MRI: Acquisition of a Multi-nuclear 400 MHz NMR Spectrometer Equipped with an Autosampler to Support Undergraduate Research at a Hispanic Serving/Minority Serving Institution
MRI: Acquisition of a Multi-nuclear 400 MHz NMR Spectrometer Equipped with an Autosampler to Support Undergraduate Research at a Hispanic Serving/Minority Serving Institution
批准号:
2018196
负责人:
Jeremy Mallari
金额:
$35.12万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-08-15 至 2023-07-31
中文摘要
该奖项由主要研究仪器和化学研究仪器项目支持。加州州立大学圣贝纳迪诺分校(UEC at CSUSB)正在购买一台配备自动换样器的400兆赫核磁共振(NMR)光谱仪,以支持杰里米·马拉里博士及其同事。金伯利·考辛斯,道格拉斯·史密斯和杰森·伯克。该光谱仪允许在各种领域进行研究,例如那些加速具有重要经济意义的化学反应的领域,以及允许对生物学相关物种进行研究。总的来说,核磁共振波谱学是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质,表征分子内原子的特定排列,以及研究溶液或固体状态下分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。该仪器是该机构及附近机构和社区学院化学和生物化学本科学生的教学、研究和研究训练的组成部分。核磁共振光谱仪的奖励旨在加强各级的研究和教育。它尤其影响了铁电和压电系统的发展。该仪器还旨在支持与从海水中提取锂有关的活动。此外,它还有助于开发研究疟疾蛋白酶生物学的化学工具。该光谱仪还将用于研究查尔酮异构酶的演化。该奖项反映了美国国家科学基金会的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。
英文摘要
This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. California State University San Bernardino (UEC at CSUSB) is acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with an automatic sample changer to support Dr. Jeremy Mallari and colleagues Drs. Kimberley Cousins, Douglas Smith and Jason Burke. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting the study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this institution and nearby institutions and community colleges.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts the development of ferroelectric and piezoelectric systems. The instrumentation is also aimed at supporting activities related to the extraction of lithium from seawater. In addition, it benefits the development of chemical tools to investigate malaria protease biology. The spectrometer is also to be used to investigate chalcone isomerase evolution.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
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