Expanding N-Heterocyclic Carbene Surface Chemistry

扩展 N-杂环卡宾表面化学

• 批准号: 1904867
• 负责人: Jeremiah Johnson
• 金额: $ 45.78万
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1904867&HistoricalAwards=false
• 关键词: Expanding; Heterocyclic; Carbene; Surface; Chemistry

With this award, the Macromolecular, Supramolecular and Nanochemistry Program in the Division of Chemistry is funding Dr. Jeremiah A. Johnson from Massachusetts Institute of Technology to make a variety of metallic nanoparticles. Nanoparticles with controlled sizes and attached molecular and metallic groups (ligands) have enabled technological innovations in fields ranging from green catalysis and energy conversion to electronics and therapeutics. Despite many advances, the number of methods available to modify the surfaces of nanoparticles is quite small, and each existing method has significant limitations. For example, metal-sulfur bonds, which are by far the most studied linkages are often not sufficiently stable for certain demanding applications Their synthesis is not always straightforward, and they may possess unwanted color/odor. This research examines the use of a variety of new groups on metal nanoparticles in order to develop materials that may be useful in electronics, nanotherapeutics and other applications. The research has a broader impact on the education of undergraduate and graduate students, especially women and underrepresented minorities. The research team is further broadening the impact of their work by including and mentoring high school teachers from the greater Boston/Cambridge area.This research is focused on the synthesis of novel N-Heterocyclic Carbene (NHC)-metal complexes, new strategies for installation of such NHC-metal complexes onto metallic surfaces, and hybrid organic/inorganic materials that leverage the strength of NHC-metal bonds to achieve stability and versatility. The activities are divided into three independent research thrusts. In the first thrust, functional NHC-gold complexes and nanoparticles are prepared bearing "clickable" functionalities which enable polymerization of alkene-based NHC ligands on gold nanoparticles. In the second thrust, NHC@Au nanoparticles-based hybrid materials are designed to contain block copolymers bearing polyNHC-Au complexes as blocks. These block copolymers are then investigated as templates for the formation of gold nanoparticles. In the third trust, a family of NHC@metal monomer complexes with a variety of metals (e.g. copper, iron, nickel and palladium, is prepared for copolymerization studies that yield novel NHC@metal alloy nanoparticles. The research associated with this work provides new tools for the formation of robust chemical bonds between metals and functional molecules with the potential to have broad impacts across fields including electronics, supported catalysis, nanotherapeutics and green chemistry.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

化学系的大分子、超分子和纳米化学项目将通过该奖项资助麻省理工学院的Jeremiah a . Johnson博士制造各种金属纳米颗粒。纳米颗粒具有可控的尺寸和附着的分子和金属基团（配体），使得从绿色催化和能量转换到电子和治疗等领域的技术创新成为可能。尽管取得了许多进步，但可用于修饰纳米颗粒表面的方法数量相当少，而且每种现有方法都有明显的局限性。例如，迄今为止研究最多的金属-硫键对于某些要求苛刻的应用来说往往不够稳定。它们的合成并不总是直接的，而且它们可能具有不需要的颜色/气味。这项研究考察了金属纳米颗粒上各种新基团的使用，以开发可能在电子、纳米治疗和其他应用中有用的材料。这项研究对本科生和研究生的教育有着更广泛的影响，尤其是对女性和代表性不足的少数族裔。研究小组正在进一步扩大他们工作的影响，包括来自大波士顿/剑桥地区的高中教师，并为他们提供指导。本研究的重点是新型n -杂环卡宾(NHC)-金属配合物的合成，在金属表面安装这种NHC-金属配合物的新策略，以及利用NHC-金属键强度来实现稳定性和多功能性的有机/无机杂化材料。这些活动分为三个独立的研究重点。在第一个重点中，制备了具有“可点击”功能的功能性NHC-金配合物和纳米颗粒，使烯基NHC配体能够在金纳米颗粒上聚合。在第二个推力中，NHC@Au纳米颗粒基杂化材料被设计为含有嵌段共聚物的嵌段聚合物，其嵌段包含polyNHC-Au配合物。然后研究这些嵌段共聚物作为金纳米颗粒形成的模板。在第三个信托，一个家族NHC@metal单体配合物与各种金属(如铜，铁，镍和钯，制备共聚研究，产生新的NHC@metal合金纳米颗粒。与这项工作相关的研究为金属和功能分子之间形成强大的化学键提供了新的工具，这些化学键有可能在电子、支持催化、纳米治疗和绿色化学等领域产生广泛的影响。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。