Travel Support for Orthopedic Research Society (ORS) Musculoskeletal Biology Workshop; Snowbird, Utah; 23-27 July 2022

该奖项将为初级研究人员提供差旅支持，以参加2022年7月23-27日在犹他州雪鸟举行的第49届整形外科研究学会(ORS)肌肉骨骼(MSK)生物研讨会年会。这些讲习班促进了生物学家、工程师和临床医生在肌肉骨骼生物学、生物力学和机械生物学领域的跨学科交流；促进了各级研究人员在其职业生涯中的互动；建立了终身科学网络；强调初级教员和学生的积极参与；并且在讨论时间等于或超过分配给陈述的时间方面是独一无二的。研讨会的重点是广泛的、高度多学科的。会议讨论了当前的重大问题、局限性、潜在的解决方案和适用于基础科学和临床的方法。参加这一讲习班的有相当数量的学生、青年调查人员、妇女和代表性不足的少数群体。与ORS的伙伴关系通过广播电子邮件和ORS网站上的链接提供最大的可见度，摘要将张贴在网站上。2022年研讨会的科学主题是《肌肉骨骼免疫学和机械转导：从干细胞到衰老细胞的生物学和疾病》。该计划包括题为“骨骼和肌肉损耗的生物学”的RIB全体讲座；两次职业发展会议；以及六次科学会议：(1)主要方法：肌肉骨骼组织的光学成像；(2)骨科问题：肌肉骨骼疾病的自体-自体治疗；(3)免疫系统与肌肉骨骼组织之间的相互作用；(4)肌肉骨骼组织的机械生物学；(5)骨细胞：从生物学到病理生理学；以及(6)衰老中的问题：肌肉骨骼疾病的敏感疗法的发展。MSK研讨会的具体目标是(1)致力于分子、细胞、组织和生物力学过程的多学科基础和临床综合，以了解肌肉骨骼疾病的发病机制、预防和治疗。(2)将基础科学概念应用于临床问题，发展基础研究人员和临床研究人员之间的对话。(3)找出问题，制定解决肌肉骨骼疾病的方案。(4)为培训的学生和初级调查人员提供一个相互交流和与更资深科学家互动的论坛。该奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The award will provide travel support for junior investigators to attend the 49th annual meeting of the Orthopedic Research Society (ORS) Musculoskeletal (MSK) Biology Workshop in Snowbird, Utah, 23-27 July 2022. These workshops promote interdisciplinary communication between biologists, engineers, and clinicians in the area of musculoskeletal biology, biomechanics and mechanobiology; stimulate interactions among investigators in all levels in their careers; builds for-life scientific networks; emphasize active participation of junior faculty and students; and are unique in that discussion time equals or exceeds time allotted for presentations. The focus of the workshop is broad and highly multidisciplinary. Sessions address significant current problems, limitations, potential solutions, and approaches applicable to both basic science and clinical. The attendance of this Workshop represents a significant number of students, young investigators, women, and underrepresented minorities. Partnership with the ORS provides maximum visibility through broadcast emails and links on the ORS website, where abstracts will be posted. The scientific theme of the 2022 workshop is “Musculoskeletal immunology and mechanotransduction: biology and disease from stem to senescent cells.” The program consists of the “Remodeling in Bone” (RIB) plenary lecture entitled “The biology of bone and muscle wasting”; two career development sessions; and six scientific sessions: (1) Major Methodologies: Optical imaging of musculoskeletal tissues; (2) Problems in Orthopaedics: Autologous-autogenous treatments for musculoskeletal disease; (3) Interactions between the immune system and musculoskeletal tissues; (4) Mechanobiology of musculoskeletal tissues; (5) Osteocytes: From biology to pathophysiology; and (6) Problems in Aging: Development of senolytic therapies for musculoskeletal disorders. The specific objectives of the MSK workshops are (1) Work toward a multidisciplinary basic and clinical synthesis of molecular, cellular, tissue, and biomechanical processes that lead to understand the pathogenesis of musculoskeletal diseases, prevention, and treatment. (2) Apply basic science concepts to clinical problems and develop dialogue between basic and clinical investigators. (3) Identify problems and formulate solutions to musculoskeletal diseases. (4) Provide a forum for students and junior investigators training to interact among themselves and with more senior scientists.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.