MRI: Acquisition of a Confocal Raman Microscope for Multidisciplinary Research at Oakland University

MRI：奥克兰大学购买共焦拉曼显微镜进行多学科研究

• 批准号: 2216076
• 负责人: Ankun Yang
• 金额: $ 31.5万
• 依托单位: Oakland University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2216076&HistoricalAwards=false
• 关键词: MRI; Acquisition; Confocal; Raman; Microscope

Non-technical Description:This Major Research Instrumentation award acquires a confocal Raman spectrometer to support research, education, and outreach activities at Oakland University (OU). A Raman spectrometer is an optical instrument that measures vibrations of atoms in molecules and materials. It performs non-invasive materials characterizations with high spatial and spectral resolutions, supports existing research activities, and enables new research directions across disciplines from chemistry, physics, biological science to materials science pursued by researchers at OU. The Raman instrument provides research training and education opportunities for undergraduate and graduate students through research projects, curriculum, and laboratory sessions, and is integrated into outreach activities to help under-represented community members excel in science, technology, engineering, and mathematics. Located at OU, this advanced Raman instrument also provides research and educational opportunities to nearby universities and industry, and promotes research collaborations.Technical Description:Raman spectroscopy analyzes the inelastic scattering between incident photons and vibrations of molecules and materials, determines their vibrational modes, and provides a structural fingerprint by which molecules and materials can be identified. The acquired Raman instrument supports a wide range of research topics at OU spanning battery materials, chemical and biosensors, two-dimensional magnet and magnetism, mineral-organic interactions, to organic electronics. The advanced features of this Raman instrument include (i) confocal Raman with high spatial and spectral resolutions (0.5 micrometer and 0.2 cm-1); (ii) electrochemical cells with optical windows; (iii) a cooling and heating stage working from 77 K to 873 K; and (iv) photoluminescence measurement capability from visible to near-infrared (up to 2000 nm). These characteristics enable fundamental research, from understanding the electrochemical processes at electrode-electrolyte interfaces for high energy density batteries and greenhouse gas sensors, to investigation of hybrid magnonics phenomena for future quantum transduction systems and devices.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

非技术描述：该主要研究仪器奖获得了共焦拉曼光谱仪，以支持奥克兰大学（Oakland University）的研究，教育和推广活动。拉曼光谱仪是一种测量分子和材料中原子振动的光学仪器。它以高空间和光谱分辨率执行非侵入性材料表征，支持现有的研究活动，并使跨学科的新研究方向，从化学，物理，生物科学到材料科学，由研究人员追求。该拉曼仪器通过研究项目，课程和实验室会议为本科生和研究生提供研究培训和教育机会，并融入推广活动，以帮助代表性不足的社区成员在科学，技术，工程和数学方面表现出色。这台先进的拉曼光谱仪坐落在伦敦，为附近的大学和工业提供了研究和教育的机会，并促进了研究合作。技术描述：拉曼光谱分析入射光子与分子和材料振动之间的非弹性散射，确定其振动模式，并提供结构指纹，通过该指纹可以识别分子和材料。收购的拉曼仪器支持广泛的研究课题，涵盖电池材料，化学和生物传感器，二维磁体和磁性，矿物-有机相互作用，有机电子学。该拉曼仪器的先进功能包括：（i）具有高空间和光谱分辨率（0.5微米和0.2 cm-1）的共焦拉曼;（ii）具有光学窗口的电化学电池;（iii）在77 K至873 K范围内工作的冷却和加热台;以及（iv）从可见光到近红外（高达2000 nm）的光致发光测量能力。这些特性使基础研究成为可能，从了解高能量密度电池和温室气体传感器的电极-电解质界面的电化学过程，到研究未来量子转换系统和设备的混合磁振子现象。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Genetic analysis of human RNA binding motif protein 48 (RBM48) reveals an essential role in U12-type intron splicing

• DOI: 10.1093/genetics/iyac129
• 发表时间: 2022-08-30
• 期刊: GENETICS
• 影响因子: 3.3
• 作者: Siebert，Amy E.;Corll，Jacob;Lal，Shailesh
• 通讯作者: Lal，Shailesh