RAPID: Funding the Drosophila Species Stock Center at Cornell University

果蝇属作为生物学的模式系统已有100多年的历史。在神经生物学、医学、遗传学、基因组组织和进化以及发育机制方面的许多进展都是对这类苍蝇进行基础研究的结果。最近迁至康奈尔大学的果蝇物种储备中心(DsSC)是一个全国性的储存库，收集了约250种果蝇和相关属的1400多个活体种群。自20世纪40年代以来，该中心一直保存着这些培养物，并分发给在各种生物学领域工作的研究人员，以促进旨在研究生命基本原理和机制的研究。Dssc的工作人员在果蝇的饲养、自然历史、系统学、进化和生态学领域提供技术专业知识。对本科生、研究生和博士后学者的培训将通过独立的学徒研究和每年一次的果蝇物种鉴定和培养研讨会来促进。该中心保存着30多种已完成全基因组测序的果蝇物种，这个数字每年都在增加。这方面的收集进一步增加了它作为比较研究资源的价值和用途，用于研究表型变化、基因组进化、物种分化之间的关系，并解决从分子机制到形态进化的基本问题。该中心的资源还可直接用于应用科学和其他应用，例如农业和病虫害防治，作为影响美国和全球经济的果蝇害虫物种比较数据的来源。该项目还将通过开发一个新的、用户友好的网站(http://blogs.cornell.edu/drosophila/).)来增加获取信息资源的机会修订后的网站将包含目前正在培养的所有分类群的物种页面，包括关于现有种群和饲养要求以及系统发育关系的信息。物种页面将用照片和用于物种鉴定的形态结构的线条图进行说明。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The genus Drosophila has served as a model system in biology for over 100 years. Many advances in neurobiology, medicine, genetics, genome organization and evolution, and the mechanisms of development are the result of basic research on this group of flies. The Drosophila Species Stock Center (DSSC), recently relocated to Cornell University, is a national repository for a diverse collection of over 1400 living stocks from approximately 250 species of Drosophila and related genera. The DSSC has maintained these cultures since the 1940s and distributes to researchers working in a variety of biological fields to facilitate research aimed at studying the underlying principles and mechanisms of life. DSSC staff provides technical expertise in the areas of husbandry, natural history, systematics, evolution, and ecology of Drosophila. Training for undergraduate, graduate, and postdoctoral scholars will be facilitated through independent research apprenticeships and via an annual workshop on Drosophila Species Identification and Culture.The DSSC maintains over 30 Drosophila species that have had their whole genomes sequenced, a number that is increasing each year. This aspect of the collection further adds to its value and utility as a resource for comparative research for investigating the relationships between phenotypic change, genome evolution, species divergence, and to address fundamental questions from molecular mechanisms to morphological evolution. Resources of the DSSC are also directly useful in applied sciences and other applications, for example, in agriculture and pest control, as a resource of comparative data for Drosophila pest species that impact the US and global economies. This project will also increase access to information resources through the development of a new, user-friendly web site (http://blogs.cornell.edu/drosophila/). The revised web site will contain species pages for all taxa currently in culture, including information on stocks available and rearing requirements, and phylogenetic relationships. Species pages will be illustrated with photos and line drawings of morphological structures used for species identification.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.