I-Corps: Light patternable mesoporous material

I-Corps：可光图案介孔材料

• 批准号: 1934301
• 负责人: Tobias Hanrath
• 金额: $ 5万
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-06-15 至 2020-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1934301&HistoricalAwards=false
• 关键词: Corps; Light; patternable; mesoporous; material

The broader impact/commercial potential of this I-Corps project is to enable significant commercial opportunities in the area of small molecule separation. To capture this opportunity, the potential of this I-Corps project focuses on unprecedented demand of the purification market. Although the emergence of new biomarkers, drug development and point-of-care testing can improve outcomes, the purification step is hindered by requiring lab-scale equipment to separate the impurities and cannot be easily integrated into functional device architectures. Thus, processable mesoporous material potentially has significant need and may have direct impact on wide range of industries including healthcare, biomedical, waste and pollution. These techniques provide a universal route to integrate purification within devices and also provide a platform for multi-detection or diagnosis which is not available yet in the market.This I-Corps project further develops a technology to process mesoporous materials as an enabling platform for a broad range of applications including purification, sensing and bioreactors. Despite the early advances in synthesis of mesoporous materials, technological applications have fallen far behind expectation due, in large part, to the fact that mesoporous materials are formed as powders. This technology addresses this key challenge by fabricating the mesopores in-situ by leveraging unique photo programmable precursor chemistry. The technology enables fabrication of hierarchical mesoporous structures in which the internal micropore structure and macroscopic structure of the materials can be precisely defined.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该I-Corps项目的更广泛影响/商业潜力是在小分子分离领域实现重大商业机会。为了抓住这个机会，I-Corps项目的潜力集中在净化市场前所未有的需求上。虽然新生物标志物的出现、药物开发和即时检测可以改善结果，但纯化步骤因需要实验室规模的设备来分离杂质而受到阻碍，并且不能容易地集成到功能性设备架构中。因此，可加工的介孔材料潜在地具有显著的需求，并且可能对包括医疗保健、生物医学、废物和污染在内的广泛的行业具有直接影响。这些技术提供了一个通用的路线，以整合设备内的净化，也提供了一个平台，多检测或诊断，这是目前还没有在市场上。这个I-Corps项目进一步开发了一种技术，处理介孔材料作为一个使能平台，为广泛的应用，包括净化，传感和生物反应器。尽管在介孔材料的合成方面取得了早期进展，但在很大程度上由于介孔材料以粉末形式形成的事实，技术应用远远落后于预期。该技术通过利用独特的光可编程前体化学原位制造中孔来解决这一关键挑战。该技术能够制造分级介孔结构，其中材料的内部介孔结构和宏观结构可以精确定义。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Processing–Structure–Performance Relationships of Microporous Metal–Organic Polymers for Size-Selective Separations

用于尺寸选择性分离的微孔金属—有机聚合物的加工—结构—性能关系

• DOI: 10.1021/acsami.0c14827
• 发表时间: 2021
• 期刊: ACS Applied Materials & Interfaces
• 影响因子: 9.5
• 作者: Huang, Jen-Yu;Xu, Yuanze;Milner, Phillip J.;Hanrath, Tobias
• 通讯作者: Hanrath, Tobias