课题基金 / 基金详情

Spiral Waves and Target Patterns

Spiral Waves and Target Patterns
螺旋波和目标模式
批准号:
2106566
负责人:
Bjorn Sandstede
金额:
$35.0万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-07-01 至 2024-06-30

项目摘要

项目成果

Bjorn Sandstede的其他基金

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中文摘要
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英文摘要
Many biological, chemical, and physical processes exhibit spiral waves and target patterns. Spiral waves occur, for instance, in autocatalytic chemical reactions, during cellular signaling of amoebae, and in cardiac tissue where they are often the cause of cardiac arrhythmias and the precursor to ventricular fibrillation and cardiac arrest. Similarly, target patterns appear prominently in autocatalytic reactions and are also often found in systems with small spatial inhomogeneities. This project focuses on understanding when spiral waves and target patterns arise, under which conditions they can be observed, and what mechanisms cause them to change their shape or disappear. The investigator will develop analytical, computational, and geometric tools to answer these questions and apply the findings to models of autocatalytic chemical reactions and wave propagation in cardiac tissue. Graduate and undergraduate students will be engaged in these research activities.This project focuses on understanding existence, multiplicity, stability, and bifurcations of spiral waves and target patterns through the development of spatial-dynamics methodologies that can be applied to a broad range of reaction-diffusion systems. The investigator will establish multiplicity results for one-dimensional spiral waves and target patterns in reaction-diffusion systems using spatial dynamics and apply these results to the Brusselator model. The second project centers on transverse instabilities of spiral waves and target patterns. Transverse instabilities do not contribute to the spectra of planar structures, though they do cause linear instabilities. The aim is to investigate how these instabilities manifest themselves on large bounded disks. The third project focuses on making the numerical computation of spiral spectra more robust by developing preconditioners that rely on appropriate exponential weights to reduce the norm of the resolvent independently of the size of the domain. In the last project, singular perturbation methods will be developed to understand the limits of profiles and spectra of planar spiral waves and target patterns when some of the diffusion coefficients in the model approach zero.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
期刊论文(8)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1089/cmb.2022.0270
发表时间: 2022-10
期刊: Journal of computational biology : a journal of computational molecular cell biology
影响因子: --
作者: [Pinar Demetci;Rebecca Santorella;Manav Chakravarthy;Bjorn Sandstede;Ritambhara Singh]
通讯作者: Pinar Demetci;Rebecca Santorella;Manav Chakravarthy;Bjorn Sandstede;Ritambhara Singh
Unsupervised Integration of Single-Cell Multi-omics Datasets with Disproportionate Cell-Type Representation
具有不成比例的细胞类型表示的单细胞多组学数据集的无监督整合
DOI: 10.1007/978-3-031-04749-7_1
发表时间: 2022
期刊: RECOMB 2022: Research in Computational Molecular Biology
影响因子: --
作者: [Demetçi, Pinar, Santorella, Rebecca, Sandstede, Bjorn, Singh, Ritambhara]
通讯作者: Singh, Ritambhara
DOI: 10.1137/21m1455917
发表时间: 2021-10
期刊: SIAM Journal on Mathematical Analysis
影响因子: 2
作者: [S. Dodson;Bjorn Sandstede]
通讯作者: S. Dodson;Bjorn Sandstede
DOI: 10.1016/j.jde.2022.06.019
发表时间: 2020-10
期刊: Journal of Differential Equations
影响因子: 2.4
作者: [Ross Parker;Bjorn Sandstede]
通讯作者: Ross Parker;Bjorn Sandstede
7
    RTG: Mathematics of Information and Data with Applications to Science
    • 批准号:
      2038039
    • 项目类别:
      Continuing Grant
    • 资助金额:
      $249.16万
    • 财政年份:
      2021
    • 负责人:
      Bjorn Sandstede
    • 依托单位:
    TRIPODS+X: EDU: Collaborative Research: Investigations of Student Difficulties in Data Science Instruction
    • 批准号:
      1839259
    • 项目类别:
      Standard Grant
    • 资助金额:
      $4.54万
    • 财政年份:
      2018
    • 负责人:
      Bjorn Sandstede
    • 依托单位:
    Tripods+X:Res:Collaborative Research: Identification of Gene Regulatory Network Function from Data
    • 批准号:
      1839262
    • 项目类别:
      Standard Grant
    • 资助金额:
      $3.0万
    • 财政年份:
      2018
    • 负责人:
      Bjorn Sandstede
    • 依托单位:
    Dynamics and Stability of Spatially Extended Patterns
    • 批准号:
      1714429
    • 项目类别:
      Standard Grant
    • 资助金额:
      $31.0万
    • 财政年份:
      2017
    • 负责人:
      Bjorn Sandstede
    • 依托单位:
    国内基金
    海外基金
    Baryogenesis, Dark Matter and Nanohertz Gravitational Waves from a Dark Supercooled Phase Transition
    • 批准号:
      24ZR1429700
    • 项目类别:
      省市级项目
    • 资助金额:
      --
    • 批准年份:
      2024
    • 负责人:
      YUICHIRO NAKAI
    • 依托单位: