Stress Neurobiology Workshop, Columbia, SC, May 12-15, 2020

压力神经生物学研讨会的主要目标是将所有专业水平（本科生到正教授）和不同学科的研究人员聚集在一起，分享和讨论与压力反应相关的生理学的最新发现。在之前的会议基础上，研讨会将有一个非常广泛的出席情况，吸引来自许多领域的成员，从而促进与压力研究相关的多学科讨论。研讨会的重点是整合多个系统的压力相关影响，包括生理、免疫、内分泌和自主反应，以及从临床前角度对压力相关疾病的行为结果和恢复力。会议的重点是生物体在整个生命周期中对压力作出反应的基本机制。这个研讨会在南卡罗来纳州哥伦比亚的南卡罗来纳大学举行，是两年一次的研讨会系列的第6次，提供了唯一一个专注于压力神经生物学的小型会议，对学生和pi都开放。本次研讨会为具有共同兴趣的研究人员和学员提供了一个广泛的面对面交流的机会。会议还提供了一些历史视角，向年轻的研究人员介绍了压力神经生物学的标志性研究人员及其开创性的工作。超过一半的演讲者是处于不同职业阶段、来自不同文化或种族背景、拥有不同学历的女性。在这次会议上提出的研究将最终促进对压力如何影响大脑和行为的理解，也将有助于培养这一领域的下一代科学家。近年来，在理解压力的神经生物学方面取得了重大进展，包括介导压力反应和压力适应的神经回路、神经化学和遗传学，这将是我们会议的重点。许多这些进步是由研究大脑和脑-体相互作用的令人兴奋的新方法所支持的，如光遗传学或化学遗传学，通过外泌体和微生物组对脑-体通信的新兴概念理解，以及大数据集分析，成像和生物信息学的改进。本次研讨会的重点是整个生命周期的应激易感性，强调了不同的机制，有助于从青春期到衰老的应激反应，使用不同的应激模型和动物物种。其他课程强调与压力相关的结构、行为、基因组和生理过程的范围，包括下丘脑轴、自主神经功能和突触可塑性。科学计划包括两个主题演讲，五个全体会议，每个会议有五名发言人；两次圆桌会议，其中一次专门讨论无骚扰/歧视的科学环境；两次海报会议（只限见习演讲者）；并为旅行奖获得者（研究生和博士后）提供数据闪电战。这个为期四天的研讨会的一个主要目标是促进所有阶段的受训人员、新调查员、代表性不足的群体和妇女的专业发展。所要求的资金将用于支持学员参加会议的旅费。这些会议上活跃的科学交流也产生新的想法，形成新的合作，支持未来的进步。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The main goal of the Stress Neurobiology Workshop is to bring together researchers from all professional levels (undergraduate student to full professor) and from diverse disciplines to share and discuss recent findings toward understand the physiology associated with stress responses. Based on prior meetings, the Workshop will have a significantly broad attendance profile, attracting members from many fields and thereby facilitating multidisciplinary discussions related to stress research. The Workshop focuses on stress-related effects that integrate multiple systems, including physiology, immune, endocrine, and autonomic responses, as well as behavioral outcomes and resilience to stress-related disorders from a preclinical perspective. The meeting is focused on fundamental mechanisms through which organisms respond to stress in multiple species across the lifespan. This workshop, which takes place at the University of South Carolina in Columbia, SC, is the 6th of a biannual workshop series that offers the only small meeting focused on the neurobiology of stress that is open to students and PIs alike. This Workshop provides an opportunity for extensive face-to-face interactions among researchers and trainees with overlapping interests. The meeting also provides some historical perspective, introducing young investigators to the iconic researchers in stress neurobiology and their seminal work. More than half of the speakers are women at different career stages, from diverse cultural or ethnic backgrounds, and with different academic credentials. The research presented at this meeting will ultimately advance the understating of how stress affects brain and behavior and will also help train the next generation of scientists in this field.In recent years there have been significant advances in understanding the neurobiology of stress, including the neuronal circuits, neurochemistry, and genetics that mediate stress responses and stress adaptation that will be the focus of our meeting. Many of these advances are supported by exciting new approaches to studying the brain and brain-body interactions such as optogenetics or chemogenetics, emerging conceptual understanding of brain-body communication via exosomes and the microbiome, as well as improvements in the analysis of large data sets, imaging and bioinformatics. This workshop focuses on stress susceptibility across the lifespan, highlighting different mechanisms contributing to resilience in stress responses from adolescence to senescence using different stress models and animal species. Additional sessions emphasize the range of structural, behavioral, genomic, and physiological processes associated with stress with sessions on the HPA axis, autonomic function, and synaptic plasticity. The scientific program includes two keynote lectures, five plenary sessions with five speakers each; two roundtable sessions, one of which is dedicated to harassment/discrimination-free scientific environment; two poster sessions (trainee presenters only); and a data blitz presentation for the travel award recipients (Graduate student and Postdoctoral fellows). A major goal of this this four-day workshop is to promote the professional development of trainees of all stages, new investigators, under-represented groups, and women. The requested funds will be used to support travel awards for trainees to attend the meeting. The vigorous scientific exchange at these meetings also generates new ideas and forges novel collaborations that support future advances.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.