Research Infrastructure: Sustaining the ABRC: Arabidopsis genomic and genetic seed and DNA stocks

研究基础设施：维持 ABRC：拟南芥基因组和遗传种子及 DNA 库存

• 批准号: 2221747
• 负责人: David Somers
• 金额: $ 100.78万
• 依托单位: Ohio State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2221747&HistoricalAwards=false
• 关键词: Research; Infrastructure; Sustaining; ABRC; Arabidopsis

A new award is made to Ohio State University to support the Arabidopsis Biological Resource Center (ABRC). The ABRC mission is to collect, preserve, reproduce, and distribute resources related to the plant Arabidopsis thaliana (Arabidopsis) for use in research and education. Arabidopsis is an important plant model and results from Arabidopsis research inform research and development in other living systems including crop plants, animals, and even humans. The ABRC maintains a collection of over a million resources derived from Arabidopsis and closely related plants. Important and frequently requested resources include seed lines collected from around the world representing the full spectrum of natural variation in Arabidopsis, and seed lines with induced mutations in almost every Arabidopsis gene for investigating gene function. These resources were developed by researchers in the US and around the world and are catalogued and stored in optimal conditions. The ABRC actively promotes the use of Arabidopsis in plant science education. Local K-12 students are served via in-school programming and field trips to ABRC laboratories and growth facilities. Teachers utilizing Greening the Classroom and TRAINED education kits, or using Arabidopsis to develop their own protocols, receive in-person or remote support. Public outreach includes participation in WestFest, a science and sustainability festival hosted at The Ohio State University, as well as activity booths at The Ohio State Fair, and the Big Science Celebration festival at the Columbus science museum, Center of Science and Industry (COSI).The ABRC’s long-term goals are: 1) to provide cutting-edge biological resources to the Arabidopsis and broader plant science community at an accessible price, 2) to maintain the existing collection to ensure continued access to high quality resources, 3) to continue to add to the collection though acquisition of Arabidopsis resources projected to be highly requested and new types of resources based on the needs of the community, 4) to provide free access to curated stock information, and 5) to continue the role of ABRC as a resource for education and outreach. Materials and bioinformatic information supplied by the ABRC to the plant research community ensure adequate resources are available worldwide and offers the most comprehensive Arabidopsis seed and DNA stocks in the world. The ABRC maintains a web site, accessed by approximately 2,000 users per week, providing access to information and a platform for ordering Arabidopsis resources. Close to 100,000 samples are shipped each year to researchers and educators in the US and 82 other countries.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

俄亥俄州立大学获得了一项新的奖项，以支持拟南芥生物资源中心（ABRC）。ABRC的使命是收集、保存、繁殖和分发与拟南芥（Arabidopsis thaliana）有关的资源，用于研究和教育。拟南芥是一种重要的植物模型，拟南芥研究的结果为包括作物植物、动物甚至人类在内的其他生命系统的研究和开发提供了信息。ABRC保存了来自拟南芥及其密切相关植物的100多万种资源。重要和经常要求的资源包括从世界各地收集的种子系，代表了拟南芥自然变异的全谱，以及几乎每个拟南芥基因诱导突变的种子系，用于研究基因功能。这些资源是由美国和世界各地的研究人员开发的，并在最佳条件下进行分类和存储。ABRC积极推广拟南芥在植物科学教育中的应用。当地K-12学生通过校内编程和实地考察ABRC实验室和成长设施。教师利用“绿化教室”和经过培训的教育工具包，或利用拟南芥制定自己的协议，获得现场或远程支持。公众推广活动包括参加在俄亥俄州立大学举办的科学和可持续发展节WestFest，以及在俄亥俄州立博览会上的活动摊位，以及在哥伦布科学博物馆、科学与工业中心（COSI）举办的大科学庆典节。ABRC的长期目标是：1)以可接受的价格为拟南芥和更广泛的植物科学界提供前沿的生物资源，2)维护现有的馆藏以确保持续获得高质量的资源，3)通过获取预计需求量很大的拟南芥资源和基于社区需求的新类型资源，继续增加馆藏，4)免费提供整理的库存信息。5)继续发挥ABRC作为教育和外联资源的作用。ABRC向植物研究界提供的材料和生物信息学信息确保了世界范围内充足的资源，并提供了世界上最全面的拟南芥种子和DNA库存。ABRC拥有一个网站，每周约有2000名用户访问，提供信息访问和订购拟南芥资源的平台。每年有近10万个样本被运往美国和其他82个国家的研究人员和教育工作者手中。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。