Synthesis of carbohydrate based nanocapsules and their functionalization with glycomimet-ics for cell-specific targeting (A02)

基于碳水化合物的纳米胶囊的合成及其与糖模拟学的功能化，用于细胞特异性靶向（A02）

• 批准号: 239221355
• 金额: --
• 依托单位: Max-Planck-Institut für Polymerforschung
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2013
• 资助国家: 德国
• 起止时间: 2012-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/239221355?language=en
• 关键词: Synthesis; carbohydrate; based; nanocapsules; their

This project combines the use of carbohydrates, both as structural material for the preparation of nanoparticles and nanocapsules and as targeting moieties to achieve selective binding to certain immune cells. By working with polysaccharide based nanocapsules with high loading efficiencies it aims to prepare stimulus responsive carriers, which bind selectively to certain subpopulations of immune cells to release their cargo

该项目结合了碳水化合物的使用，既可以作为制备纳米颗粒和纳米胶囊的结构材料，也可以作为靶向部分，以实现与某些免疫细胞的选择性结合。通过高负载效率的多糖基纳米胶囊的研究，它的目标是制备刺激响应载体，它选择性地结合到某些免疫细胞亚群以释放它们的货物