MRI: Acquisition of a Multi-nuclear 400 MHz NMR Spectrometer Equipped with an Autosampler to Support Undergraduate Research at a Hispanic Serving/Minority Serving Institution

该奖项由主要研究仪器项目和化学研究仪器项目支持。加州州立大学圣贝纳迪诺分校(UEC At CSUSB)正在购买一台配备自动样品转换器的400 MHz核磁共振(核磁共振)光谱仪，以支持Jeremy Mallari博士及其同事Kimberley Cousins博士、Douglas Smith博士和Jason Burke博士。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及允许研究具有生物相关性的物种。总体而言，核磁共振波谱是化学家用于阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。该仪器是该机构以及附近机构和社区大学本科生化学和生物化学教学和研究培训的组成部分。授予核磁共振光谱仪的目的是加强各级研究和教育。它对铁电和压电系统的发展尤其有影响。该仪器还旨在支持与从海水中提取锂有关的活动。此外，它还有利于开发研究疟疾蛋白水解酶生物学的化学工具。该光谱仪还将用于研究查尔酮异构酶的进化。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. California State University San Bernardino (UEC at CSUSB) is acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with an automatic sample changer to support Dr. Jeremy Mallari and colleagues Drs. Kimberley Cousins, Douglas Smith and Jason Burke. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting the study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this institution and nearby institutions and community colleges.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts the development of ferroelectric and piezoelectric systems. The instrumentation is also aimed at supporting activities related to the extraction of lithium from seawater. In addition, it benefits the development of chemical tools to investigate malaria protease biology. The spectrometer is also to be used to investigate chalcone isomerase evolution.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.