MRI: Acquisition of a Zeiss LSM900 Confocal Microscope with Airyscan 2 to Accelerate Multidisciplinary Research and Training

授予纽约皇后学院一个奖项，奖励其为成像、细胞和分子生物学核心设施购买一台带有Airyscan的Zeiss LSM 900共聚焦显微镜。有一个关键的需要，以支持教师和学生的研究生产力的机构，教育本科生谁将成为下一代的科学家和科学素养的公民。使这些机构的教师能够继续从事他们的科学专业领域，确保学生的教育和培训是充满活力的，受欢迎的和相关的。小型实验室小组促进了指导关系，并以与大型小组互补的方式为科学知识做出贡献。该项目将支持对皇后学院的学生和实习生群体产生积极影响的活动，并加强邻近机构的科学基础设施。皇后学院的学生，教师和管理人员种族多样。它们长期致力于向得不到充分服务的人口提供服务。蔡司LSM 900共聚焦显微镜的收购将提高教师的专业知识。研究结果将在研讨会和同行审查的出版物中传播。国家的最先进的显微镜将使一个新的显微镜课程的设计和执行高层次的本科生，硕士和博士生。该项目将通过与现有的大学项目合作，加强代表性不足的群体的STEM外联活动，旨在促进代表性不足的学生对STEM的接触和兴趣。显微镜的图像将用于学院的公共宣传活动，包括Twitter宣传和指导高中生。Zeiss LSM 900 Airyscan共聚焦显微镜的选择是因为它的特定功能满足了学院研究项目所需的细胞成像挑战，其用户界面和软件与该机构的其他设备相似，以及其灵活性，以满足预期的未来需求，随着研究计划的增长，新的教师被雇用，并形成合作。该仪器将被安置在成像，细胞和分子生物学的多用户核心设施，并将加强校园内不断增长的多学科科学研究，并丰富本科生和研究生的培训在这个少数民族服务机构。核心设施为用户提供服务，包括皇后学院生物学，化学和生物化学，地球和环境科学，物理学和心理学系的实验室。研究活动将包括对正常发育和生理学中的细胞信号传导、细胞防御机制、基因表达调控、学习的神经机制以及慢性疼痛对大脑的影响的研究。该仪器将使皇后学院的教师能够进行前沿研究，并在定性和定量荧光成像方面对本科生和研究生进行培训，这将提高他们的教育水平，为未来在生物科学领域的职业生涯做好准备。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

An award is made to Queens College of The City University of New York for the purchase of a Zeiss LSM 900 Confocal Microscope with Airyscan for the Core Facility for Imaging, Cell, and Molecular Biology. There is a critical need to support faculty and student research productivity at institutions that educate undergraduate students who will become the next generation of scientists and science-literate citizens. Enabling faculty at these institutions to remain engaged in their scientific fields of expertise ensures that student education and training is vibrant, welcoming, and relevant. Small laboratory groups facilitate mentoring relationships and contribute to scientific knowledge in ways that are complementary to those achieved in larger groups. This project will support activities that will positively impact the student and trainee populations at Queens College and enhance the scientific infrastructure for neighboring institutions. Queens College students, faculty, and administrators are ethnically diverse. They have a long-standing commitment to providing access to underserved populations. The acquisition of a Zeiss LSM 900 confocal microscope will enhance the faculty’s expertise. Research results will be disseminated in seminars and peer-reviewed publications. The state-of-the-art microscope will enable the design and execution of a new microscopy course for upper-level undergraduates, master’s and doctoral students. This project will strengthen STEM outreach activities of underrepresented groups through collaboration with existing college programs that aim to promote access to and interest in STEM for underrepresented students. Images from the microscope will be used in the public outreach activities of the faculty, which include Twitter outreach, and mentoring high school students.The Zeiss LSM 900 Confocal Microscope with Airyscan was selected for its specific features that meet the challenges of cellular imaging required by the faculty’s research programs, for the similarity of its user interface and software with other equipment at the institution, and for its flexibility to meet anticipated future needs as research programs grow, new faculty are hired, and collaborations are formed. The instrument will be housed in the multi-user Core Facility for Imaging, Cell and Molecular Biology and will enhance the growing multidisciplinary scientific research on campus and enrich undergraduate and graduate student training at this minority-serving institution. The Core Facility serves users that include laboratories in the Biology, Chemistry and Biochemistry, Earth and Environmental Sciences, Physics, and Psychology Departments at Queens College. Research activities will include investigations on cell signaling in normal development and physiology, cell defense mechanisms against aging and cancer, regulation of gene expression, neural mechanisms of learning, and the effects of chronic pain on the brain. The instrument will enable Queens College’s faculty to conduct cutting edge research and train undergraduates and graduate students in qualitative and quantitative fluorescent imaging, which will enhance their education and preparation for future careers in the biological sciences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.