The Interrelationship Between Friction and Fracture in Needle Insertion

进针时摩擦与断裂的相互关系

• 批准号: 2219787
• 负责人: Shelby Hutchens
• 金额: $ 64.07万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2219787&HistoricalAwards=false
• 关键词: Interrelationship; Between; Friction; Fracture; Needle

This award will advance understanding of the fundamental mechanics of needle insertion. Despite the ubiquity of needle-based medical procedures and a wealth of needle insertion studies, there are critical gaps in understanding. Quantification of the sliding friction and material fracture during post-puncture needle insertion is needed to evaluate new needle designs and the soft materials into which they may be inserted. The current shortcomings in computational prediction stem in part from a missing description of the effect of friction and fracture on one another. A more detailed understanding is critical to the successful expansion of minimally invasive methods to areas beyond the body’s surface. Successful description of the fundamental mechanics of these effects will both facilitate control schemes and enable rapid evaluation of novel needle designs. This research is expected to ultimately result in reduced patient discomfort, healing time, and procedure costs. This research will be implemented with a team of graduate researchers who will receive management training to coordinate the effort of undergraduate trainees. The researchers will share their experiences and findings via social media with the aim of illuminating the challenges, rewards, and process of mechanics of materials research for the public.This research will quantify the simultaneous and reciprocal effects of sliding friction and material rupture during post-puncture needle insertion. Initial goals will guide the work toward first understanding the influence of fracture on surface morphology and the latter’s influence on friction. Once gained, these separate effects will be unified in the primary goal of simultaneously describing interfacial mechanics along the needle shaft and fracture at the needle tip. Tests will be performed at quasi-static to surgically-relevant rates. First, surface damage morphology will be systematically varied by controlling both the energy available to fracture (via tip radius and boundary conditions in planar and needle geometries) and material constitutive response using two well-characterized materials systems typical of needle insertion studies, but having different failure behaviors: oil-diluted silicone (tougher) and hydrogel (more brittle). Second, the effect of surface damage morphology on frictional resistance to sliding will be measured to establish correlations and critical regimes as a function of rate and normal force. Finally, using these correlations, planar cutting geometry conditions will be mapped to the cylindrical needle-insertion geometry to quantify frictional effects which will be further tuned via surface modification. This mapping will be initiated via local failure criteria obtained from full field strain measurement during in situ needle insertion and cutting. The resulting fundamental understanding of the interrelationship between friction and fracture will inform the development of more robust computational models of needle insertion and lead to more refined and improved models for robotic needle insertion. Both advances will enhance the development of minimally-invasive, tissue-specific needle designs.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这一奖项将增进对针插入的基本机制的理解。尽管基于针头的医疗程序无处不在，也有大量的针头插入研究，但在理解上仍存在严重差距。需要量化穿刺针插入过程中的滑动摩擦和材料断裂，以评估新的针设计和可以插入的软材料。目前计算预测的缺陷部分源于对摩擦和断裂相互影响的描述缺失。更详细的了解对于成功地将微创方法扩展到人体表面以外的区域至关重要。成功地描述这些效应的基本机制将有助于控制方案，并使新的针设计能够快速评估。这项研究有望最终减少患者的不适感、愈合时间和手术成本。这项研究将与一组研究生研究人员一起实施，他们将接受管理培训，以协调本科生的努力。研究人员将通过社交媒体分享他们的经验和发现，目的是向公众阐明材料力学研究的挑战、回报和过程。这项研究将量化穿刺针插入过程中滑动摩擦和材料断裂的同时和相互影响。最初的目标将引导这项工作首先了解断裂对表面形态的影响，以及后者对摩擦的影响。一旦获得，这些单独的效应将统一为同时描述沿针轴的界面力学和针尖断裂的主要目标。测试将以与手术相关的准静态速率进行。首先，表面损伤形态将通过控制可用于断裂的能量(通过平面和针尖几何形状中的尖端半径和边界条件)和材料本构响应来系统地改变，使用两种典型的具有良好特征的材料系统进行针插入研究，但具有不同的破坏行为：油稀释硅胶(更坚韧)和水凝胶(更脆)。其次，将测量表面损伤形态对滑动摩擦阻力的影响，以建立作为速率和法向力的函数的相关性和临界状态。最后，利用这些相关性，平面切割几何条件将被映射到柱面针插入几何形状，以量化摩擦效应，并将通过表面修改进一步调整。这种映射将通过在原位插针和切割过程中通过全场应变测量获得的局部失效标准来启动。由此产生的对摩擦和骨折之间相互关系的基本理解将有助于开发更健壮的针头插入计算模型，并导致更精细和改进的机器人针头插入模型。这两项进展都将促进微创、组织特异性针头设计的发展。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。