Collaborative Research: STEPP-NET: Steppe Parasite Networks

合作研究：STEPP-NET：草原寄生虫网络

• 批准号: 2120470
• 负责人: Kurt Galbreath
• 金额: $ 10.54万
• 依托单位: Northern Michigan University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2120470&HistoricalAwards=false
• 关键词: Collaborative; Research; STEPP; NET; Steppe

This project focuses on collecting and describing mammals and their tapeworm and flea parasites from the grasslands of Central Asia. These parasites are highly diverse and ecologically important groups, and many are sensitive indicators of ecosystem quality; further, the parasitic infections they cause can have major negative impacts on wildlife. They also can play an important role in transmitting diseases from wild to domesticated species, and also to humans. However, knowledge of the diversity of parasite species, their geographic distributions, and the precise hosts they occur on and in remains highly fragmentary for much of the world. Central Asian mammals and their associated parasites are particularly highly imperiled but also little studied. This project will collect new material and study how tapeworm and flea parasites from the region evolve in conjunction with their mammalian hosts; it will also consider how the hosts and parasites have responded to various ecological changes across the region. This work is extremely time-sensitive, with many Central Asian ecosystems on the cusp of major land use change as economies shift and major construction occurs in the region. Numerous specimens will be collected, and these will serve as a repository of parasite diversity useful for assessing how future global change influences the distribution of parasites and their hosts. This may ultimately improve public health outcomes. The work will also involve training the next generation of early-career STEM researchers for careers in biodiversity science. The STEPP-NET project will rapidly advance discovery and description of species diversity, host associations, and community assembly, in two mammal-associated macroparasite clades - fleas and cestodes - across the vast grasslands of Central Asia. This region is a prototype for exploring host-parasite dynamics and spillover in response to human activity; historically, as a conduit for ancient Silk Road trade routes, and, currently, from intensifying land use changes and construction. STEPP-NET leverages existing museum specimens, new expeditionary collections in Mongolia and Kazakhstan, and genomic analyses of hosts and parasites to advance knowledge of species boundaries, environmental and host niche breadth, and the exploration of novel host interfaces by focal parasite clades in response to global change pressures. A key outcome of STEPP-NET will be an extended specimen network for Central Asia, in which mammal and parasite specimens are durably linked to derived data and immediately useful in global biodiversity studies and public health initiatives. The project also creates opportunities for STEM graduate and undergraduate students to participate across the spectrum of modern biodiversity science, from international fieldwork to specimen curation and digitization, genomics, and integrative taxonomy. It will build out this community of early-career STEM researchers even further by developing undergraduate and graduate educational modules that are implemented across our institutions and hosted online for broader biodiversity literacy.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个项目的重点是收集和描述来自中亚草原的哺乳动物及其绦虫和跳蚤寄生虫。这些寄生虫是高度多样化和具有生态重要性的群体，许多是生态系统质量的敏感指标；此外，它们引起的寄生虫感染可能对野生动物产生重大负面影响。它们还可以在将疾病从野生物种传播给家养物种以及传播给人类方面发挥重要作用。然而，关于寄生虫物种的多样性、它们的地理分布以及它们在其上和体内发生的准确宿主的知识，对世界上大部分地区来说仍然是高度零散的。中亚哺乳动物及其相关寄生虫尤其危险，但对它们的研究也很少。该项目将收集新的材料，研究该地区的绦虫和跳蚤寄生虫如何与它们的哺乳动物宿主一起进化；它还将考虑宿主和寄生虫如何应对整个地区的各种生态变化。这项工作对时间极为敏感，随着经济转型和该地区的重大建设，许多中亚生态系统正处于重大土地利用变化的边缘。将收集大量标本，这些标本将作为寄生虫多样性的储存库，有助于评估未来全球变化如何影响寄生虫及其宿主的分布。这可能最终会改善公共卫生结果。这项工作还将包括培训下一代职业生涯早期的STEM研究人员，为生物多样性科学领域的工作做准备。STEP-Net项目将迅速推进中亚广大草原上两个与哺乳动物相关的大型寄生虫分支--跳蚤和绦虫--的物种多样性、宿主协会和群落聚集的发现和描述。该地区是探索宿主-寄生虫动态和溢出响应人类活动的原型；历史上，它是古代丝绸之路贸易路线的通道，目前，它是通过加强土地利用变化和建设而产生的。STEPP-Net利用现有的博物馆标本、蒙古和哈萨克斯坦的新探险收藏品以及宿主和寄生虫的基因组分析，促进物种边界、环境和宿主生态位宽度的知识，并探索局部寄生虫分支对新宿主界面的探索，以应对全球变化压力。STEPP-Net的一项关键成果将是扩大中亚的标本网络，在该网络中，哺乳动物和寄生虫标本可持久地与衍生数据相联系，并立即用于全球生物多样性研究和公共卫生倡议。该项目还为STEM研究生和本科生创造机会，参与现代生物多样性科学的各个领域，从国际田野工作到标本保管和数字化、基因组学和综合分类学。它将通过开发本科和研究生教育模块，进一步建立这个职业生涯早期的STEM研究人员社区，这些模块在我们的机构中实施并在线托管，以获得更广泛的生物多样性知识。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Citellinema (Nematoda: Heligmosomidae) from North America with descriptions of 2 new species from the red squirrel Tamiasciurus hudsonicus and 1 from the Canadian woodchuck, Marmota monax

来自北美的 Citellinema（线虫纲：Heligmosomidae），描述了 2 个来自红松鼠 Tamiasciurus hudsonicus 的新物种和 1 个来自加拿大土拨鼠 Marmota monax 的新物种

• DOI: 10.1017/s0031182022000737
• 发表时间: 2022
• 期刊: Parasitology
• 影响因子: 2.4
• 作者: Alnaqeb, Haitham;Galbreath, Kurt E.;Koehler, Anson V.;Campbell, Mariel L.;Jiménez, F. Agustín
• 通讯作者: Jiménez, F. Agustín