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Classification of injurious loading cycles

有害负载循环的分类

基本信息

批准号：
2003434
负责人：
Amanda Esquivel
金额：
$ 38.3万
依托单位：
Regents of the University of Michigan - Ann Arbor
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2020
资助国家：
美国
起止时间：
2020-06-01 至 2024-05-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2003434&HistoricalAwards=false
关键词：
Classification injurious loading cycles

项目摘要

Rates of anterior cruciate ligament (ACL) injuries continue to rise, especially in female athletes who play multidirectional sports. For example, in high school and collegiate athletes, the incidence of ACL injury is 2 - 6 times higher in females than males. Recent studies have demonstrated that the ACL can rupture due to overuse - specifically due to landing at high forces while pivoting the foot as typically occurs during sports where athletes quickly change direction. This project focuses on using wearable inertial measurement unit (IMU) sensors to identify these types of potentially injurious landings. IMUs, which consist of accelerometers, rate gyroscopes, and magnetic field sensors, can provide information about the acceleration, velocity and position of one body segment with respect to another and have been used to estimate various limb angles and GRFs (Ground Reaction Forces). The first phase or the project is to study soft tissue overuse injury using a wearable device in order to identify injurious loading cycles in a cadaver model. Findings obtained will then be validated in the field with female athletes. This project will produce new knowledge about the relationship between measurements taken by wearable devices and musculoskeletal fatigue loading. The results will lead to better methods for preventing ACL overuse injuries and will provide a framework for the monitoring and prevention of such injuries in athletic, military, firefighter and other populations at risk for injury. Graduate and undergraduate students from two universities (University of Michigan-Dearborn and University of Michigan-Ann Arbor) will work together on this project, increasing their exposure to research and helping to encourage enrollment in biomedical sciences graduate programs.The goal of the project is to study soft tissue overuse injury mechanisms using a wearable inertial measurement unit (IMU) to identify injurious loading cycles and to validate this in the field with a view toward developing injury prevention strategies. Although it is known that fatigue failure of the ACL is possible, there is currently no way to identify loading conditions that cause this failure in the field, what types of activities athletes perform that put them at risk for this manner of loading or what mechanism underlie the apparently random failure of the ACL during athletic moves made hundreds of times before injury. To address these identification needs and achieve the project's goal, the Research Plan is organized under three objectives. The FIRST Objective is to identify injurious loading cycles using a wearable IMU based on kinematic inputs of impact force, knee moments, angles or anterior tibial translation in an in vitro model. Studies are designed to test the hypothesis that IMUs secured to the lower leg and thigh can accurately predict the occurrence of a loading cycle that is known to cause fatigue damage to the ACL. Female cadaver knee specimens will be placed in a tibial torsional device and instrumented with wearable IMUs on the tibia and thigh. Knees will be subjected to repeated loading (100 cycles total) at targeted landing forces, imposed by a drop weight to the end of the distal tibia, with a knee flexion moment and tibial torque designed to simulate a pivot landing. The SECOND Objective is to identify in vivo the athletic activities that correspond to injurious loading conditions, correlate various parameters such as GRF and knee moments to IMU measurements and examine error due to soft tissue motion. Studies are designed to test the hypothesis that there are specific physical activities that occur during multidirectional sports that correspond to known loading conditions that cause overuse ACL injury and linear acceleration and angular acceleration values measured by an IMU can be used to identify these movements in the laboratory. Volunteers from college soccer and basketball teams, instrumented with motion capture markers located on lower extremities and wearable IMUs above and below the knee, will be asked to complete possible injury related tasks, e.g. a jog with a pivot and sidestep and crossover cuts. A 6 degree-of-freedom kinematic model of the lower extremity will be created for each participant using Visual 3D software. The THIRD Objective is to validate the use of an IMU to detect and count potentially dangerous loading cycles in a real-world setting. Studies are designed to test the hypothesis that severe loading cycles can be identified using IMUs in a real-world setting and, unless restricted, these loading cycles can occur at a rate which could cause injury to the ACL because of inadequate time for healing. Adolescent female soccer players who participate in a highly competitive travel soccer program will be fitted with four wearable IMU devices during bi-weekly practices. Undergraduate and graduate students will attend each practice over a one-year period to collect data, video record the event, and provide technical support. The timing of severe loading cycles will be examined using the video recordings to determine whether this changes over time either due to activities in practice or fatigue, as it has been suggested that fatigue may increase the risk of ACL injury. Data will also be compared to determine whether there is a difference between the dominant and non-dominant sides and to examine the effects of age and BMI (Body Mass Index) on the number of severe loading cycles experienced.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

前交叉韧带（ACL）损伤的发生率持续上升，特别是在从事多方向运动的女性运动员中。例如，在高中和大学运动员中，女性ACL损伤的发生率比男性高2 - 6倍。最近的研究表明，ACL可能由于过度使用而断裂-特别是由于在高力量下着陆同时枢转足部，这通常发生在运动员快速改变方向的运动期间。该项目的重点是使用可穿戴惯性测量单元（IMU）传感器来识别这些类型的潜在有害着陆。由加速度计、速率陀螺仪和磁场传感器组成的伊穆斯可以提供关于一个身体部分相对于另一个身体部分的加速度、速度和位置的信息，并且已经用于估计各种肢体角度和GRF（地面反作用力）。该项目的第一阶段是使用可穿戴设备研究软组织过度使用损伤，以识别尸体模型中的有害负载循环。然后，将在女运动员的实地考察中验证所获得的结果。该项目将产生关于可穿戴设备测量值与肌肉骨骼疲劳负荷之间关系的新知识。研究结果将为预防ACL过度使用损伤提供更好的方法，并为监测和预防运动员、军人、消防员和其他有受伤风险的人群中的此类损伤提供框架。两所大学的研究生和本科生（迪尔伯恩大学和安娜堡大学）将在这个项目上合作，该项目的目标是使用可穿戴惯性测量单元（IMU）研究软组织过度使用损伤机制，识别有害载荷循环，并在现场验证，以制定伤害预防策略。虽然已知ACL的疲劳失效是可能的，但是目前没有办法识别在现场引起这种失效的载荷条件，运动员进行的什么类型的活动使他们处于这种载荷方式的风险中，或者在受伤前进行数百次的运动动作期间ACL的明显随机失效的基础是什么机制。为了满足这些识别需求并实现项目目标，研究计划分为三个目标。第一个目标是使用可穿戴IMU基于体外模型中的冲击力、膝关节力矩、角度或胫骨前平移的运动学输入来识别损伤性载荷循环。研究旨在检验以下假设：固定在小腿和大腿上的伊穆斯可以准确预测已知会导致ACL疲劳损伤的载荷循环的发生。将女性尸体膝关节样本置于胫骨扭转装置中，并在胫骨和大腿上安装可穿戴式伊穆斯。膝关节将在目标着陆力下接受重复加载（共100个周期），通过落重施加到胫骨远端末端，膝关节屈曲力矩和胫骨扭矩设计用于模拟枢轴着陆。第二个目标是在体内识别对应于有害负荷条件的运动活动，将各种参数（如GRF和膝关节力矩）与IMU测量值相关联，并检查软组织运动引起的误差。研究旨在检验以下假设：在多方向运动期间发生的特定身体活动对应于导致过度使用ACL损伤的已知负荷条件，IMU测量的线加速度和角加速度值可用于在实验室中识别这些运动。来自大学足球队和篮球队的志愿者将被要求完成可能与伤害相关的任务，例如，具有枢轴和侧步的慢跑和交叉切割，所述志愿者装备有位于下肢上的运动捕捉标记和膝盖上方和下方的可穿戴伊穆斯。将使用Visual 3D软件为每名参与者创建下肢的6自由度运动学模型。第三个目标是验证使用IMU检测和计算现实世界中潜在危险的加载循环。研究旨在检验以下假设：在真实环境中使用伊穆斯可以识别严重载荷循环，除非受到限制，否则这些载荷循环的发生率可能会因愈合时间不足而导致ACL损伤。参加竞争激烈的旅行足球项目的青少年女子足球运动员将在每两周一次的训练中配备四个可穿戴IMU设备。本科生和研究生将参加为期一年的每次实践，收集数据，视频记录事件，并提供技术支持。将使用视频记录检查严重载荷循环的时间，以确定其是否因实践活动或疲劳而随时间发生变化，因为疲劳可能会增加ACL损伤的风险。数据也将进行比较，以确定是否有优势和非优势之间的差异，并检查年龄和BMI（身体质量指数）的严重负荷循环的次数经历的影响。这个奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。