REU Site: Control of Gene Expression for Biological Effect

该REU网站奖授予位于马萨诸塞州波士顿的波士顿大学，将在2022-2024年的夏季为10名学生提供为期10周的培训。预计总共将有30名学生接受该项目的培训，这些学生主要来自研究机会有限的学校或代表性不足的群体。学生将学习如何进行研究，许多人将在科学会议上展示他们的工作成果。该研究将在细胞和分子生物学领域进行，对于培养这一重要研究领域的下一代科学家对于国家的技术发展具有重要意义。该计划的评估将通过在线调查进行。项目结束后，将对学员进行跟踪，以确定他们的职业道路和项目培训成果。该REU站点的学生将主要由波士顿大学生物系的导师进行培训，并将开展与生物影响基因表达控制相关的研究。研究将使用多种生物体和细胞模型进行，并将使用最先进的方法来检查基因表达。除了研究，学生还将接受负责任的研究行为（科学伦理）、工作场所多样性和职业发展方面的培训。学生将通过在线申请表申请该项目，学生将由项目工作人员与潜在的研究导师协商后选择。样本研究项目包括气候变化对珊瑚和海葵模型中基因表达模式的影响，基础和刺激免疫细胞的基因网络，以及涉及肌肉细胞、海胆胚胎和植物结构发育的基因程序。有关该计划的更多信息可访问http://bu.edu/surf，或联系PI （Dr. Thomas D. Gilmore: gilmore@bu.edu）。该奖项反映了NSF的法定使命，并通过基金会的智力价值和更广泛的影响审查标准进行了评估，认为值得支持。

This REU Site award to Boston University, located in Boston, MA, will support the training of 10 students for 10 weeks during the summers of 2022-2024. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities or from under-represented groups, will be trained in the program. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. The research will be conducted in the area of cell and molecular biology and will be important for training the next generation of scientists in this important research area for the nation’s technological development. Assessment of the program will be done through online surveys. Students will be tracked after the program in order to determine their career paths and program training outcomes.Students in this REU Site will be trained primarily by mentors in the Biology Department at Boston University and will carry out research related to the control of gene expression for biological impact. Research will be conducted using a variety of organismal and cell-based models and will use state-of-the-art methods for examining gene expression. In addition to research, students will be trained in responsible conduct of research (scientific ethics), diversity in the workplace, and career development. Students will apply to the program through an online application form, and students will be selected by program staff in consultation with potential research mentors. Sample research projects include the effects of climate change on gene expression patterns in coral and sea anemone models, gene networks in basal and stimulated immune cells, and gene programs involved in the development of muscle cells, sea urchin embryos, and plant structures. More information about the program is available by visiting http://bu.edu/surf, or by contacting the PI (Dr. Thomas D. Gilmore at gilmore@bu.edu).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.