I-Corps: Low-cost Enrichment Kit for Fast Lead Detection in Water with Low Detection Limit

I-Corps：低成本富集套件，可快速检测水中的铅，检测限低

• 批准号: 1829360
• 负责人: Debora Rodrigues
• 金额: $ 5万
• 依托单位: University of Houston
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1829360&HistoricalAwards=false
• 关键词: Corps; Low; cost; Enrichment; Kit

The broader impact/commercial potential of this I-Corps project is a lead enrichment kit that can allow fast detection of lead in water with low cost and low detection limit. Lead contamination in drinking water is a threat to human beings. Due to its health concern, the Lead and Copper Rule (LCR) has set an action level of 15 µg/L for lead in tap water. Considering the great threat of lead to health even with low concentrations, it is necessary to have lead measurements in water at a regular basis. The proposed project aims to commercialize an inexpensive kit which would allow fast lead detection in water with low detection limit to meet Lead and Copper Rule (15 ppb). The kit provides two main benefits to customers: a lower cost ($4) than current kit ($11) for lead detection which meets Lead and Copper Rule and convenience for field sample measurements.This I-Corps project aims to evaluate the commercial adoption of our inexpensive lead enrichment kit for lead detection. Interviews will be conducted to help identify the potential customers and the market needs, evaluate the commercialization feasibility of the new technology, and optimize the technology to meet the demand of targeted customers. Inspired by findings from our current NSF-project, special enrichment kit was designed to accumulate Pb from water, allowing quick detection of lead in water with low concentrations using the inexpensive detection kit. Additionally, the proposed work will provide the basis for future development and commercialization of new enrichment kits to detect other aqueous contaminants in water with low detection limits.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该I-Corps项目的更广泛影响/商业潜力是一种铅浓缩试剂盒，可以快速检测水中的铅，成本低，检测限低。饮用水中的铅污染对人类健康构成威胁。由于其健康问题，铅和铜规则（LCR）已将自来水中铅的行动水平设定为15微克/升。考虑到即使是低浓度的铅对健康的巨大威胁，有必要定期对水中的铅进行测量。拟议的项目旨在将一种廉价的试剂盒商业化，该试剂盒将允许快速检测水中的铅，检测限低，以满足铅和铜规则（15 ppb）。该试剂盒为客户提供了两个主要好处：成本（4美元）低于目前的铅检测试剂盒（11美元），符合铅和铜规则，方便现场样品测量。这个I-Corps项目旨在评估我们廉价的铅富集试剂盒的商业应用。将进行访谈以帮助识别潜在客户和市场需求，评估新技术的商业化可行性，并优化技术以满足目标客户的需求。受我们当前NSF项目发现的启发，设计了一种特殊的富集试剂盒，用于从水中积累铅，从而可以使用廉价的检测试剂盒快速检测低浓度水中的铅。此外，拟议的工作将为未来开发和商业化的新的浓缩试剂盒，以检测其他水污染物在水中的低检测限提供基础。这一奖项反映了NSF的法定使命，并已被认为是值得通过评估使用基金会的知识价值和更广泛的影响审查标准的支持。