SBIR Phase I: Measuring and Mapping Pain Intensity onto a 3D Image of the Human Body

SBIR 第一阶段：测量疼痛强度并将其映射到人体 3D 图像上

• 批准号: 2036496
• 负责人: Andru Zeller
• 金额: $ 25.6万
• 依托单位: JUST HEALTH CARE, LTD. CO.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-01 至 2022-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2036496&HistoricalAwards=false
• 关键词: SBIR; Phase; Measuring; Mapping; Pain

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will significantly improve the way clinicians and researchers measure, study and treat pain. Chronic pain affects 20% of U.S. adults and costs $600 billion annually. Opioids are often the first treatment option offered to patients with chronic pain. Currently pain is assessed using simplistic, subjective and generalized visual/verbal scales (1-10) with little ability to localize the origin. It is essential for clinicians and medical researchers to have calibrated and accurate measures of pain to assist patients in determining the underlying disease and directing patients to the most effective therapies. This project will develop a new biomedical tool to quantify pain data for multimodal treatment plans to potentially minimize opioid use. This tool will improve quality of life for people suffering from chronic pain and help those on opioids find better therapies. Furthermore, it will help clinicians with varied levels of training and experience achieve the highest level of exam skill.This Small Business Innovation Research (SBIR) Phase I project will digitize a physical exam by capturing palpation location and pressure and patient pain expression via multiple biosensors to create a personalized “contour” map of pain intensity onto a 3D image of the human body. This comprehensive and calibrated data set can then be used to assist clinicians in developing a more accurate differential diagnosis for the underlying pain condition. This project will advance the hardware and software components for future integration with augmented reality and artificial intelligence modules.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个小企业创新研究（SBIR）第一阶段项目的更广泛的影响/商业潜力将显着改善临床医生和研究人员测量，研究和治疗疼痛的方式。 慢性疼痛影响20%的美国成年人，每年花费6000亿美元。阿片类药物通常是提供给慢性疼痛患者的第一种治疗选择。目前，疼痛是使用简单化、主观和广义的视觉/语言量表（1-10）来评估的，几乎无法定位起源。临床医生和医学研究人员必须校准和准确测量疼痛，以帮助患者确定潜在疾病并指导患者进行最有效的治疗。该项目将开发一种新的生物医学工具，以量化多模式治疗计划的疼痛数据，从而尽可能减少阿片类药物的使用。该工具将改善慢性疼痛患者的生活质量，并帮助阿片类药物患者找到更好的治疗方法。该小型企业创新研究（SBIR）第一期项目将通过多个生物传感器捕捉触诊位置和压力以及患者的疼痛表达，从而在人体的3D图像上创建个性化的疼痛强度“轮廓”图，从而实现身体检查的自动化。然后，这个全面和校准的数据集可以用于帮助临床医生为潜在的疼痛状况制定更准确的鉴别诊断。该项目将推进硬件和软件组件，以便将来与增强现实和人工智能模块集成。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。