REU Site: Genetic and Biochemical Analysis of Proteins

该REU网站奖授予位于印第安纳州西拉斐特的普渡大学，将在2022年至2024年的夏季为八名学生提供为期十周的培训。预计共有24名学生将接受该项目的培训，这些学生主要来自研究机会有限的学校或代表性不足的群体。参与者将从对研究感兴趣的生命科学和化学专业中招募。学生将发展生命科学研究职业所需的知识和解决问题的能力。该计划将有助于提高国家科技劳动力的准备和多样性。学生将学习如何进行研究，许多人将在科学会议上展示他们的工作成果。基于网络的SALG URSSA评估工具将用于确定培训计划的有效性。课程结束后，将对学生进行跟踪，以确定他们的职业道路。该计划的主要智力目标是提供蛋白质功能实验分析方面的高级培训。为期三天的课程将介绍蛋白质生物化学和实验设计的关键概念。该计划的其余部分将强调全职研究，辅以每周关于研究中的道德行为、专业交流和研究生院申请的课程。在生物化学系，教师指导的项目包括酶机制分析、翻译后蛋白质修饰、表观遗传调控和蛋白质-核酸相互作用，在广泛的生物学背景下研究，包括植物次生代谢、光合作用、组织分化和果蝇视觉系统。许多项目将突出遗传方法在研究蛋白质功能方面的价值。在项目结束时，参与者将在全校范围内的海报会议上展示他们的成果。完整的申请将包括学业成绩单、两封推荐信和一份个人陈述。有关该计划的更多信息，请访问https://ag.purdue.edu/biochem/Pages/REU.aspx，或与PI联系（James Forney博士在forney@purdue.edu）。该奖项反映了美国国家科学基金会的法定使命，并通过基金会的智力价值和更广泛的影响审查标准进行评估，认为值得支持。

This REU Site award to Purdue University, located in West Lafayette, Indiana, will support the training of eight students for ten weeks during the summers of 2022-2024. It is anticipated that a total of 24 students, primarily from schools with limited research opportunities or from an underrepresented group, will be trained in the program. Participants will be recruited from life science and chemistry majors who have an interest in research. Students will develop the knowledge and problem-solving skills required for careers in life sciences research. The program will contribute to increasing the preparation and diversity of the nation’s science and technology workforce. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. The web-based SALG URSSA assessment tool will be used to determine the effectiveness of the training program. Students will be tracked after the program in order to determine their career paths.The primary intellectual goal of the program is to provide advanced training in the experimental analysis of protein function. A three-day orientation will introduce key concepts in protein biochemistry and experimental design. The remainder of the program will emphasize full-time research supplemented with weekly sessions on ethical conduct in research, professional communication, and applications to graduate school. Faculty mentored projects in the Department of Biochemistry include analysis of enzyme mechanisms, post-translational protein modifications, epigenetic regulation, and protein-nucleic acid interactions studied in a wide range of biological contexts including plant secondary metabolism, photosynthesis, tissue differentiation and the drosophila visual system. Many of the projects will highlight the value of genetic approaches to study protein function. Participants will present their results at a university-wide poster session at the end of the program. Complete applications will include academic transcripts, two letters of recommendation and a personal statement. More information about the program is available by visiting https://ag.purdue.edu/biochem/Pages/REU.aspx, or by contacting the PI (Dr. James Forney at forney@purdue.edu).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.