MRI: Acquisition of a Multi-nuclear 400 MHz NMR Spectrometer Equipped with an Autosampler to Support Undergraduate Research at a Hispanic Serving/Minority Serving Institution

MRI：采购配备自动进样器的多核 400 MHz NMR 波谱仪，以支持西班牙裔服务/少数族裔服务机构的本科生研究

• 批准号: 2018196
• 负责人: Jeremy Mallari
• 金额: $ 35.12万
• 依托单位: University Enterprises Corporation at CSUSB
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2018196&HistoricalAwards=false
• 关键词: MRI; Acquisition; Multi; nuclear; 400

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. California State University San Bernardino (UEC at CSUSB) is acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with an automatic sample changer to support Dr. Jeremy Mallari and colleagues Drs. Kimberley Cousins, Douglas Smith and Jason Burke. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting the study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this institution and nearby institutions and community colleges.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts the development of ferroelectric and piezoelectric systems. The instrumentation is also aimed at supporting activities related to the extraction of lithium from seawater. In addition, it benefits the development of chemical tools to investigate malaria protease biology. The spectrometer is also to be used to investigate chalcone isomerase evolution.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学研究仪器计划支持。加州州立大学圣贝纳迪诺（UEC at CSUSB）正在购买一台配备自动进样器的400 MHz核磁共振（NMR）光谱仪，以支持杰里米·马拉里博士及其同事金伯利·伯金斯、道格拉斯史密斯和杰森·伯克博士。该光谱仪可用于各种领域的研究，例如加速具有重要经济意义的化学反应，以及允许研究生物相关物种。一般来说，NMR光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。该仪器是该机构及附近机构和社区学院化学和生物化学本科生教学、研究和研究培训的一个组成部分，授予NMR光谱仪旨在加强各级研究和教育。特别是对铁电和压电系统的发展产生了重要影响。该仪器还旨在支持与从海水中提取锂有关的活动。此外，它有利于开发化学工具来研究疟疾蛋白酶生物学。该光谱仪还将用于调查查耳酮异构酶的演变。该奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。