RCN-UBE Incubator: Stem Research on Non-model Genomes Network

RCN-UBE孵化器：非模型基因组网络的干研究

• 批准号: 2120626
• 负责人: Nicholas Miller
• 金额: $ 6.77万
• 依托单位: Illinois Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-12-01 至 2024-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2120626&HistoricalAwards=false
• 关键词: RCN; UBE; Incubator; Stem; Research

This project aims to serve the national interest by increasing students' opportunities to participate in scientific research. Participating in research to answer a real-world problem is known to increase a student's persistence in STEM. The science of genomics offers rich opportunities for undergraduate research. Technological advances are helping to unlock the genomic sequences of a growing number of organisms, including many that are critically important to the economy, human health, and the natural environment. Genome sequence data is accumulating so fast that the main bottleneck to understanding it is a large scientifically educated workforce to analyze the data. This project will create a network of genome scientists and educators to create opportunities for undergraduate students to engage in scientific research. The emphasis of this network will focus on the genome of the western corn rootworm. The project will provide a matchmaking service to help genome scientists and educators with complementary interests find each other and set up partnerships. The project will provide resources and guidance to help ensure that the course-based undergraduate research experiences produce both a good education experience for the students and reliable data for the scientists. This incubator project will set up a network that brings together genome scientists in need of help analyzing their data and instructors seeking research opportunities for their undergraduate students. The project team will implement a series of Course-based Undergraduate Research Experiences (CUREs) as modules within existing classes or as standalone classes. CUREs will be implemented at multiple institutions with diverse populations. Student survey data and student work will be analyzed by the leadership team to inform others in the network of evidence-based best practices and to provide guidance for those creating new CUREs. Student work that meets approved standards will be communicated back to the scientific community. For example, manually curated gene models will be submitted to NCBI to improve existing genome annotations. The modest infrastructure requirements needed to implement genomics- based CUREs makes them ideal for extending research opportunities to students at institutions with limited capacity to offer lab-based research experiences. Efforts to grow the network during the incubator phase will place a strong emphasis on recruiting members at 2-year institutions, primarily undergraduate institutions and minority serving institutions to maximize the societal benefits of the network. This project is being jointly funded by the Directorate for Biological Sciences (BIO), Division of Biological Infrastructure, and the Directorate for Education and Human Resources (EHR), Division of Undergraduate Education as part of their efforts to address the challenges posed in Vision and Change in Undergraduate Biology Education: A Call to Action (http://visionandchange.org/finalreport/).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该项目旨在通过增加学生参加科学研究的机会来为国家利益提供服务。众所周知，参与研究以回答现实世界中的问题会增加学生在STEM中的持久性。基因组学科学为本科研究提供了丰富的机会。技术进步正在帮助释放越来越多的生物的基因组序列，包括许多对经济，人类健康和自然环境至关重要的生物。基因组序列数据的积累得如此之快，以至于理解它是一名受过科学教育的劳动力，可以分析数据。该项目将建立一个基因组科学家和教育工作者网络，以创造本科生从事科学研究的机会。该网络的重点将集中在西部玉米根虫的基因组上。该项目将提供一项对接服务，以帮助具有互补兴趣的基因组科学家和教育者相互发现并建立伙伴关系。该项目将提供资源和指导，以帮助确保基于课程的本科研究经验为学生提供良好的教育经验，也可以为科学家提供可靠的数据。 这个孵化器项目将建立一个网络，将基因组科学家汇集在一起​​，需要帮助分析其数据，并为其本科生寻求研究机会。项目团队将作为现有类或独立课程中的模块实施一系列基于课程的本科研究经验（治疗）。疗法将在多个人口的多个机构中实施。领导团队将分析学生调查数据和学生工作，以告知基于证据的最佳实践网络中的其他人，并为创建新疗法的人提供指导。符合批准标准的学生工作将回到科学界。例如，手动策划的基因模型将提交给NCBI，以改善现有的基因组注释。实施基于基因组学的治疗方法所需的适度基础架构要求使其非常适合向有限提供基于实验室的研究经验的机构的学生扩展研究机会。在孵化器阶段发展网络的努力将非常重视在两年制机构的招募成员，主要是本科机构和少数派服务机构，以最大程度地提高网络的社会利益。 This project is being jointly funded by the Directorate for Biological Sciences (BIO), Division of Biological Infrastructure, and the Directorate for Education and Human Resources (EHR), Division of Undergraduate Education as part of their efforts to address the challenges posed in Vision and Change in Undergraduate Biology Education: A Call to Action (http://visionandchange.org/finalreport/).This award reflects NSF's法定任务，并被认为是值得通过基金会的智力优点和更广泛影响的审查标准来评估的值得支持的。