NSF-BSF: From microscopic propulsion to macroscale dynamics: Active particle transport in complex environments

NSF-BSF：从微观推进到宏观动力学：复杂环境中的活性粒子传输

基本信息

批准号：
1934199
负责人：
David Saintillan
金额：
$ 30.33万
依托单位：
University of California-San Diego
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-11-01 至 2023-10-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1934199&HistoricalAwards=false
关键词：
NSF BSF microscopic propulsion macroscale

项目摘要

Suspensions of self-propelled microparticles, or "microswimmers," whether biological or synthetic, have generated considerable interest over the last decade in a wide variety of disciplines, from biophysics to materials science to engineering. From a biological standpoint, understanding locomotion strategies of microswimmers is relevant to reproduction, the spread of disease and contamination processes in the environment. In engineering, active microparticles have been designed to transport material on small scales and to actuate gears and other devices. Nevertheless, the widespread use of microswimmers in practical applications is limited by an incomplete understanding of their propulsion strategies, interactions with their environment, and macroscale transport properties. This project, which is a collaboration between University of California - San Diego and the Technion, will use mathematical modeling and numerical simulations to enhance fundamental understanding of active particle transport in complex environments and geometries and the relationships between microscale propulsion and macroscale transport and hydrodynamics. This project will also support educational and outreach activities by engaging graduate and undergraduate students in the research, by incorporating the research in courses at UCSD and the Technion, and by presenting a summer introductory course on fluid mechanics for high-school students.This project will apply a combination of mathematical modeling and high-fidelity numerical simulations to address outstanding problems related to propulsion mechanisms, effective transport, and large-scale dynamics of microswimmers and their suspensions. The project will examine propulsion modalities of autophoretic colloids and will improve on existing models of self-diffusiophoretic propulsion by elucidating the effects of solute convection and relaxation, particle shape and interactions with rigid or soft boundaries. The team will also develop statistical models of microswimmer transport by using macrotransport theory and mean-field modeling to investigate long-time transport properties of self-propelled swimmers in channels as well as periodic porous media in both dilute and semi-dilute systems. Finally, the project will connect its themes by developing statistical descriptions of phoretic swimmers for problems where the phoretic mechanism and statistics of transport are coupled.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在过去的十年中，从生物物理学到材料科学再到工程学，在过去的十年中，自propelled微粒或“微武器”的悬浮液（无论是生物学还是合成）引起了极大的兴趣。从生物学的角度来看，了解微武者的运动策略与繁殖，疾病的传播和环境中的污染过程有关。在工程学中，已经设计了活跃的微粒，以便在小尺度上运输材料，并启动齿轮和其他设备。然而，在实际应用中广泛使用Microswimmers受到对其推进策略，与环境的相互作用以及宏观运输属性的不完全理解的限制。该项目是加利福尼亚大学圣地亚哥大学与技术之间的合作，将使用数学建模和数值模拟来增强对复杂环境和几何形状中主动粒子运输的基本理解，以及显微镜推进与宏观运输和流体动力学之间的关系。 This project will also support educational and outreach activities by engaging graduate and undergraduate students in the research, by incorporating the research in courses at UCSD and the Technion, and by presenting a summer introductory course on fluid mechanics for high-school students.This project will apply a combination of mathematical modeling and high-fidelity numerical simulations to address outstanding problems related to propulsion mechanisms, effective transport, and large-scale dynamics of Microswimmers及其悬架。该项目将通过阐明溶质对流和放松，粒子形状以及与刚性或软边界的相互作用的影响来检查自生胶体的推进模态，并将改善现有的自我散发性推进模型。该团队还将通过使用大型转运理论和平均场建模来开发微型快速传输的统计模型，以研究自propelled游泳者在渠道中的长期运输特性，以及在稀释和半稀释系统中的定期多孔培养基。最后，该项目将通过对流动游泳者的统计描述来连接其主题，以解决流动机制和运输统计的问题。该奖项反映了NSF的法定任务，并被认为是通过基金会的知识分子优点和更广泛影响的审查标准通过评估来通过评估来支持的。