NSF/FDA SIR: Safer (polymeric) batteries in medical devices and evolving regulatory framework

NSF/FDA SIR:医疗设备中更安​​全的(聚合物)电池和不断发展的监管框架

基本信息

  • 批准号:
    2037835
  • 负责人:
  • 金额:
    $ 8.34万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-01-01 至 2022-12-31
  • 项目状态:
    已结题

项目摘要

Batteries play an important role in the overall function, reliability, and safety of many medical devices such as pacemakers, implantable cardioverter defibrillators, glucose monitoring devices, and wheelchairs. The insights gained in this one-year NSF/FDA Scholar-In-Residence fundamental research project will aid and inform the development of protocols that demonstrate safety and feasibility of polymer electrolytes for lithium batteries. Success of this project will help streamline the regulation of solid polymer electrolytes in medical devices as a safer alternative. In addition to the impacts on science, the project will also broadly impact engineering education, training students of different educational levels and from diverse backgrounds. Several initiatives are planned, including specific programs that assist in undergraduate and graduate education, graduate student mentoring, and training of high school students. The goal of this project is to better understand the electrochemical, transport, and safety properties of water-containing solid polymer electrolytes. A small amount of water acts as a super plasticizer of the polymer matrix and provides an alternative conduction pathway that significantly improves cation transport. Additionally, the inclusion of water is expected to have a significant impact on the safety of the resulting battery device. Specifically, the Investigator’s propose to study an aqueous solid polymer electrolyte (ASPE) consisting of varying amounts of polyacrylonitrile (PAN), water, and lithium salt as a model system to probe these questions. An investigation of these ASPEs will focus on determining how salt concentration, water concentration, and polymer molecular weight can affect ionic conductivity, cation transport, electrochemical stability, cell safety, and cell performance. Gaining insight into the water-dominant transport mechanism causing the enhanced electrochemical performance of the proposed ASPE systems will greatly benefit the design of the next generation of batteries for medical devices. Full cell devices will undergo safety testing that will help inform an emerging regulatory framework for assessing the safety of polymer electrolytes for use in medical devices.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
电池在起搏器、植入式心律转复除颤器、血糖监测设备和轮椅等许多医疗设备的整体功能、可靠性和安全性方面发挥着重要作用。在这个为期一年的NSF/FDA驻校学者基础研究项目中获得的见解将有助于并为证明锂电池聚合物电解质的安全性和可行性的协议的制定提供信息。该项目的成功将有助于简化固体聚合物电解质在医疗设备中的监管,使其成为一种更安全的替代品。除了对科学的影响外,这项计划也将广泛影响工程教育,培养不同教育水平和不同背景的学生。计划了几项举措,包括协助本科和研究生教育、研究生辅导和高中学生培训的具体项目。该项目的目标是更好地了解含水固体聚合物电解质的电化学、传输和安全特性。少量的水作为聚合物基体的超级增塑剂,提供了一种可替代的传导途径,显著改善阳离子的运输。此外,水的掺入预计会对电池设备的安全性产生重大影响。具体来说,研究者建议研究由不同量的聚丙烯腈(PAN)、水和锂盐组成的水性固体聚合物电解质(ASPE)作为模型系统来探索这些问题。对这些ASPEs的研究将侧重于确定盐浓度、水浓度和聚合物分子量如何影响离子电导率、阳离子传输、电化学稳定性、电池安全性和电池性能。深入了解导致所提出的ASPE系统电化学性能增强的以水为主导的传输机制,将极大地有利于下一代医疗设备电池的设计。全电池装置将进行安全测试,这将有助于为评估用于医疗装置的聚合物电解质的安全性的新监管框架提供信息。该奖项反映了美国国家科学基金会的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Water Domain Enabled Transport in Polymer Electrolytes for Lithium-Ion Batteries
  • DOI:
    10.1021/acs.macromol.0c01960
  • 发表时间:
    2021-03
  • 期刊:
  • 影响因子:
    5.5
  • 作者:
    Matthew D. Widstrom;O. Borodin;K. Ludwig;Jesse E. Matthews;Sahana Bhattacharyya;Mounesha G Garaga
  • 通讯作者:
    Matthew D. Widstrom;O. Borodin;K. Ludwig;Jesse E. Matthews;Sahana Bhattacharyya;Mounesha G Garaga
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Peter Kofinas其他文献

Geometric determinants of sinterless, low-temperature-processed 3D-nanoprinted glass
无烧结低温处理 3D 纳米印刷玻璃的几何决定因素
  • DOI:
    10.1038/s41378-025-00983-7
  • 发表时间:
    2025-07-17
  • 期刊:
  • 影响因子:
    9.900
  • 作者:
    Adira Colton;Ryan N. Halli;M. Rho Ma;Tejaswi Nori;Lucas K. Muller;Kieran J. Barvenik;Mahima Srivastava;Bibek Ramdam;Sunandita Sarker;Eleonora Tubaldi;Peter Kofinas;Kinneret Rand-Yadin;Ryan D. Sochol
  • 通讯作者:
    Ryan D. Sochol
Characterization of network morphology in anion binding hydrogels used for wastewater remediation
  • DOI:
    10.1016/j.polymer.2005.07.084
  • 发表时间:
    2005-11-14
  • 期刊:
  • 影响因子:
  • 作者:
    Dimitri R. Kioussis;Peter Kofinas
  • 通讯作者:
    Peter Kofinas
Molecular imprinting of peptides and proteins in aqueous media
  • DOI:
    10.1007/s00216-007-1327-7
  • 发表时间:
    2007-05-16
  • 期刊:
  • 影响因子:
    3.800
  • 作者:
    Daniel S. Janiak;Peter Kofinas
  • 通讯作者:
    Peter Kofinas

Peter Kofinas的其他文献

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{{ truncateString('Peter Kofinas', 18)}}的其他基金

Safe, High-Performance, Polymer Electrolyte for Lithium Batteries
用于锂电池的安全、高性能聚合物电解质
  • 批准号:
    1157590
  • 财政年份:
    2012
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Continuing Grant
EAGER: Blood Coagulation Inducing Synthetic Polymer Hydrogel
EAGER:凝血诱导合成聚合物水凝胶
  • 批准号:
    1041535
  • 财政年份:
    2010
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Standard Grant
EAGER: Nanostructured Colorimetric Polymer For Pathogen Detection
EAGER:用于病原体检测的纳米结构比色聚合物
  • 批准号:
    0947771
  • 财政年份:
    2009
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Standard Grant
Self-Assembled Polymer Electrolyte Nanoarchitectures for Flexible Batteries
用于柔性电池的自组装聚合物电解质纳米结构
  • 批准号:
    0728975
  • 财政年份:
    2007
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Continuing Grant
SGER: A novel approach to a biocompatible antibody-antigen recognition system using antigen imprinted polymers
SGER:使用抗原印迹聚合物构建生物相容性抗体-抗原识别系统的新方法
  • 批准号:
    0640778
  • 财政年份:
    2006
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Standard Grant
ACT/SGER: Block Copolymer Self-Assembled Nanoarchitectures For Flexible High Energy Density Supercapacitors
ACT/SGER:用于柔性高能量密度超级电容器的嵌段共聚物自组装纳米结构
  • 批准号:
    0442029
  • 财政年份:
    2004
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Standard Grant
Magnetic Oxide Nanoparticles Templated By the Self-Assembly of Block Copolymers
以嵌段共聚物自组装为模板的磁性氧化物纳米颗粒
  • 批准号:
    0347319
  • 财政年份:
    2004
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Continuing Grant
ACT/SGER: Virus Recognition Using Self-Assembled Nanoscale Block Copolymer Patterns
ACT/SGER:使用自组装纳米级嵌段共聚物图案进行病毒识别
  • 批准号:
    0346253
  • 财政年份:
    2003
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Standard Grant
Isomeric Sugar Recognition Using Molecularly Imprinted Polymer Hydrogels
使用分子印迹聚合物水凝胶进行异构糖识别
  • 批准号:
    0303951
  • 财政年份:
    2003
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Standard Grant
2001 Technology for a Sustainable Environment: Toxic and Nutrient Pollution Prevention in the Chesapeake Bay Using Anion Binding Polymeric Hydrogels (TSE01-C)
2001 年可持续环境技术:使用阴离子结合聚合物水凝胶预防切萨皮克湾的有毒和营养物污染(TSE01-C)
  • 批准号:
    0124237
  • 财政年份:
    2001
  • 资助金额:
    $ 8.34万
  • 项目类别:
    Continuing Grant

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