Increasing the Efficiency of Biomolecular Simulations

提高生物分子模拟的效率

• 批准号: LX0882184
• 负责人: Prof Alan Mark
• 金额: $ 2.2万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage - International
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LX0882184
• 关键词: Increasing; Efficiency; Biomolecular; Simulations

This program will extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Australia at the forefront of developing simulation techniques in biomolecular systems, which are widely used within the chemical and pharmaceutical industries. It will also provide opportunities for the training and development of young Australian researchers with top European laboratories.

该计划将扩展生物分子系统的范围，可以以接近原子的精度建模。这将有助于更好地理解参与膜融合和裂变调节的蛋白质的结构和功能，以及揭示大规模蛋白质-蛋白质和蛋白质-膜复合物的组装。这项工作将有助于澳大利亚在开发生物分子系统模拟技术方面处于领先地位，这些技术广泛应用于化学和制药行业。它还将为在欧洲顶级实验室工作的年轻澳大利亚研究人员提供培训和发展的机会。