MRI: Acquisition of a laser-scanning confocal microscope for research and active learning
MRI:购买激光扫描共焦显微镜用于研究和主动学习
基本信息
- 批准号:2216269
- 负责人:
- 金额:$ 58.2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-01 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
An award is made to California State University, Chico to acquire a confocal microscope system for research and training of diverse students (39.4% from historically under-represented (HU) groups, 50.7% 1st generation college students, 55.4% women) at this Hispanic Serving Institution (HSI). This award supports access to essential technology for competitive basic science research in rural areas north of Sacramento. The imaging technique increases visual resolution and contrast of a microscopic specimen through the capture of multiple two-dimensional images at different depths, and then reconstruction of the three-dimensional structure. Fluorescent dyes can further target specific structures and/or molecules in a cell, tissue, or organism. This technology will enhance undergraduate training in multiple classes within the North State educational community, and be used by Master’s students for research projects. Usage will increase the depth of cellular/organismal/microbial learning, enhance technical skills, and facilitate multidisciplinary projects. Thus, students will be better trained graduates of the CSU system and competitive for jobs or PhD programs. The award also facilitates an increased capacity for faculty led high-quality publications and competitive funding proposals.Confocal microscopy is important to cellular science, but also has applications in other areas of the life sciences (microbiology, genetics, developmental biology), and in materials science (geosciences, engineering, physics). The award enables Chico State and other regional faculty to pursue novel approaches that investigate the role of cellular biomechanics in spinal integrity, geobiology, and animal-microbe interactions. On-site confocal microscopy will allow multidisciplinary approaches to understand genes and the related cellular mechanisms responsive to mechanical stimulation, and how the breakdown of these mechanisms leads to reduced spinal integrity. Confocal microscopy also provides non-invasive, high-resolution images of intact, living or minimally preserved specimens. Projects that look at either living fish embryos or anemone larvae demonstrate the ability to study adaptive changes during growth or symbiotic relations. The confocal microscope will also be applied in undergraduate and graduate projects that seek to characterize the bioavailability of marine iron regenerated by microbial species. Results from the novel research enabled by this award will be disseminated in peer-reviewed journals and at local, national, and international scientific meetings.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
一个奖项是作出加州州立大学,奇科获得共聚焦显微镜系统的研究和培训的不同学生(39.4%来自历史上代表性不足(HU)的群体,50.7%的第一代大学生,55.4%的妇女)在这个西班牙裔服务机构(HSI)。该奖项支持在萨克拉门托北部的农村地区获得有竞争力的基础科学研究的基本技术。该成像技术通过在不同深度捕获多个二维图像,然后重建三维结构来增加显微标本的视觉分辨率和对比度。荧光染料可以进一步靶向细胞、组织或生物体中的特定结构和/或分子。这项技术将加强北州教育界多个班级的本科生培训,并被硕士生用于研究项目。使用将增加细胞/有机体/微生物学习的深度,提高技术技能,并促进多学科项目。因此,学生将更好地训练CSU系统的毕业生和竞争力的工作或博士课程。该奖项还有助于提高教师领导的高质量出版物和有竞争力的资金提案的能力。共聚焦显微镜对细胞科学很重要,但在生命科学的其他领域(微生物学,遗传学,发育生物学)和材料科学(地球科学,工程学,物理学)也有应用。该奖项使奇科州立大学和其他地区的教师能够追求新的方法,研究细胞生物力学在脊柱完整性,地球生物学和动物-微生物相互作用中的作用。现场共聚焦显微镜将允许多学科的方法来了解基因和相关的细胞机制对机械刺激的反应,以及这些机制的分解如何导致脊柱完整性降低。共聚焦显微镜还可以提供完整的、活的或保存最少的标本的非侵入性、高分辨率图像。研究活鱼胚胎或海葵幼虫的项目展示了研究生长或共生关系过程中适应性变化的能力。共聚焦显微镜也将应用于本科生和研究生项目,这些项目旨在表征微生物物种再生的海洋铁的生物利用度。该奖项所支持的新研究成果将在同行评审期刊以及地方、国家和国际科学会议上传播。该奖项反映了NSF的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Kristen Gorman其他文献
Does the extent of glacial cover across watersheds and discharge periods affect dietary resource use of nearshore fishes in the Northern Gulf of Alaska?
流域和排放期的冰川覆盖范围是否影响阿拉斯加北部湾近岸鱼类的膳食资源利用?
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:2
- 作者:
Lindsey Stadler;Kristen Gorman;Vanessa von Biela;Andrew Seitz;Katrin Iken - 通讯作者:
Katrin Iken
Threshold trait architecture of Hsp90-buffered variation
Hsp90 缓冲变异的阈值性状结构
- DOI:
10.1101/016980 - 发表时间:
2015 - 期刊:
- 影响因子:0
- 作者:
Charles C. Carey;Kristen Gorman;Becky Howsmon;A. Aragaki;C. Kooperberg;S. Rutherford - 通讯作者:
S. Rutherford
Implementing Root Cause Analysis and Action: Integrating Human Factors to Create Strong Interventions and Reduce Risk of Patient Harm
实施根本原因分析和行动:整合人为因素以制定强有力的干预措施并降低患者伤害的风险
- DOI:
- 发表时间:
2022 - 期刊:
- 影响因子:2.2
- 作者:
Lawrence A. Wolf;Kristen Gorman;Joshua Clark;Jonathan Gleason;S. Henrickson Parker - 通讯作者:
S. Henrickson Parker
Kristen Gorman的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Kristen Gorman', 18)}}的其他基金
RII Track-4: Using Otolith Geochemistry to Understand the Ocean Ecology of a Changing Alaskan Salmon System
RII Track-4:利用耳石地球化学了解不断变化的阿拉斯加鲑鱼系统的海洋生态
- 批准号:
1929174 - 财政年份:2019
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
相似海外基金
MRI: Acquisition of a Laser Ablation - Inductively Coupled Plasma - Triple Quadrupole - Mass Spectrometer (LA-ICP-QQQ-MS) System For Research and Education
MRI:获取用于研究和教育的激光烧蚀 - 电感耦合等离子体 - 三重四极杆 - 质谱仪 (LA-ICP-MS/MS) 系统
- 批准号:
2320040 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
MRI: Track 1 Acquisition of a Matrix-Assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometer for Analysis of Macromolecules
MRI:轨道 1 获取用于分析大分子的基质辅助激光解吸/电离飞行时间质谱仪
- 批准号:
2320090 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
Equipment: MRI Track 1: Acquisition of a Laser Ablation Time of Flight Inductively-Coupled Plasma Mass Spectrometer for UCSB Researchers and Educators
设备:MRI 轨道 1:为 UCSB 研究人员和教育工作者购买激光烧蚀飞行时间电感耦合等离子体质谱仪
- 批准号:
2320389 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
MRI: Track 1 Acquisition of a 3D Scanning Laser Vibrometer to Enhance Collaborative Research and Teaching
MRI:第 1 轨道采购 3D 扫描激光测振仪以加强协作研究和教学
- 批准号:
2320553 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
Equipment: MRI: Track 1 Acquisition of a Laser System for High Precision Spectroscopy and Trapping Neutral Holmium
设备: MRI:轨道 1 获取用于高精度光谱和捕获中性钬的激光系统
- 批准号:
2319917 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
MRI: Track 1 Acquisition of a Direct Write Laser to Advance Semiconductor Research and Education at Norfolk State University
MRI:第一轨采购直写激光器以推进诺福克州立大学的半导体研究和教育
- 批准号:
2320385 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
Equipment: MRI: Track 1 Acquisition of a Laser Ablation System for ICP-MS to Expand a Broad Range of Analytical Activities and Research Training in the Earth Sciences
设备: MRI:轨道 1 采购用于 ICP-MS 的激光烧蚀系统,以扩大地球科学领域的广泛分析活动和研究培训
- 批准号:
2320703 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
MRI: Track 1: Acquisition of Agilent 8700 Laser Direct Infrared (LDIR) Chemical Imaging System
MRI:轨道 1:采购 Agilent 8700 激光直接红外 (LDIR) 化学成像系统
- 批准号:
2320748 - 财政年份:2023
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
MRI: Acquisition of a Femtosecond Laser/Streak Camera Fluorescence Spectrometer
MRI:获取飞秒激光/条纹相机荧光光谱仪
- 批准号:
2216375 - 财政年份:2022
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant
MRI: Acquisition of a 100 Terawatt Laser Upgrade for Application to Basic and Applied Plasma Physics
MRI:获得 100 太瓦激光升级,用于基础和应用等离子体物理
- 批准号:
2215871 - 财政年份:2022
- 资助金额:
$ 58.2万 - 项目类别:
Standard Grant