SBIR Phase II: Development of a Wireless pH Sensing Stir Bar

SBIR 第二阶段：无线 pH 传感搅拌棒的开发

• 批准号: 2036372
• 负责人: Kristian Scaboo
• 金额: $ 99.97万
• 依托单位: GATE SCIENTIFIC, INC.
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-15 至 2024-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2036372&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Development; Wireless

This Small Business Innovation Research (SBIR) Phase II project will develop networked, wireless chemical and biological sensing for use in wet laboratory and manufacturing environments. The technology to be developed addresses a $16 billion chemical and bioprocessing equipment market with a large growth potential. The ability to cost-effectively monitor these parameters from the research phase to large-scale manufacturing will accelerate the development of critical products such as vaccines and cell therapies, as well as better ensure the quality of everyday consumer goods produced from advanced chemical and biochemical processes.The proposed project includes technical and manufacturing advances that must be made to bring these sensors to market. This effort combines engineering development in networked, wireless communication and miniaturization with analytical chemistry development of key sensing technologies. The innovations include development of manufacturing processes for a novel pH stir bar, development of wireless dissolved oxygen sensing modalities, and methods for achieving wireless sensing in larger-scale, metallic manufacturing vessels. Technology will be developed that enables wireless sensing of key wet process parameters such as pH and dissolved oxygen for chemical and biochemical process monitoring in research and larger-scale manufacturing environments.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个小型企业创新研究(SBIR)第二阶段项目将开发用于潮湿实验室和制造环境的网络化、无线化学和生物传感。即将开发的技术面向160亿美元的化学和生物处理设备市场，具有巨大的增长潜力。从研究阶段到大规模生产，能够经济高效地监测这些参数，将加快疫苗和细胞疗法等关键产品的开发，并更好地确保通过先进的化学和生化工艺生产的日常消费品的质量。拟议的项目包括将这些传感器推向市场必须取得的技术和制造进步。这项工作将网络、无线通信和微型化方面的工程开发与关键传感技术的分析化学开发结合在一起。这些创新包括开发新型pH搅拌棒的制造工艺，开发无线溶解氧传感模式，以及在更大规模的金属制造容器中实现无线传感的方法。将开发能够无线感知关键湿过程参数(如pH和溶解氧)的技术，用于研究和大规模生产环境中的化学和生化过程监控。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。