MRI: Acquisition of a Gel Permeation Chromatography System with Dynamic Light Scattering Capabilities to Advance Research and Instructional Activities at Murray State University

MRI：采购具有动态光散射功能的凝胶渗透色谱系统，以推进默里州立大学的研究和教学活动

• 批准号: 2215040
• 负责人: Kevin Miller
• 金额: $ 22.36万
• 依托单位: Murray State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2215040&HistoricalAwards=false
• 关键词: MRI; Acquisition; Gel; Permeation; Chromatography

This award is jointly supported by the Major Research Instrumentation, the Established Program to Stimulate Competitive Research (EPSCoR), and the Chemistry Research Instrumentation Programs. Murray State University is acquiring a gel permeation chromatography system with dynamic light scattering detection (GPC/DLS) to support the research of Professor Kevin Miller and colleagues Gary Stinchcomb, Bikram Subedi, Christopher Lennon, and Grace Eder. This instrument facilitates research in the areas of chemistry, biological sciences, and Earth and environmental sciences. GPC separates molecules as a function of size based on their elution from a packed column. DLS is subsequently used, in-line, to measure time-dependent fluctuations in scattered light, which is related to molecular diffusion coefficeints and their size distributions. This instrument enhances the educational, research, and teaching efforts of students at all levels in many departments as well as provides accessibility for use at nearby institutions. The instrument is leveraged in research training opportunities in polymer chemistry, molecular biology, and environmental science. Students gain hands-on experience with the instrument through its integration in various courses.The award of the GPC/DLS is aimed at enhancing research and education at all levels, especially in areas such as polymer chemistry, molecular biology, and environmental science. Research focuses on molecular weight analysis of ionenes and cellulose functionalized with ionic liquids and poly(ionic liquids). Other investigations include the separation and analysis of drug residues and other small molecules from biological tissue, environmental samples, and wastewater. It also assists in analyzing molecular weight distributions of copolymers for organic photovoltaics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由重大研究仪器、既定的激励竞争研究计划(EPSCoR)和化学研究仪器计划共同支持。默里州立大学正在获得一种具有动态光散射检测(GPC/DLS)的凝胶渗透色谱系统，以支持Kevin Miller教授及其同事Gary Stinchcomb、Bikram Subedi、Christopher Lennon和Grace Eder的研究。该仪器促进了化学、生物科学、地球和环境科学领域的研究。GPC根据分子从填充柱中洗脱出来的大小来分离分子。随后，DLS被用于在线测量散射光中随时间变化的波动，这与分子扩散系数及其尺寸分布有关。这一工具加强了许多部门各级学生的教育、研究和教学努力，并提供了在附近机构使用的便利条件。该仪器在聚合物化学、分子生物学和环境科学的研究培训机会中发挥杠杆作用。学生通过将仪器集成在不同的课程中获得实践经验。GPC/DLS的获奖旨在加强所有级别的研究和教育，特别是在聚合物化学、分子生物学和环境科学等领域。研究的重点是离子液体和聚离子液体功能化的离子烯和纤维素的分子量分析。其他研究包括从生物组织、环境样本和废水中分离和分析药物残留和其他小分子。它还帮助分析用于有机光伏的共聚物的分子量分布。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。