CSBR: Natural History: Preserving the genomes of the type specimens in the Museum of Comparative Zoology
CSBR:自然历史:在比较动物学博物馆中保存模式标本的基因组
基本信息
- 批准号:1946857
- 负责人:
- 金额:$ 49.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-15 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Species are the basic units of biodiversity. To be recognized, species have to be described and named based on physical specimens, generally known as type specimens or name-bearing specimens. These type specimens must be registered and deposited in a public institution, typically a natural history museum, where they are available to the scientific community for further study. Traditionally, such specimens, whether bones or a dry skin, a pinned insect, or a specimen preserved in fluid, have been stored on museum shelves. However, these conditions are suboptimal for the long-term preservation of their precious DNA. To stop DNA degradation in type specimens, this award provides a means to subsample and cryo-preserve most of the primary types in the Museum of Comparative Zoology (MCZ) to ensure that genomic work can be conducted in the future. In addition, the project provides an opportunity for students to be trained in museum sciences and to work in a state-of-the-art facility for cryopreservation. More than 31,000 data based primary types of non-fossil species are currently housed in the collections of the MCZ. These are preserved in a variety of ways, both dry (e.g., bones, skins, corals, sponges and sea stars) and wet (e.g., ethanol, formalin), but few of these are cryopreserved, and thus their DNA has been degrading rapidly over time. The principal aim of this project is to prevent further DNA degradation in most of the MCZ primary types by subsampling ca. 17,000 specimens and depositing them in the MCZ Cryogenic Collection—a facility where specimens are stored in vapor liquid nitrogen freezers at approximately -167 °C, a gold standard to preserve genetic resources. The MCZ becomes the first natural history museum to conduct a concerted effort to stop degradation of DNA in a large number of its name-bearing specimens. This will ensure the possibility that in the future, every name-bearing specimen may have the possibility to have a sequenced genome associated with it. In addition, the widescale preservation of genetic material these types will have impacts beyond science, providing a resource for future discovery.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
物种是生物多样性的基本单位。为了得到认可,物种必须根据实物标本进行描述和命名,这些实物标本通常被称为模式标本或命名标本。这些模式标本必须登记并存放在公共机构,通常是自然历史博物馆,以便科学界进一步研究。传统上,这些标本,无论是骨头还是干燥的皮肤,被钉住的昆虫,还是保存在液体中的标本,都被保存在博物馆的架子上。然而,这些条件并不适合长期保存它们珍贵的DNA。为了阻止模式标本中的DNA降解,该奖项为比较动物博物馆(MCZ)的大多数主要类型提供了亚样本和冷冻保存的手段,以确保将来可以进行基因组工作。此外,该项目还为学生提供了一个在博物馆科学方面接受培训的机会,并在最先进的低温保存设施中工作。超过31,000种基于数据的非化石物种的主要类型目前被安置在MCZ的收藏中。它们的保存方式多种多样,有干的(如骨头、皮肤、珊瑚、海绵和海星),也有湿的(如乙醇、福尔马林),但很少有冷冻保存的,因此它们的DNA会随着时间的推移而迅速降解。该项目的主要目的是通过对大约17,000个样本进行亚采样,并将它们存放在MCZ低温收集库中,以防止大多数MCZ主要类型的DNA进一步降解。MCZ低温收集库是一种将样本储存在约-167°C的蒸汽液氮冷冻机中的设施,这是保存遗传资源的黄金标准。MCZ成为第一个共同努力阻止大量以其命名的标本DNA降解的自然历史博物馆。这将确保在未来,每一个有名字的标本都有可能有一个与之相关的基因组测序。此外,这些类型的遗传物质的广泛保存将产生超越科学的影响,为未来的发现提供资源。该奖项反映了美国国家科学基金会的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Gonzalo Giribet其他文献
A phylogenomic framework for Vetigastropoda (Mollusca)
Vetigastropoda(软体动物)的系统发育框架
- DOI:
10.1101/736447 - 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
T. J. Cunha;Gonzalo Giribet - 通讯作者:
Gonzalo Giribet
Animal Evolution: Interrelationships of the Living Phyla. Claus Nielsen.
动物进化:活门的相互关系。
- DOI:
- 发表时间:
2013 - 期刊:
- 影响因子:0
- 作者:
Gonzalo Giribet - 通讯作者:
Gonzalo Giribet
The first phylogenetic analysis of Palpigradi (Arachnida) – the most enigmatic arthropod order
最神秘的节肢动物纲 Palpigradi(蛛形纲)的首次系统发育分析
- DOI:
10.1071/is13057 - 发表时间:
2014 - 期刊:
- 影响因子:2.2
- 作者:
Gonzalo Giribet;Erin McIntyre;E. Christian;L. Espinasa;R. Ferreira;O. Francke;M. Harvey;M. Isaia;L. Kováč;Lynn McCutchen;M. F. Souza;M. Zagmajster - 通讯作者:
M. Zagmajster
Pheromone evolution, reproductive genes, and comparative transcriptomics in mediterranean earthworms (annelida, oligochaeta, hormogastridae).
地中海蚯蚓(环节动物、寡毛类、激素胃蠕虫)的信息素进化、生殖基因和比较转录组学。
- DOI:
- 发表时间:
2013 - 期刊:
- 影响因子:10.7
- 作者:
M. Novo;A. Riesgo;A. Fernàndez;Gonzalo Giribet - 通讯作者:
Gonzalo Giribet
Phylogeography, species delimitation and population structure of a Western Australian short-range endemic mite harvestman (Arachnida: Opiliones: Pettalidae: Karripurcellia)
西澳大利亚短程特有螨收获者的系统发育地理学、物种界定和种群结构(蛛形纲:Opiliones:Pettalidae:Karripurcellia)
- DOI:
10.3897/evolsyst.2.25274 - 发表时间:
2018 - 期刊:
- 影响因子:0
- 作者:
Martin Schwentner;Gonzalo Giribet - 通讯作者:
Gonzalo Giribet
Gonzalo Giribet的其他文献
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{{ truncateString('Gonzalo Giribet', 18)}}的其他基金
Collaborative Research: PurSUiT: Understanding the Neotropical Velvet Worms (Onychophora, Peripatidae, Neopatida), a Cretaceous Radiation of Terrestrial Panarthropods
合作研究:追求:了解新热带绒毛虫(甲虫、Peripatidae、Neopatida),一种白垩纪辐射的陆地泛节肢动物
- 批准号:
2154245 - 财政年份:2022
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
Digitization TCN: Collaborative Research: Mobilizing Millions of Marine Mollusks of the Eastern Seaboard
数字化 TCN:合作研究:动员东海岸数百万海洋软体动物
- 批准号:
2001536 - 财政年份:2020
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
Collaborative Research: The Opiliones of New Zealand: Revisionary synthesis and application of species delimitation for testing biogeographic hypotheses
合作研究:新西兰的 Opiliones:用于测试生物地理学假设的物种划界的修订综合和应用
- 批准号:
1754278 - 财政年份:2018
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: Integrative research in gastropods: Phylogeny and shell shape evolution
论文研究:腹足动物综合研究:系统发育和壳形状演化
- 批准号:
1701648 - 财政年份:2017
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
Collaborative Research: Phylogeny and diversification of the orb weaving spiders (Araneae)
合作研究:圆织蜘蛛(Araneae)的系统发育和多样化
- 批准号:
1457539 - 财政年份:2015
- 资助金额:
$ 49.55万 - 项目类别:
Continuing Grant
Collaborative Research: ARTS: Taxonomy and systematics of selected Neotropical clades of arachnids
合作研究:ARTS:选定的新热带蛛形纲分支的分类学和系统学
- 批准号:
1144417 - 财政年份:2012
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: Scalable phylogenomics at the species level: a novel target-gene approach to tracing the global diversification of prorhynchid flatworms (Platyhelminthes)
论文研究:物种水平的可扩展系统发育组学:一种追踪前喙扁形虫(扁形动物)全球多样性的新型靶基因方法
- 批准号:
1210328 - 财政年份:2012
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
Collaborative Research: Resolving old questions in Mollusc phylogenetics with new EST data and developing general phylogenomic tools
合作研究:利用新的 EST 数据解决软体动物系统发育中的老问题并开发通用系统发育工具
- 批准号:
0844881 - 财政年份:2009
- 资助金额:
$ 49.55万 - 项目类别:
Standard Grant
Collaborative Research: AToL: Phylogeny on the Half-shell -- Assembling the Bivalve Tree of Life
合作研究:AToL:半壳的系统发育——组装双壳类生命树
- 批准号:
0732903 - 财政年份:2007
- 资助金额:
$ 49.55万 - 项目类别:
Continuing Grant
AToL: Collaborative Proposal: Assembling the Protostome Tree of Life
AToL:协作提案:组装原口生命树
- 批准号:
0531757 - 财政年份:2006
- 资助金额:
$ 49.55万 - 项目类别:
Continuing Grant
相似国自然基金
Natural超对称中的希格斯物理与暗物质研究
- 批准号:11775039
- 批准年份:2017
- 资助金额:52.0 万元
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Natural超对称在LHC上的现象学研究
- 批准号:11405015
- 批准年份:2014
- 资助金额:22.0 万元
- 项目类别:青年科学基金项目
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