ACS Symposium on Antimicrobial and Cell-Penetrating Polymers

ACS 抗菌和细胞穿透聚合物研讨会

• 批准号: 1917065
• 负责人: Edmund Palermo
• 金额: $ 0.7万
• 依托单位: Rensselaer Polytechnic Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2020-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1917065&HistoricalAwards=false
• 关键词: ACS; Symposium; Antimicrobial; Cell; Penetrating

This symposium will provide a platform for the dissemination of the current results in the field and will serve as a broad interdisciplinary forum for discussions on the current challenges and opportunities for polymer chemists, biophysicists, and microbiologists. The key contributions will delineate the complex interplay between chemical structure, biophysical properties, and biological activity of synthetic polymers that are designed to mimic the salient features of host defense peptides. Optimization of polymer structures to enhance antibacterial potency and reduce toxicity to human cells will be a key focus area. Additionally, discussions on the mechanisms of action exerted by these synthetic macromolecules will further facilitate their potential future use in a clinical setting. The event is likely to evoke keen interest to researchers who specialize in polymer science and engineering, biophysics, microbiology and biomaterials.This symposium will facilitate establishing collaborative efforts between experimental and computational researchers, as well as bridging the gap between polymer chemists and people in the biophysical sciences. Showcasing the advances of interdisciplinary investigators while training young scientists of the next generation is also a central theme as it provides focusing for new research avenues and fostering the development of the next generation of investigators. Significant are made to enhance the participation of groups underrepresented in science and engineering. The list of confirmed speakers includes 14 female scientists, 3 minorities, and 11 junior researchers (Postdoctoral Researchers and Assistant Professors). Presentations by graduate students and post-doctoral researchers, including members of underrepresented groups, will be strongly encouraged through active advertisement and support for travel expenses.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

本次研讨会将提供一个平台，传播该领域的最新成果，并将作为一个广泛的跨学科论坛，讨论聚合物化学家，生物化学家和微生物学家当前的挑战和机遇。 关键的贡献将描绘复杂的化学结构，生物物理特性和生物活性的合成聚合物，旨在模仿宿主防御肽的显着特征之间的相互作用。 优化聚合物结构以增强抗菌效力并降低对人类细胞的毒性将是一个关键的重点领域。 此外，对这些合成大分子作用机制的讨论将进一步促进其在临床环境中的潜在未来用途。 高分子科学与工程、生物物理学、微生物学和生物材料等领域的研究人员将对本次会议产生浓厚的兴趣。本次会议将促进实验和计算研究人员之间的合作，并弥合高分子化学家和生物物理科学家之间的差距。 展示跨学科研究人员的进步，同时培训下一代年轻科学家也是一个中心主题，因为它为新的研究途径提供了重点，并促进了下一代研究人员的发展。 大力加强在科学和工程领域代表性不足的群体的参与。 确认的发言者名单包括14名女科学家，3名少数民族和11名初级研究人员（博士后研究人员和助理教授）。 研究生和博士后研究人员，包括代表性不足的群体的成员的演讲，将通过积极的广告和支持旅费大力鼓励。这个奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。