MRI: Acquisition of a Western Blot Detection Equipment for core facility of a community college

正在向纽约（CUNY）皇后区社区学院（QCC）校园（生物科学地质学系）授予一项合同，以购买LI-COR Odyssey成像系统。该多任务成像系统允许定量蛋白质印迹（WB）、细胞内蛋白质印迹分析、病毒滴定分析和核酸凝胶成像的可视化-仅举几例。QCC是纽约市立大学内的七所社区学院之一，为第一代大学生的多元化人口提供服务，并招收许多原本无法接受高等教育的学生。 84%的QCC学生是非洲裔美国人，亚洲人或拉丁美洲人，超过50%来自收入低于25，000美元的家庭。超过三分之一的生物科学和地质学系的教师每学期指导学生研究技术和道德。我们的教师都非常投资于我们的学生的成功，因为他们走上他们的职业生涯在干领域。该系统的收购将补充校园的本科研究核心设施，其中部分包括实时PCR设备，流式细胞仪和共聚焦显微镜。核心设施中的所有仪器都允许教师向学生介绍尖端的实验方法，并帮助他们为进入STEM劳动力做好准备。新收购的LI-COR Odyssey仪器也将成为QCC生物技术计划和新成立的生物学助理计划教育培训的一个组成部分，从而影响更多的学生。LI-COR Odyssey是QCC及其姊妹校区皇后学院持续研究工作和教学课程的重要组成部分。它的收购将支持各种不同的项目。这些研究包括（a）细胞-细胞相互作用中STAT 3的分子调节，（B）细胞内寄生物对宿主氨基酸转运蛋白的调节，（c）卷柏属中保守的根发育基因的检查，（d）大肠杆菌中固有未折叠多肽底物对DnaK的抑制，（e）用单壁纳米管处理后癌细胞基因表达的研究，（f）刺胞动物行为的分子调控，（g）研究肥胖症和相关合并症中的新蛋白质，（h）CDX 1作为结肠癌对化疗药物敏感性的调节剂的作用和（i）心血管健康相关研究。 使用该工具生成的数据将由教师和学生通过同行评审的期刊出版物以及在区域和国家举行的专业和科学会议上传播。因此，采购该系统将为QCC最近招募的几位早期职业调查人员及其学生开辟新的研究领域。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估来支持。

An award is being made to The City University of New York (CUNY), Queensborough Community College (QCC) campus (Department of Biological Sciences & Geology), to purchase a LI-COR Odyssey Imaging System. This multitasking imaging system allows for the visualization of Quantitative Western blots (WB), In-Cell Western Assays, Viral Titration Assays, and Nucleic Acid Gel Imaging – to name a few of its applications. QCC is one of the seven community colleges within CUNY and serves a diverse population of first-generation college students and admits many students who would otherwise not have access to higher education. 84% of QCC students are African American, Asian, or Latino, and more than 50% come from families with incomes of less than $25,000. More than a third of the Biological Sciences and Geology department’s faculty members mentor students in research techniques and ethics every semester. Our faculty members are exceedingly invested in the success of our students as they embark on their careers in STEM fields. Acquisition of this system will complement the campus’s undergraduate research core facility, which in part includes a real-time PCR equipment, a FACS machine, and a confocal microscope. All instrumentation in the core facility allows faculty to introduce students to cutting-edge experimental methodologies and helps prepare them for entry into the STEM workforce. The newly acquired LI-COR Odyssey instrument will also be an integral part of the educational training in the Biotechnology Program and the newly formed Associates Program in Biology at QCC, thus impacting even more students. The LI-COR Odyssey is an essential part of the continuous research effort and teaching curriculum at QCC and its sister campus, Queens College. Its acquisition will support a variety of diverse projects. These include studies of (a) the molecular regulation of STAT3 in cell-cell interactions, (b) regulation of host amino acid transporters by an intracellular parasite, (c) examination of conserved root development genes in Selaginella (d) inhibition of DnaK by intrinsically unfolded polypeptide substrates in Escherichia coli, (e) investigation of cancer cell gene expression after treatment with single-walled nanotubes, (f) the molecular regulation of Cnidarian behaviors, (g) investigating novel proteins in obesity and associated comorbidities, (h) role of CDX1 as a regulator of colon cancer sensitivity to chemotherapeutic drugs and (i) cardiovascular health-related research. Data generated using the instrument will be disseminated by faculty and students through peer-reviewed journal publications and at both regionally and nationally held professional and scientific conferences. Procuring this system will thus open new frontiers of research for several of QCC’s most recently recruited early career investigators and their students.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.