NSF-RISE: Enhancement of Research and Education Infrastructure in Nanobiomaterials, Biophysics, Biochemistry, and Environmental Science and Engineering

NSF-RISE：加强纳米生物材料、生物物理学、生物化学以及环境科学与工程方面的研究和教育基础设施

• 批准号: 1829245
• 负责人: Branislav Vlahovic
• 金额: $ 99.99万
• 依托单位: North Carolina Central University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1829245&HistoricalAwards=false
• 关键词: NSF; RISE; Enhancement; Research; Education

Enhancement of Research and Education Infrastructure in Nano biomaterials, Biophysics, Biochemistry, and Environmental Science and EngineeringThe Historically Black Colleges and Universities - Research Infrastructure for Science and Engineering (HBCU-RISE) program supports the development of research capability at Historically Black Colleges and Universities that offer doctoral degrees in science and engineering disciplines. Supported projects have a unifying research focus in one of the research areas supported by the National Science Foundation, a direct connection to the long-term plans of the host department, institutional strategic plan and mission, and plans for expanding institutional research capacity, as well as increasing the production of doctoral students, especially those underrepresented in science, technology, engineering and mathematics.With National Science Foundation support, North Carolina Central University will conduct a project entitled "Enhancement of Research and Education Infrastructure in Nano biomaterials, Biophysics, Biochemistry, and Environmental Science and Engineering". The project will elevate the current doctoral program at North Carolina Central University to a leading research and education program focused on development of advanced nanomaterials for biological applications. The project will: a) establish additional doctoral concentrations in biophysics, biochemistry, and environmental science; b) introduce new courses in Nano biomaterials, bioinstrumentation, and interactions between nanostructures and biological materials; and c) provide financial and research support to doctoral students and research faculty involved in these new concentrations.The project will expand the scope of the Integrated Biosciences doctoral program at North Carolina Central University through the addition of new research and educational programs focused on the intersection between nanoscale materials and biosciences. Project activities include studies on applications of nanoscale materials in the life sciences and medicine, specifically: 1) development of a new generation of biochemical sensors based on quantum confinement and tunneling between nanostructures; 2) development of plasmonic nanostructured devices to improve selectivity and sensitivity in optical skin cancer screening and treatment; 3) design and development of novel multifunctional quantum dots for biological applications; 4) imaging of exosomes using colocalized Raman-scanning force microscopy and reduced graphene based fluorescence imaging marker materials for biological applications; 5) development of smart hybrid nanostructures for biochemical filters, adsorption and isolation of substances and piezoelectric hybrid materials for pressure, temperature and optical sensing devices; 6) quantum calculations to improve understanding of charge transfer and interactions between nanostructures, nanostructures and biological molecules, and between diverse biological molecules; and 7) interaction of nanomaterials and biomaterials, and the impact of nanomaterial on the environment and human health.The vision of this project is to leverage existing resources to provide new pathways for North Carolina Central University students to participate in high impact research as part of the Integrated Bioscience doctoral degree program. This project will broaden the scope of the program, making it accessible to students from a wider range of disciplines, and transform the program into a more comprehensive multidisciplinary research program that will prepare students for an increasingly competitive domestic and international research environment. This project will have a substantial impact on the research and education infrastructure at North Carolina Central University through support for faculty and student researchers and extensive curriculum development across STEM disciplines.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在纳米生物材料，生物物理学，生物化学和环境科学与工程的研究和教育基础设施的增强历史上的黑人学院和大学-研究基础设施的科学和工程（HBCU-RISE）计划支持在历史上的黑人学院和大学的研究能力的发展，提供科学和工程学科的博士学位。支持的项目在国家科学基金会支持的研究领域之一有统一的研究重点，与主办部门的长期计划，机构战略计划和使命直接联系，以及扩大机构研究能力的计划，以及增加博士生的产量，特别是那些在科学，技术，在国家科学基金会的支持下，北卡罗来纳州中央大学将开展一个题为“加强纳米生物材料、生物物理学、生物化学和环境科学与工程的研究和教育基础设施”的项目。 该项目将把北卡罗来纳州中央大学目前的博士课程提升为领先的研究和教育项目，重点是开发用于生物应用的先进纳米材料。 该项目将：a）在生物物理学、生物化学和环境科学方面建立更多的博士学位; B）在纳米生物材料、生物仪器和纳米结构与生物材料之间的相互作用方面引入新课程;以及c）为参与这些新的集中的博士生和研究人员提供财政和研究支持。该项目将扩大北卡罗来纳州中部综合生物科学博士课程的范围大学通过增加新的研究和教育计划，重点是纳米材料和生物科学之间的交叉。项目活动包括研究纳米材料在生命科学和医学中的应用，具体而言：1）开发基于纳米结构之间的量子限制和隧道效应的新一代生物化学传感器; 2）开发等离子体纳米结构装置，以提高光学皮肤癌筛查和治疗的选择性和灵敏度; 4）使用共定位拉曼扫描力显微镜和基于还原石墨烯的荧光成像标记材料对外来体进行成像，用于生物学应用; 5）开发用于生物化学过滤器、物质吸附和隔离的智能混合纳米结构以及用于压力、温度和光学传感装置的压电混合材料; 6）量子计算，以提高对纳米结构、纳米结构和生物分子之间的电荷转移和相互作用的理解，以及不同生物分子之间的联系7）纳米材料与生物材料的相互作用，以及纳米材料对环境和人类健康的影响。该项目的愿景是利用现有资源，为北卡罗来纳州中央大学的学生提供新的途径，作为综合生物科学博士课程的一部分，参与高影响力的研究。学位课程该项目将扩大该计划的范围，使其可供来自更广泛学科的学生使用，并将该计划转变为一个更全面的多学科研究计划，使学生为竞争日益激烈的国内外研究环境做好准备。该项目将对北卡罗来纳州中央大学的研究和教育基础设施产生重大影响，通过支持教师和学生研究人员以及跨STEM学科的广泛课程开发。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

The fractal nature as new frontier in microstructural characterization and relativization of scale sizes within space

分形性质是微观结构表征和空间尺度尺寸相对化的新前沿

• DOI: 10.1142/s0217984920504217
• 发表时间: 2020
• 期刊: Modern Physics Letters B
• 影响因子: 1.9
• 作者: Mitic, Vojislav V.;Lazovic, Goran;Mirjanic, Dragoljub;Fecht, Hans;Vlahovic, Branislav;Arnold, Walter
• 通讯作者: Arnold, Walter

Processing and properties of dense cordierite ceramics obtained through solid-state reaction and pressure-less sintering

固相反应常压烧结致密堇青石陶瓷的制备及性能

• DOI: 10.1080/17436753.2018.1548150
• 发表时间: 2019
• 期刊: Advances in Applied Ceramics
• 影响因子: 2.2
• 作者: Obradović, Nina;Pavlović, Vera;Kachlik, Martin;Maca, Karel;Olćan, Dragan;Đorđević, Antonije;Tshantshapanyan, Ani;Vlahović, Branislav;Pavlović, Vladimir
• 通讯作者: Pavlović, Vladimir

Clausius–Mossotti relation fractal modification

Clausius-Mossotti 关系分形修正

• DOI: 10.1080/00150193.2018.1528926
• 发表时间: 2018
• 期刊: Ferroelectrics
• 影响因子: 0.8
• 作者: Mitić, Vojislav V.;Paunović, Vesna;Lazović, Goran;Kocić, Ljubiša;Vlahović, Branislav
• 通讯作者: Vlahović, Branislav

Discrete mean square approximation applied to error calculation in biomolecules and brownian motion

离散均方近似应用于生物分子和布朗运动的误差计算

• DOI: 10.1142/s0217979221503136
• 发表时间: 2021
• 期刊: International Journal of Modern Physics B
• 影响因子: 1.7
• 作者: Randjelovic, Branislav;Markovic, Bojana;Mitic, Vojislav V.;Aleksic, Sanja;Milosevic, Dusan;Vlahovic, Branislav;Tsay, Shwu-Chen
• 通讯作者: Tsay, Shwu-Chen

On binding energy of trions in bulk materials

• DOI: 10.1016/j.physleta.2018.01.017
• 发表时间: 2017-11
• 期刊: Physics Letters A
• 影响因子: 2.6
• 作者: I. Filikhin;R. Kezerashvili;B. Vlahovic