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Interaction Mechanics of a Stiff Hollow Tube Penetrating a Soft Nonlinear Material

刚性空心管穿透软非线性材料的相互作用力学

基本信息

批准号：
1917711
负责人：
Parsaoran Hutapea
金额：
$ 39.55万
依托单位：
Temple University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-01 至 2023-12-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1917711&HistoricalAwards=false
关键词：
Interaction Mechanics Stiff Hollow Tube

项目摘要

Recently there has been a substantial and growing interest in the medical community to develop next-generation surgical needles to reduce tissue damage during percutaneous interventional procedures. Innovative solutions to the challenge may be found in nature. Insects such as honeybees, mosquitos, and wasps have sophisticated stinger structures and stinging mechanisms, which help them to effectively steer their stingers to specific targets. This award supports fundamental research to study these insertion mechanisms and to obtain knowledge on insertion mechanics as a basis for designing bioinspired surgical needles. Innovative needling devices employing nature-inspired insertion mechanisms will enhance the effectiveness of various existing percutaneous procedures and improve the patients' comfort, and therefore benefit a wide range of medical diagnoses and treatments including those related to cancers. In addition, bioinspired needles with improved controllability can also help develop new medical procedures for biopsy, drug delivery, brain surgery, and many other percutaneous procedures. Through the course of the research work, this project also aims to educate the next generation of scientists and engineers by mentorship and development of new educational materials. Moreover, this project will enhance the engagement of underrepresented groups and women in STEM education and training, and disseminate the state-of-the-art knowledge obtained from research activities to a broad range of audience including the general public and high school students in a variety of public forums such as science fairs, open house events, and summer programs. Lack of mechanics-based understanding of bioinspired needle-tissue interactions has been a major obstacle preventing effective design and development of transformative surgery needling technologies. This project will address the challenges in applying bioinspired designs to advanced needling technologies by extending our understanding of mechanical interactions between artificial components (bioinspired needles) and biological systems (soft tissues). Achievement of this goal will be facilitated by understanding the insertion and extraction mechanics of bioinspired needles through experimental studies, studying the effect of manufacturing conditions on the mechanical properties of the needle components, and predicting the insertion behavior using analytical and simulation methods. The outcome of this work will provide novel knowledge on mechanical behavior of bioinspired needle under relevant conditions, and assist development of reliable predictive needle-insertion models for advanced surgeries.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

最近，医学界对开发下一代手术针头以减少经皮介入过程中的组织损伤的兴趣日益浓厚。对这一挑战的创新解决方案可能会在大自然中找到。蜜蜂、蚊子和黄蜂等昆虫有复杂的刺结构和刺机制，这有助于它们有效地将刺引导到特定的目标。该奖项支持基础研究，以研究这些插入机制，并获得插入机制方面的知识，作为设计生物灵感手术针的基础。采用自然插入机制的创新针灸设备将增强现有各种经皮穿刺术的有效性，改善患者的舒适性，从而使包括癌症相关的各种医学诊断和治疗受益。此外，具有改进的可控性的生物灵感针还可以帮助开发新的医疗程序，用于活组织检查、药物输送、脑外科手术和许多其他经皮程序。通过研究工作的过程，该项目还旨在通过指导和开发新的教育材料来培养下一代科学家和工程师。此外，该项目将加强代表不足的群体和妇女参与STEM教育和培训，并通过各种公共论坛，如科学博览会、开放参观活动和暑期计划，向包括普通公众和高中生在内的广泛受众传播从研究活动中获得的最新知识。缺乏对生物启发的针-组织相互作用的基于力学的理解，一直是阻碍变革性外科针刺技术有效设计和开发的主要障碍。这个项目将通过扩大我们对人工部件(生物灵感针)和生物系统(软组织)之间的机械相互作用的理解，来解决将生物灵感设计应用于先进针刺技术的挑战。通过实验研究了解仿生针的插入和拔出机理，研究制造条件对针部件机械性能的影响，并使用解析和模拟方法预测插入行为，将有助于实现这一目标。这项工作的成果将为相关条件下生物灵感针的机械行为提供新的知识，并有助于为高级外科手术开发可靠的预测针头插入模型。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

期刊论文数量（19）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Design and Experimental Evaluation of Mosquito-Inspired Needle Structure in Soft Materials

软材料中仿蚊针结构的设计和实验评估

DOI：
10.1115/imece2020-24320
发表时间：
2020
期刊：
Proceedings of the ASME 2020 International Mechanical Engineering Congress and Exposition
影响因子：
0
作者：
Gidde, Sai Teja;Hutapea, Parsaoran
通讯作者：
Hutapea, Parsaoran

Influence of Composite Polymer Coatings on the Insertion Force of Needle-Like Structure in Soft Materials

复合聚合物涂层对软材料中针状结构插入力的影响

DOI：
10.1115/imece2020-24341
发表时间：
2020
期刊：
Proceedings of the ASME 2020 International Mechanical Engineering Congress and Exposition
影响因子：
0
作者：
Patel, Kavi I.;Zhu, Long;Gidde, Sai Teja;Ren, Fei;Hutapea, Parsaoran
通讯作者：
Hutapea, Parsaoran

An experimental study on the mechanics and control of SMA-actuated bioinspired needle

DOI：
10.1088/1748-3190/acfb65
发表时间：
2023-09
期刊：
Bioinspiration & Biomimetics
影响因子：
3.4
作者：
Sharada Acharya;P. Hutapea
通讯作者：
Sharada Acharya;P. Hutapea

An Analytical Model for Predicting the Deflection of Hollow Surgical Needle in Soft Tissue

预测软组织中空心手术针偏转的分析模型

DOI：
10.1115/imece2021-71532
发表时间：
2021
期刊：
Proceedings of the ASME 2021 International Mechanical Engineering Congress and Exposition
影响因子：
0
作者：
Al-Safadi, Samer;Hutapea, Parsaoran
通讯作者：
Hutapea, Parsaoran

Steering Control Improvement of Active Surgical Needle using Mosquito Proboscis-Inspired Cannula

使用受蚊子长鼻启发的插管改进主动手术针的转向控制