Workshop on Musculoskeletal Biology at the 50th Annual Meeting of the Orthopedic Research Society; Midway, Utah; 22-27 July 2023

该奖项将为初级研究人员提供旅行支持，参加骨科研究学会（ORS）第50届年会上的肌肉骨骼生物学研讨会;中途岛，犹他州; 2023年7月22日至27日。该研讨会促进生物学家，工程师和临床医生在肌肉骨骼生物学，生物力学和机械生物学领域的跨学科交流;刺激各级职业调查人员之间的互动;建立终身科学网络;强调初级教师和学生的积极参与;并且在讨论时间等于或超过分配给演示的时间方面是独一无二的。讲习班的重点是广泛的和高度多学科的。会议解决当前的重大问题，局限性，潜在的解决方案，以及适用于基础科学和临床的方法。参加这次讲习班的有相当多的学生、年轻调查人员、妇女和代表性不足的少数民族。与ORS的合作伙伴关系通过广播电子邮件和ORS网站上的链接提供了最大的可见度，其中摘要将被张贴。2023年研讨会的科学主题是“肌肉骨骼细胞：身份，靶向，刺激和操纵以获得治疗收益。会议将讨论当前的重大问题，局限性和潜在的解决方案，以及适用于临床和基础科学的方法。全体讲座“骨重塑”（RIB）的标题是“骨机械生物学：利用骨骼负荷的力量。”六个科学会议将涵盖（1）从单细胞组学技术对骨关节炎发病机制的新见解;（2）骨骼干细胞/祖细胞;（3）工作中的成像机械生物学;（4）破骨细胞：起源和命运;（5）结缔组织靶向：将分子传递到肌肉骨骼组织;（6）骨关节炎的发病机制。以及（6）罕见骨和矿物质疾病的分子病理生理学如何为治疗和生物学提供信息。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准。

This award will provide travel support for junior investigators to attend the Workshop on Musculoskeletal Biology at the 50th Annual Meeting of the Orthopedic Research Society (ORS); Midway, Utah; 22-27 July 2023. This workshop promotes interdisciplinary communication among biologists, engineers, and clinicians in the area of musculoskeletal biology, biomechanics and mechanobiology; stimulates interactions among investigators in all levels in their careers; builds for-life scientific networks; emphasizes active participation of junior faculty and students; and is unique in that discussion time equals or exceeds time allotted for presentations. The focus of the workshop is broad and highly multidisciplinary. Sessions address significant current problems, limitations, potential solutions, and approaches applicable to both basic science and clinical. The attendance of this Workshop represents a significant number of students, young investigators, women, and underrepresented minorities. Partnership with the ORS provides maximum visibility through broadcast emails and links on the ORS website, where abstracts will be posted.The scientific theme of the 2023 workshop is "Musculoskeletal cells: identity, targeting, stimulation, and manipulation for therapeutic gain." Sessions will address significant current problems, limitations and potential solutions, and approaches applicable to both clinical and basic science. The Plenary Lecture “Remodeling in Bone” (RIB) is entitled “Bone mechanobiology: harnessing the power of skeletal loads.” Six scientific sessions will cover (1) New insights into osteoarthritis pathogenesis from single-cell -omic technologies; (2) Skeletal stem/progenitor cells; (3) Imaging mechanobiology at work; (4) Osteoclasts: origin and fate; (5) Connective tissue targeting: delivering molecules to musculoskeletal tissues; and (6) How the molecular pathophysiology of rare bone and mineral diseases informs treatment and biology.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.