REU Site: A Multidisciplinary Research Experience in Engineered Bioactive Interfaces and Devices

为期三年的REU站点：肯塔基大学工程生物活性界面和设备的多学科研究经验将为工程生物活性界面和设备领域的大二，大三和大四本科生提供研究和教育经验。该领域专注于与生物系统相互作用并促进预期反应的建筑的新设计。这些先进的结构有许多应用，包括组织工程、传感系统和药物输送。学生将从各种本科学科中招收，包括工程、生物、化学、物理和数学，这些学科来自众多没有这些学科研究生课程的地方学院和大学。将作出特别努力，在少数民族机构和少数民族和妇女组织的全国会议上征聘人员，例如妇女工程师协会和全国黑人工程师协会。学生将与教师和研究生密切合作。具体目标包括：1)通过参与与工程生物活性界面和设备相关的研究项目，为学生提供真正的跨学科指导和研究培训；2)通过研讨会、实地考察以及与研究生和教师的互动，激发学生对科学和工程博士职业的兴趣；3)通过参与研究，培养学生的独立性和自信心。杂志俱乐部，内部演讲和科学会议。为期三年的REU站点：肯塔基大学工程生物活性界面和设备的多学科研究经验将为工程生物活性界面和设备领域的大二，大三和大四本科生提供研究和教育经验。长期以来，研究生物系统的研究人员和创造新型工程合成结构的研究人员之间的跨学科互动的需求一直被认为是一个重要的研究领域。这些先进的结构有许多应用，从组织工程到传感系统，再到药物输送，这些系统的成功开发不仅取决于通过纳米技术、自组装和混合系统开发新型合成结构的专业知识，还取决于这些界面与生物系统（如细胞和蛋白质）的相互作用。本课程将向学生介绍这个令人兴奋的多学科领域，他们将有机会学习三个跨学科的研究主题，这些主题构成了研究的基础1)“新型生物活性结构”，2)“细胞/蛋白质界面相互作用”，以及3)“集成到设备”。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The three-year REU Site: A Multidisciplinary Research Experience in Engineered Bioactive Interfaces and Devices at the University of Kentucky will provide research and education experience for rising sophomore, junior and senior undergraduates in the area of Engineered Bioactive Interfaces and Devices. This area focuses on the novel design of architectures that interact with biological systems and promote a desired response. These advanced architectures have numerous applications including tissue engineering, sensing systems, and drug delivery. Students will be recruited from various undergraduate disciplines including engineering, biology, chemistry, physics and mathematics from numerous regional colleges and universities that have no graduate programs in these disciplines. Special efforts will be made to recruit at minority institutions and national meetings of minority and women organizations such as the Society of Women Engineers and the National Society of Black Engineers. Students will work closely with faculty and graduate students. Specific objectives include 1) providing the students with true interdisciplinary mentoring and research training through their participation in a research project related to Engineered Bioactive Interfaces and Devices 2) stimulating the students’ interests in Ph.D. careers in science and engineering through seminars, field trips, and interactions with both graduate students and faculty, and 3) developing the students’ independence and confidence through participation in research, journal clubs, in house presentations and scientific meetings. The three-year REU Site: A Multidisciplinary Research Experience in Engineered Bioactive Interfaces and Devices at the University of Kentucky will provide research and education experience for rising sophomore, junior and senior undergraduates in the area of Engineered Bioactive Interfaces and Devices. The need for this cross-disciplinary interaction between investigators working on biological systems and those creating novel engineered synthetic architectures has long been recognized and emphasized as an important area of research. These advanced architectures have numerous applications ranging from tissue engineering, to sensing systems, to drug delivery and successful development of these systems will depend on expertise not only in developing novel synthetic architectures through nanotechnology, self-assembly and hybrid systems but also on the interactions of these interfaces with biological systems such as cells and proteins. This program introduces students to this exciting multidisciplinary area where they will have the opportunity to learn about three cross-disciplinary research themes that form the foundation of the research 1) “Novel Bioactive Architectures”, 2) “Cell/Protein Interactions at Interfaces”, and 3) “Integration into Devices”.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.