MRI: Acquisition of a Three Dimensional Raman Imaging System for the Integrated Science Center of SUNY Geneseo

MRI：为纽约州立大学 Geneseo 综合科学中心采购三维拉曼成像系统

• 批准号: 2117780
• 负责人: Kazushige Yokoyama
• 金额: $ 21.01万
• 依托单位: SUNY College at Geneseo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2117780&HistoricalAwards=false
• 关键词: MRI; Acquisition; Three; Dimensional; Raman

This award to SUNY Geneseo is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs to support and improve research by Professor Kazushige Yokoyama and colleagues Jani Lewis, Dori Farthing, Nicholas Warner and Rabeka Alam. This institution is acquiring a three-dimensional Raman imaging system. In general, a Raman microscope begins with a standard optical microscope but then uses a laser to scan the surface of a sample to implement a chemical image over the whole field of view. The laser wavelengths probe the surface and produce a spectrum which identifies chemical components in the material. This gives useful information on the properties of the components. This is a powerful analytical tool for identifying chemical composition qualitatively and semi-quantitatively of various materials. It is being used in several important research areas. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry, biochemistry and geology at this Hispanic Serving Institution (HSI) as well as St John Fisher College. The instrumentation provides direct research experience for students in a variety of courses distributed in various departments and other neighboring universities.The award of this Raman imaging system is aimed at enhancing research and education at all levels. The science enabled by this instrument provides relevant societal benefits by directly characterizing protein folding over a nanoscale metal interface to detect peptide, self-assembly, delivery, or molecular motor for RNA packaging and by identifying morphologically similar but chemically different proteins at a cellular junction. The instrumentation is also used for characterizing the devitrification process in metallurgical slag to understand potential environmental impacts of slag disposal and for characterizing Mars analogue materials.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项授予纽约州立大学Geneseo的奖项得到了主要研究仪器和化学研究仪器计划的支持，以支持和改进Yokoyama教授及其同事Jani刘易斯，Dori Farthing，Nicholas Warner和Rabeka Alam的研究。该机构正在购置一套三维拉曼成像系统。通常，拉曼显微镜以标准光学显微镜开始，但随后使用激光扫描样品的表面以在整个视场上实现化学图像。激光波长探测表面并产生光谱，识别材料中的化学成分。这提供了有关组件属性的有用信息。这是定性和半定量识别各种材料化学成分的强大分析工具。它被用于几个重要的研究领域。该仪器是教学的一个组成部分，以及研究和本科生在化学，生物化学和地质学研究培训在这个西班牙服务机构（HSI）以及圣约翰费舍尔学院。该仪器为学生提供了直接的研究经验，在各种课程分布在各个部门和其他邻近的大学。该拉曼成像系统的奖项旨在加强各级研究和教育。该仪器所支持的科学通过直接表征纳米级金属界面上的蛋白质折叠来检测肽、自组装、递送或RNA包装的分子马达，并通过识别细胞连接处形态相似但化学性质不同的蛋白质，提供了相关的社会效益。该仪器还用于表征冶金炉渣中的脱玻过程，以了解炉渣处置的潜在环境影响，并用于表征火星模拟材料。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。