RAPID: Computational Modeling of Contact Density and Outbreak Estimation for COVID-19 Using Large-scale Geolocation Data from Mobile Devices

RAPID：使用来自移动设备的大规模地理位置数据进行接触密度计算建模和 COVID-19 爆发估计

• 批准号: 2028687
• 负责人: Constantine Kontokosta
• 金额: $ 20万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-01 至 2021-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2028687&HistoricalAwards=false
• 关键词: RAPID; Computational; Modeling; Contact; Density

The outbreak of COVID-19 has highlighted both the growing global risk of emerging pandemics and the urgent need for enhanced data-driven tools to identify, contain, and mitigate their effects, particularly in dense urban areas. There has been increasing attention given to locational data from smartphones as a way to enhance epidemiological modeling and predict outbreak progression, transmission, and exposure risk. When combined with artificial intelligence or machine learning algorithms, these high resolution data have the potential to vastly improve the granularity and precision of infection and hospitalization estimates. However, the use of locational data raises serious social, ethical, and technical challenges. Trade-offs between the potential public health benefits and the impacts for privacy and civil liberties have started to be debated in earnest within the context of the current pandemic, especially in light of increasing use of these data by private companies to promote targeted advertisements, evaluate retail consumer behavior, and model travel demand, among other applications. Furthermore, the use of these data in the public interest is undermined by an incomplete understanding of the representativeness and bias embedded in these data, particularly in relation to under-represented and vulnerable communities. What is not yet known is the extent of this bias in locational data and how the public health benefits of using these data diminish with spatial and temporal aggregation, which could help to minimize privacy concerns in the collection and use of these data. To address these questions, this project will develop computational models derived from large-scale locational data to (1) estimate the exposure density across a range of temporal (hourly, daily, etc.) and spatial (census block, neighborhood, etc.) scales, which will enable officials and researchers to evaluate and predict transmission rates in a particular area; (2) measure and evaluate the extent and effectiveness of social (physical) distancing efforts over time and comparatively within and across counties and cities, as well as understand the disparate impacts on vulnerable communities and populations; and (3) measure the extent of disease spread based on movement and travel patterns between neighborhoods and communities, which will support predictions of the spatial-temporal patterns of disease outbreak and identify “at-risk” locations based on the aggregated mobility trajectories for areas were infections have been identified or suspected. The project team is particularly concerned with how shelter-in-place orders and exposure risk disproportionately impact low-income and minority communities, and the implications of potential bias in locational data in assessing socioeconomic variations. The project will assess how the usefulness of these models for epidemiologists and public health officials varies with spatial aggregation (e.g. is neighborhood level data superior to county level data) and temporal aggregation (e.g. is a near-real-time model superior to daily or weekly timescales) and provide quantitative performance assessments that can be used for collective decision-making on the trade-offs between health benefits and privacy risk. Project outputs will be made open-source and publicly available as appropriate.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

2019冠状病毒病的爆发凸显了全球新出现的流行病风险日益增加，以及迫切需要增强的数据驱动工具来识别、控制和减轻其影响，特别是在人口密集的城市地区。人们越来越关注智能手机的位置数据，将其作为增强流行病学建模和预测疫情进展、传播和暴露风险的一种方式。当与人工智能或机器学习算法相结合时，这些高分辨率数据有可能大大提高感染和住院估计的粒度和精度。然而，位置数据的使用带来了严重的社会、伦理和技术挑战。在当前疫情的背景下，人们开始认真讨论潜在的公共卫生益处与对隐私和公民自由的影响之间的权衡，特别是考虑到私营公司越来越多地使用这些数据来推广有针对性的广告，评估零售消费者行为，以及模拟旅行需求等应用。此外，由于不完全理解这些数据的代表性和偏见，特别是对代表性不足和弱势群体的代表性和偏见，这些数据的使用也受到损害。目前尚不清楚的是，位置数据中这种偏见的程度，以及使用这些数据的公共卫生效益如何随着空间和时间的汇总而减少，这可能有助于在收集和使用这些数据时尽量减少隐私问题。为了解决这些问题，本项目将开发从大规模位置数据导出的计算模型，以（1）估计一系列时间（每小时，每天等）的暴露密度。和空间（人口普查区块、邻里等）（2）评估和评估社会传播的程度和有效性;（3）评估和评估艾滋病毒/艾滋病的传播率;（4）评估和评估艾滋病毒/艾滋病的传播率;（5）评估和评估艾滋病毒/艾滋病的传播率;（6）评估和评估艾滋病毒/艾滋病的传播率。（物理）随着时间的推移，在县和城市内部和之间进行比较，并了解对弱势社区和人口的不同影响;以及（3）基于邻里和社区之间的移动和旅行模式来测量疾病传播的程度，这将支持对疾病爆发的时空模式的预测，根据已确定或疑似感染的地区的聚集移动轨迹确定的位置。项目小组特别关注就地安置命令和暴露风险如何不成比例地影响低收入和少数族裔社区，以及地点数据在评估社会经济变化方面的潜在偏见的影响。该项目将评估这些模型对流行病学家和公共卫生官员的有用性如何随空间聚集而变化（例如，邻域级数据是否上级于县级数据）和时间聚合（例如，是上级每日或每周时间尺度的近实时模型），并提供可用于贸易集体决策的定量绩效评估-健康利益和隐私风险之间的平衡。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。