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NSF-BSF: From microscopic propulsion to macroscale dynamics: Active particle transport in complex environments

NSF-BSF：从微观推进到宏观动力学：复杂环境中的活性粒子传输

基本信息

批准号：
1934199
负责人：
David Saintillan
金额：
$ 30.33万
依托单位：
University of California-San Diego
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-11-01 至 2023-10-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1934199&HistoricalAwards=false
关键词：
NSF BSF microscopic propulsion macroscale

项目摘要

Suspensions of self-propelled microparticles, or "microswimmers," whether biological or synthetic, have generated considerable interest over the last decade in a wide variety of disciplines, from biophysics to materials science to engineering. From a biological standpoint, understanding locomotion strategies of microswimmers is relevant to reproduction, the spread of disease and contamination processes in the environment. In engineering, active microparticles have been designed to transport material on small scales and to actuate gears and other devices. Nevertheless, the widespread use of microswimmers in practical applications is limited by an incomplete understanding of their propulsion strategies, interactions with their environment, and macroscale transport properties. This project, which is a collaboration between University of California - San Diego and the Technion, will use mathematical modeling and numerical simulations to enhance fundamental understanding of active particle transport in complex environments and geometries and the relationships between microscale propulsion and macroscale transport and hydrodynamics. This project will also support educational and outreach activities by engaging graduate and undergraduate students in the research, by incorporating the research in courses at UCSD and the Technion, and by presenting a summer introductory course on fluid mechanics for high-school students.This project will apply a combination of mathematical modeling and high-fidelity numerical simulations to address outstanding problems related to propulsion mechanisms, effective transport, and large-scale dynamics of microswimmers and their suspensions. The project will examine propulsion modalities of autophoretic colloids and will improve on existing models of self-diffusiophoretic propulsion by elucidating the effects of solute convection and relaxation, particle shape and interactions with rigid or soft boundaries. The team will also develop statistical models of microswimmer transport by using macrotransport theory and mean-field modeling to investigate long-time transport properties of self-propelled swimmers in channels as well as periodic porous media in both dilute and semi-dilute systems. Finally, the project will connect its themes by developing statistical descriptions of phoretic swimmers for problems where the phoretic mechanism and statistics of transport are coupled.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

悬浮的自推进微粒，或“微泳者”，无论是生物或合成的，在过去十年中产生了相当大的兴趣，在各种学科，从生物物理学到材料科学工程。从生物学的角度来看，了解微泳者的运动策略与繁殖，疾病的传播和环境中的污染过程有关。在工程中，活性微粒被设计成在小规模上运输材料，并驱动齿轮和其他设备。然而，在实际应用中的广泛使用的微型游泳者是有限的不完全理解他们的推进策略，与他们的环境的相互作用，和宏观尺度的运输性能。该项目是加州-圣地亚哥大学和Technion之间的合作，将使用数学建模和数值模拟来增强对复杂环境和几何形状中的主动粒子传输以及微尺度推进和宏观尺度传输与流体力学之间关系的基本理解。该项目还将支持教育和推广活动，让研究生和本科生参与研究，将研究纳入加州大学圣地亚哥分校和以色列理工学院的课程，并为高中生提供夏季流体力学入门课程。该项目将应用数学建模和高保真数值模拟相结合的方法来解决与推进机制有关的突出问题，有效的运输，和大规模的动力学的微型游泳者和他们的悬浮液。该项目将研究自泳胶体的推进模式，并将通过阐明溶质对流和弛豫、颗粒形状以及与刚性或软边界的相互作用的影响来改进现有的自扩散泳推进模型。该团队还将通过使用宏观运输理论和平均场建模来开发microswimmer运输的统计模型，以研究在稀释和半稀释系统中自推进游泳者在通道以及周期性多孔介质中的长时间运输特性。最后，该项目将通过发展泳泳者的统计描述来连接其主题，以解决泳动机制和运输统计耦合的问题。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。