MRI: Acquisition of a Laser-Based Biomolecular Imager

福尔曼大学被授予一项奖励，以支持购买生物分子成像仪，供生物和化学系的教职员工和学生共享使用。福尔曼大学生物系和化学系的教职员工致力于保持强大的本科生研究计划，对下一代科学家的长期培训和发展产生积极影响。为了提供这些经验，教员们积极参与新的研究项目，并在实验室指导本科生。新的成像系统每年将对至少35名本科生研究人员产生积极影响，并支持通过NSF-面向本科生的研究经验资助的项目。它将为高中教师和学生提供研究体验。此外，来自该地区历史上的黑人学院和大学、两年制学院和其他地区本科院校的教职员工和本科生将可以使用生物成像仪来满足他们的研究需求。Furman教授拥有广泛的研究项目，包括含有AT-Hook的蛋白质的生物物理表征；阐明桥粒在细胞迁移中的协调作用；调查硫和硒化合物保护DNA免受活性氧损伤的能力；表征新型铬(III)-二亚胺络合物的DNA加合物和光切割性质；研究真菌病原体的胁迫反应；阐明染色质缩合和解缩在T细胞活动中的作用；以及对暴露于环境应激源的海葵进行遗传指纹分析。新的成像仪系统将通过提高数据采集速度、灵敏度、质量和灵活性来帮助所有这些努力。教师研究将导致在各自领域的会议上发表演讲，并在国家传播的、同行评议的期刊上发表论文。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to Furman University to support the acquisition of a biomolecular imager for shared use amongst faculty, staff and students in the Biology and Chemistry departments. Faculty in the Biology and Chemistry departments at Furman University are committed to maintaining strong undergraduate research programs that positively impact the long-term training and development of the next generations of scientists. To provide these experiences, faculty are actively engaged in novel research programs and in the mentorship of undergraduate students in the lab. The new imager system will positively impact at least 35 undergraduate researchers each year and support programs funded through NSF-Research Experiences for Undergraduates. It will enable research experiences for high school teachers and students. In addition, faculty and undergraduates from historically black colleges and universities in the region, two-year colleges, and other regional undergraduate institutions will have access to the bioimager for their research needs. Furman faculty have wide-ranging research projects that include the biophysical characterization of AT-hook containing proteins; the elucidation of the role for desmosomes in the coordination of cell migration; investigating compounds of sulfur and selenium for their ability to protect DNA from reactive oxygen species damage; characterizing the DNA adduct and DNA photocleavage properties of novel Cr (III)-diimine complexes; studying the stress response of a fungal pathogen; elucidating the roles of chromatin condensation and decondensation in T-cell activity; and conducting genetic fingerprinting of sea anemones exposed to environmental stressors. The new imager system will aid all of these efforts by improving data acquisition speed, sensitivity, quality, and flexibility. Faculty research will result in presentations at meetings within their respective fields and publications in nationally-disseminated, peer-reviewed journals.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.