CBMS Conference: Mathematical Molecular Bioscience and Biophysics

该奖项支持2019年5月13日至17日由阿拉巴马大学塔斯卡卢萨分校主办的2019年NSF-CBMS会议《数学分子生物科学与生物物理学》。会议将由密歇根州立大学的魏国伟教授担任首席讲师。在当代生命科学从宏观到微观或分子，从定性和现象学到定量和预测性转变的趋势的推动下，数学分子生物科学和生物物理学已经成为数学和生物学交界处的一个很有前途的交叉学科研究领域。会议将推动生物学研究在分子水平上解决前沿问题，使数学在应对分子生物科学和生物物理学的根本挑战方面发挥更重要的作用。本次会议由十场主讲、其他专家的补充发言和圆桌讨论组成。会议旨在吸引许多初级数学家，包括本科生和研究生、博士后研究员和年轻教师，进入这个新的跨学科领域。此外，会议将使主办大学受益，因为它加强了研究计划，并提高了其对东南部地区同行机构的可见度。数学分子生物科学和生物物理学(MMBB)是指发展数学理论、模型、方法、方案和算法，以阐明分子机制和解决分子生物科学和生物物理学前沿的悬而未决的问题。该系列讲座将向数学和生物学会提供MMBB文献的全面概述。许多数学领域，包括微分方程、泛函分析、调和分析、李群、李代数、几何、图论、拓扑学、组合学、多尺度建模、反问题、最优化、机器学习、随机分析、不确定性量化、模糊逻辑、统计推理和非参数回归，在MMBB中得到了重要的应用，许多成功的应用将在这次会议上得到说明。将确定MMBB前沿的生物学悬而未决的问题，如与药物设计和发现有关的问题，这些问题将鼓励在生物分子结构、功能、动力学和运输的建模和计算方面的新研究方向。更多信息，请参考会议网页：http://cbms.ua.eduThis奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award supports the 2019 NSF-CBMS conference "Mathematical Molecular Bioscience and Biophysics," hosted by University of Alabama, Tuscaloosa, during May 13-17, 2019. The conference will feature Professor Guowei Wei of Michigan State University as the Principal Lecturer. Mathematical molecular bioscience and biophysics has been emerging as a promising interdisciplinary research area at the interface of mathematics and biology, driven by the trends of contemporary life sciences that transform biosciences from macroscopic to microscopic or molecular, and from qualitative and phenomenological to quantitative and predictive. The conference will promote biological studies for solving cutting edge problems at molecular level, so that mathematics can play a more important role in addressing fundamental challenges in molecular biosciences and biophysics. This conference consists of ten principal lectures, together with supplemental presentations by other experts and round table discussions. The conference aims to attract many junior mathematicians, including undergraduate and graduate students, postdoctoral fellows, and young faculty, to enter this new interdisciplinary field. In addition, the meeting will benefit the hosting university by enhancing its research program and raising its visibility to peer institutes in the southeastern region. Mathematical Molecular Bioscience and Biophysics (MMBB) concerns the development of mathematical theories, models, methods, schemes, and algorithms for elucidating molecular mechanisms and for solving open problems at the forefront of molecular biosciences and biophysics. The lecture series will provide a thorough overview of the MMBB literature to mathematical and biological societies. Numerous areas of mathematics, including differential equations, functional analysis, harmonic analysis, Lie groups, Lie algebras, geometry, graph theory, topology, combinatorics, multiscale modeling, inverse problems, optimization, machine learning, stochastic analysis, uncertainty quantification, fuzzy logic, statistical inference, and nonparametric regression, have found important applications in MMBB and many successful applications will be illustrated in this conference. Biological open problems at the forefront of the MMBB, such as those associated with drug design and discovery, which will stimulate new research directions in modeling and computation of biomolecular structure, function, dynamics and transport, will be identified. For more information, please refer to the conference webpage: http://cbms.ua.eduThis award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.