Structural biology of bacterial lipid II-glycopeptide antibiotic interactions

细菌脂质 II-糖肽抗生素相互作用的结构生物学

• 批准号: nhmrc : 1026922
• 负责人: Prof Alan Mark
• 金额: $ 40.35万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/structural-biology-bacterial-antibiotic-interactions/110526
• 关键词: Structural; biology; bacterial; lipid; II

Drug resistant bacteria are threatening our ability to successfully treat serious life-endangering infections, with many common antibiotics no longer effective. We will study in atomic detail how one class of antibiotics interacts with bacteria in order to design new members of this group that can overcome resistance.

耐药细菌正威胁着我们成功治疗严重危及生命的感染的能力，许多常见的抗生素已不再有效。我们将在原子细节上研究一类抗生素如何与细菌相互作用，以便设计出能够克服耐药性的新成员。