757128
• 负责人: Douglas Spearot
• 金额: $ 37.89万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-15 至 2022-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1757128&HistoricalAwards=false
• 关键词: REU; Site; Engineering; Healthcare

This REU Site: Engineering for Healthcare at the University of Florida (UF), will involve a diverse cohort of students in convergent research and curricula focused on critical engineering challenges in healthcare. In 2013, the healthcare industry in the United States was 17.7% of gross domestic product; this is expected to grow over the next decade or more. This proposal focuses on the cross-disciplinary impact of engineering research on the healthcare field. The research to be conducted by REU Participants falls into one of three categories: (i) engineered and manufactured surfaces and devices for health applications, (ii) engineering advances for medical treatment, and (iii) modeling of healthcare relevant materials and processes. The University of Florida is an ideal location for a NSF REU Site with this intellectual focus, as strong partnerships currently exist between the UF Herbert Wertheim College of Engineering, the Institute of Food and Agricultural Sciences, UF Health Shands Hospital (along with related medical institutes such as the McKnight Brain Institute), and the Veterinary School - all co-located on the same university campus.REU Participants will gain foundational skills through training workshops on the scientific method, and via hands-on research activities. REU Participants will gain an awareness of how traditional engineering principles can be extended to address modern engineering problems in the healthcare field and in society. REU participants will (i) engage in high-impact research in partnership with engineering faculty and graduate student mentors, (ii) attend workshops dedicated to research practices and communications training, (iii) attend a seminar series where important high-priority challenges in healthcare that require engineering solutions are elucidated through partnerships with clinical faculty or healthcare professionals, and (iv) disseminate their research results through both oral and written communications. Via this REU Site, each cohort of students will gain foundational skills through training workshops on the scientific method, and via hands-on research activities. REU participants will gain an awareness of how traditional engineering principles can be extended to address modern engineering problems in the healthcare field and in society. Finally, REU participants will improve their oral and written communication skills through symposium-style presentations and written project reports. Because of this training, REU Participants will be better prepared to succeed in their current undergraduate curriculum and be better prepared to make a positive impact upon entering industry or graduate school.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

本REU网站：工程医疗保健在佛罗里达（UF）的大学，将涉及学生的融合研究和课程集中在医疗保健的关键工程挑战的多样化队列。2013年，美国医疗保健行业占国内生产总值的17.7%，预计在未来十年或更长时间内将继续增长。该提案侧重于工程研究对医疗保健领域的跨学科影响。REU参与者将进行的研究福尔斯三类：（i）用于健康应用的工程和制造表面和设备，（ii）医疗工程进展，以及（iii）医疗保健相关材料和过程的建模。佛罗里达大学是NSF REU网站的理想位置，具有这种智力重点，因为UF赫伯特韦特海姆工程学院，食品和农业科学研究所，UF健康尚兹医院之间目前存在强大的合作伙伴关系（沿着相关的医学机构，如麦克奈特脑研究所），和兽医学院-都位于同一个大学校园。REU参与者将通过科学方法的培训研讨会和实践研究活动获得基本技能。REU参与者将了解传统工程原理如何扩展到解决医疗保健领域和社会中的现代工程问题。REU参与者将（i）与工程学院和研究生导师合作进行高影响力的研究，（ii）参加致力于研究实践和通信培训的研讨会，（iii）参加一系列研讨会，通过与临床教师或医疗保健专业人员的合作关系，阐明医疗保健中需要工程解决方案的重要高优先级挑战，及（iv）透过口头及书面交流，传播研究成果。 通过这个REU网站，每个学生群体将通过科学方法的培训研讨会和实践研究活动获得基本技能。 REU参与者将了解如何将传统工程原理扩展到解决医疗保健领域和社会中的现代工程问题。 最后，REU参与者将通过研讨会式的演讲和书面项目报告提高他们的口头和书面沟通技巧。 由于此次培训，REU参与者将为在当前的本科课程中取得成功做好更好的准备，并为进入行业或研究生院产生积极影响做好更好的准备。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响力审查标准进行评估，被认为值得支持。

项目成果

Combining 3D Magnetic Force Actuator and Multi-Functional Fluorescence Imaging to Study Nucleus Mechanobiology

结合 3D 磁力致动器和多功能荧光成像研究核力学生物学

• DOI: 10.3791/64098
• 发表时间: 2022
• 期刊: Journal of Visualized Experiments
• 作者: Huang, Miao;Wang, Heyang;Delgado, Alfredo A.;Reid, Tyler A.;Long, Julian;Wang, Shu;Sussman, Hayley;Guan, Juan;Yamaguchi, Hitomi;Tang, Xin
• 通讯作者: Tang, Xin

Towards an integrative understanding of cancer mechanobiology: calcium, YAP, and microRNA under biophysical forces

全面了解癌症力学生物学：生物物理力下的钙、YAP 和 microRNA

• DOI: 10.1039/d1sm01618k
• 发表时间: 2022
• 期刊: Soft Matter
• 影响因子: 3.4
• 作者: Liang, Chenyu;Huang, Miao;Li, Tianqi;Li, Lu;Sussman, Hayley;Dai, Yao;Siemann, Dietmar W.;Xie, Mingyi;Tang, Xin
• 通讯作者: Tang, Xin