I-Corps: Light patternable mesoporous material

I-Corps：可光图案介孔材料

基本信息

批准号：
1934301
负责人：
Tobias Hanrath
金额：
$ 5万
依托单位：
Cornell University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-06-15 至 2020-11-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1934301&HistoricalAwards=false
关键词：
Corps Light patternable mesoporous material

项目摘要

The broader impact/commercial potential of this I-Corps project is to enable significant commercial opportunities in the area of small molecule separation. To capture this opportunity, the potential of this I-Corps project focuses on unprecedented demand of the purification market. Although the emergence of new biomarkers, drug development and point-of-care testing can improve outcomes, the purification step is hindered by requiring lab-scale equipment to separate the impurities and cannot be easily integrated into functional device architectures. Thus, processable mesoporous material potentially has significant need and may have direct impact on wide range of industries including healthcare, biomedical, waste and pollution. These techniques provide a universal route to integrate purification within devices and also provide a platform for multi-detection or diagnosis which is not available yet in the market.This I-Corps project further develops a technology to process mesoporous materials as an enabling platform for a broad range of applications including purification, sensing and bioreactors. Despite the early advances in synthesis of mesoporous materials, technological applications have fallen far behind expectation due, in large part, to the fact that mesoporous materials are formed as powders. This technology addresses this key challenge by fabricating the mesopores in-situ by leveraging unique photo programmable precursor chemistry. The technology enables fabrication of hierarchical mesoporous structures in which the internal micropore structure and macroscopic structure of the materials can be precisely defined.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该I-Corps项目的更广泛的影响/商业潜力是在小分子分离领域赋予大量商业机会。为了抓住这一机会，这个I-Corps项目的潜力集中在净化市场的前所未有的需求上。尽管新生物标志物的出现，药物开发和护理点测试可以改善结果，但通过要求实验室规模的设备将杂质分开，并且不能轻易地集成到功能设备架构中，从而阻碍了纯化步骤。因此，可加工的介孔材料可能有很大的需求，并且可能直接影响包括医疗保健，生物医学，废物和污染在内的广泛行业。这些技术提供了将纯化整合到设备中的通用途径，并为市场中尚不可用的多检测或诊断提供了一个平台。这项I-Corps项目进一步开发了一项技术，可以处理中端材料，以作为纯化，传感和生物反应器在内的广泛应用的促进平台。尽管介孔材料的合成早期进展，但由于介孔材料是粉末形成的事实，技术应用在很大程度上远远落后于期望。该技术通过利用独特的照片可编程前体化学来制造中孔，以应对这一关键挑战。该技术使得可以精确定义材料的内部微孔结构和宏观结构的层次介孔结构进行制造。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛影响的审查标准通过评估来进行评估的。