Planning: ANT LIA Planning an Antarctic Omics Initiative (AOI) to Advance Understanding of the Evolution and Adaptive Potential of Antarctic Organisms

规划：ANT LIA 规划南极组学计划 (AOI)，以加深对南极生物进化和适应潜力的了解

• 批准号: 2231468
• 负责人: Alison Murray
• 金额: $ 14.35万
• 依托单位: Nevada System of Higher Education, Desert Research Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2024-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2231468&HistoricalAwards=false
• 关键词: Planning; ANT; LIA; Antarctic; Omics

Life in Antarctica and the Southern Ocean is exceptionally susceptible to climate change. Understanding how Antarctic organisms and assemblages acclimate and adapt to climatic shifts and cascading impacts is essential to conservation efforts and forecasting critical changes. The blueprints of evolutionary history and the potential to adapt to environmental change are encoded in (meta)genomes. This project is a response to the National Academies of Science, Engineering and Medicine’s (NASEM) 2015 Strategic Vision for Antarctic and Southern Ocean Research vision of an Antarctic genomics initiative that would catalyze the science needed to decode the genomic and functional bases of adaptation in changing environments across the spectrum of Antarctic life. The project will convene a workshop to build consensus across a diverse community of life scientists to turn this vision into actionable proposals, and there is significant potential for the community building and planning activities to galvanize an Antarctic ‘Omics Initiative (AOI) that will have considerable impacts on society’s understanding of Antarctic life by engendering predictions of how it may evolve, resist, acclimate, or become susceptible to changes in climate. Societal benefits include engaging the scientific community across multiple disciplines, enhancing the diversity of Antarctic researchers, developing new expertise in Antarctic sciences, and fostering an informed public. The primary aim of this project is to realize the potential for making fundamental advances in understanding polar life and its inextricable links to survival and adaptation across Antarctica’s remarkably diverse ecosystems. The project will facilitate a results-driven workshop to create an implementation plan for making transformative advances in understanding Antarctic biota and assemblages and address large-scale, broad, ecosystem-based questions. They will foster an integrative understanding of biological adaptation to environmental change and the extreme ecosystems found in Antarctica and the Southern Ocean by utilizing cross-ecosystem, interdisciplinary comparative genomic approaches. The open-design workshop will engage researchers with expertise in executing large scale, integrated genomics programs, developing models for training, and engaging the next generation of polar scientists. By addressing these large-scale, broad, ecosystem-based questions, this project aims to build a sustainable, networked, international scientific community and engender ideas to serve as the foundation for an initiative that will accelerate knowledge gain and community building. The project aims to build a sustainable community of scientists by recruiting a diverse, inclusive cohort of participants. The participants will create a summary of contributions to date of ‘omics-inspired studies that have contributed to our understanding of Antarctic evolution and adaptation and synthesize the outcomes of the workshop in a report that will be available to NSF and the scientific community.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

南极洲和南大洋的生命特别容易受到气候变化的影响。了解南极生物和组合如何适应和适应气候变化和级联影响对于保护工作和预测关键变化至关重要。进化历史的蓝图和适应环境变化的潜力都编码在（Meta）基因组中。该项目是对美国国家科学、工程和医学院（NASEM）2015年南极和南大洋研究战略愿景的回应，该愿景是南极基因组学倡议，将促进解码南极生命在不断变化的环境中适应的基因组和功能基础所需的科学。该项目将召开一个研讨会，在不同的生命科学家社区建立共识，将这一愿景转化为可操作的建议，社区建设和规划活动有很大的潜力，以激发南极组学倡议（AOI），这将对社会对南极生命的理解产生相当大的影响。或者变得容易受到气候变化的影响。社会效益包括使科学界参与多个学科，提高南极研究人员的多样性，发展南极科学的新专门知识，并培养知情的公众。该项目的主要目的是实现在了解极地生命及其与南极洲极其多样化的生态系统的生存和适应之间不可分割的联系方面取得根本性进展的潜力。该项目将促进一个注重成果的讲习班，以制定一项执行计划，在了解南极生物区系和生物组合方面取得变革性进展，并解决大规模、广泛的生态系统问题。他们将通过利用跨生态系统、跨学科的比较基因组方法，促进对环境变化和南极洲和南大洋极端生态系统的生物适应的综合理解。开放式设计研讨会将吸引具有执行大规模综合基因组学项目、开发培训模型和吸引下一代极地科学家方面专业知识的研究人员。通过解决这些大规模的、广泛的、基于生态系统的问题，该项目旨在建立一个可持续的、网络化的国际科学界，并产生各种想法，作为一项加速知识获取和社区建设的倡议的基础。该项目旨在通过招募多元化、包容性的参与者群体，建立一个可持续的科学家社区。与会者将创建一个摘要的贡献，以日期'omics-对我们理解南极进化和适应做出贡献的启发性研究，并将研讨会的成果综合在一份报告中，该报告将提供给NSF和科学界。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查进行评估，被认为值得支持的搜索.