SBIR Phase I: Insu Health Design: Temperature Control System

这个第一期项目的更广泛影响/商业潜力是为大幅度改善温控储存和运输系统提供新的机会。这项技术有潜力成为理想的温度敏感药物储存解决方案，通过提供可靠的手段来保护和长期冷藏温度敏感的生物材料，如药物、血液、器官、疫苗、化学品和激素，甚至在缺乏或不稳定电力供应的地区，也能促进美国公众和第三世界国家的健康和福利。该无线技术领域的项目涉及无线和蓝牙通信技术的集成，用于数据捕获和传输，以进一步支持各种应用和服务，同时保持系统的完全移动性和较长的电池寿命。目前，全球有超过1亿人在使用200多种不同的温度敏感药物，拟议的创新可以为个人节省资金，并减少全球生物制药行业每年因温控物流失败而造成的350亿美元损失。这个小型企业创新研究（SBIR）第一阶段项目解决了在不受环境条件和电网可用性影响的情况下长时间保持便携式体积在精确温度范围内的问题。拟议研究的目标侧重于创新便携式体积的传热设计，通过建立概念验证可以实现有意义的性能改进，这些概念验证将在以后为医疗保健行业和冷链运输部门提供更好的解决方案，并使先进产品的生产成为可能。研究计划包括开发冷却系统内特定组件的多种设计，使用我们的平台测试它们各自对性能的影响，并量化冷藏效率和温度精度，以实现长期稳定性。预期的技术结果是经过测试的系统设计，具有强大的概念验证平台，可以用数据展示该技术，以支持该新技术的进一步开发，从而准备将产品推向市场。该公司还将收集数据，以更广泛地了解该技术在其他潜在市场的可扩展性。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this Phase I project is to offer novel opportunities to substantially improve temperature-controlled storage and transportation systems. The technology has the potential to become the ideal temperature-sensitive medication storage solution available to advance the health and welfare of the American public and third world countries by enabling a reliable means to protect and long-term refrigerate temperature-sensitive biomaterials such as medicines, blood, organs, vaccines, chemicals, and hormones even in areas that lack or have an unstable power supply. This project within the wireless technology area involves the integration of wireless and Bluetooth communication technologies for data capture and transmission to further support a wide variety of applications and services while maintaining full mobility, and long battery life for the system. Currently, there are over 200 different temperature-sensitive medications used by over 100 million people worldwide that the proposed innovation could provide monetary savings for individuals as well as decrease the $35 billion annual loss in the global biopharmaceutical industry due to failures in temperature-controlled logistics. This Small Business Innovation Research (SBIR) Phase I project tackles the problem of keeping a portable volume within a precise temperature range for extended periods regardless of ambient conditions and power grid availability. The objective of the proposed research focuses on innovating the heat transfer design in portable volumes where meaningful performance improvement can be achieved through building proofs-of-concept that will later inform and enable the production of advanced products that create better solutions in the healthcare industry and cold chain transportation sector. The research plan consists of developing multiple designs of specific components within the cooling system, testing their respective effects on performance using our platform, and quantifying the cold storage efficiency and temperature precision for long-term stability. The anticipated technical result is a tested system design with a robust proof of concept platform demonstrating the technology with data to support further development of this new technology for a product ready to bring to market. The company will have also gathered data for a broader understanding of the technology’s scalability in other potential markets.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.