REU Site: Puerto Rico-Chemical Learning Integrated in Materials and Biomolecular applications (PR-CLIMB)

REU 网站：波多黎各化学学习融入材料和生物分子应用 (PR-CLIMB)

• 批准号: 2050493
• 负责人: Arthur Tinoco
• 金额: $ 34.35万
• 依托单位: University of Puerto Rico-Rio Piedras
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-15 至 2024-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2050493&HistoricalAwards=false
• 关键词: REU; Site; Puerto; Rico; Chemical

This Research Experiences for Undergraduates (REU) site award to the University of Puerto Rico-Río Piedras, located in San Juan, PR, supports the training of 10 students for 9 weeks during the summers of 2021-2023. In this program, funded by the Division of Chemistry, undergraduate participants will engage in high caliber interdisciplinary research projects inspired by rebuilding efforts in PR related to the pharmaceutical industry, electrical grid, and water infrastructure. This program also fosters professional development through in-laboratory training, hands-on workshops, and specialized seminars to inspire interest in graduate school in the STEM fields. The broader goal of this site is to train socially conscious scientists who can address community-based problems, to help build the future STEM workforce for Puerto Rico, and to establish a network of STEM professional collaborators. Student participants at this REU site will be matched with research groups conducting fundamental science on the engineering of materials and biomolecules for real-life applications including drug discovery, drug delivery, energy storage, and water purification. The faculty mentors have extensive experience in undergraduate training, and an advanced students or postdoctoral researchers will serve as a co-mentors, providing additional training support to the participants. Alongside research, students will take part in hands-on workshops exposing them to state-of-the-art instrumentation; a seminar series on critical thinking and technical skill development; and orientation on research, graduate school, and career opportunities. A special seminar contextualizes the program’s mission to professionally rehabilitate Puerto Rico, and participants will also go on educational/cultural outings where they will visit a pharmaceutical company and different parts of Puerto Rico. Students majoring in chemistry or related fields are recruited from two-year and four-year institutions in Puerto Rico and the rest of the U.S., particularly from minority serving institutions and from institutions with few research opportunities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

本研究经验的本科生（REU）网站奖波多黎各-里奥皮德拉斯大学，位于圣胡安，PR，支持10名学生的培训9周期间的夏天2021-2023。在该计划中，由化学部资助，本科生参与者将从事高素质的跨学科研究项目，这些项目受到与制药行业，电网和水基础设施相关的公关重建工作的启发。该计划还通过实验室培训，实践研讨会和专业研讨会促进专业发展，以激发研究生院在STEM领域的兴趣。 该网站的更广泛的目标是培养具有社会意识的科学家，他们可以解决基于社区的问题，帮助建立波多黎各未来的STEM劳动力，并建立STEM专业合作者网络。在这个REU网站的学生参与者将与研究小组进行基础科学的材料和生物分子工程的现实生活中的应用，包括药物发现，药物输送，能量存储和水净化相匹配。教师导师在本科培训方面有丰富的经验，高级学生或博士后研究人员将担任共同导师，为参与者提供额外的培训支持。除了研究，学生将参加实践研讨会，让他们接触到最先进的仪器;关于批判性思维和技术技能发展的系列研讨会;以及研究，研究生院和职业机会的方向。一个特别的研讨会将该方案的使命置于专业康复波多黎各的背景下，与会者还将参加教育/文化郊游，参观一家制药公司和波多黎各的不同地区。化学专业或相关领域的学生从波多黎各和美国其他地区的两年制和四年制机构招募，该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Disease-associated non-coding variants alter NKX2-5 DNA-binding affinity.

疾病相关的非编码变异会改变 NKX2-5 DNA 结合亲和力。

• DOI: 10.1016/j.bbagrm.2023.194906
• 发表时间: 2023
• 期刊: Biochimica et biophysica acta. Gene regulatory mechanisms
• 作者: Peña-Martínez,EdwinG;Rivera-Madera,Alejandro;Pomales-Matos,DiegoA;Sanabria-Alberto,Leandro;Rosario-Cañuelas,BrittanyM;Rodríguez-Ríos,JessicaM;Carrasquillo-Dones,EmanuelA;Rodríguez-Martínez,JoséA
• 通讯作者: Rodríguez-Martínez,JoséA