Collaborative Research: Conference: Workshop on Computational Structural Biology 2022

计算结构生物信息学研讨会(CSBW)是一个单轨、为期一天的研讨会，以同行评议的工作为特色，研究结构生物学中计算方法的进展。理解蛋白质和核苷酸结构在生命过程中的基本作用涉及到许多计算挑战。它是IEEE-生物信息学和生物医学的一部分。产生和使用大量结构数据的新的实验和计算技术使新的分析方法成为可能，从而增加了对不同生物物理现象的理解。CSBW为讨论与蛋白质结构发现和分析相关的最新计算方法提供了一个论坛。结构生物学是一个跨学科的领域，CSBW通过计算机科学、生物信息学、生物化学和计算生物学等不同学术领域的镜头将致力于这一主题的科学家联系起来。拟议的讲习班的主要目标之一是将本科生和研究生与计算生物信息学社区联系起来，使他们有机会向该领域的顶尖科学家展示他们的工作，并与他们的同行建立网络。这种互动对学生的学术生活产生了持久的影响，因为它们使学生接触到最先进的研究，并创造了职业发展所需的专业联系。拟议的研讨会将把资深研究人员和致力于通过计算结构生物信息学探索序列、结构和蛋白质功能之间的关系的学生聚集在一起。研讨会将展示各种问题和计算方法的最新进展，包括：结构表示、预测和比对、生物分子相互作用和对接、分子动力学模拟、生物分子图形学、粗粒度建模、结构数据的数据挖掘、结构基因组学、结构问题的优化、建模中的高性能计算、图论在结构问题中的应用以及生物分子结构的改进。来自不同背景的研究人员的参与将促进对共同科学主题的理解，并可能促进围绕共同研究目标的合作。接受研讨会的论文将在IEEE Xplore数字图书馆发表。研讨会参与者还将在同行评议的杂志上收到特别问题的邀请函。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

The Computational Structural Bioinformatics Workshop (CSBW) is a single-track, one-day workshop featuring peer-reviewed works on advances in computational methods in structural biology. Understanding the fundamental role of protein and nucleotide structures in life processes involves many computational challenges. It is held as part of the IEEE-Bioinformatics and Biomedicine. New experimental and computational techniques that generate and use large amounts of structural data have enabled novel analysis approaches, leading to an increased understanding of different biophysical phenomena. CSBW provides a forum for discussion of the newest computational approaches related to protein structure discovery and analysis. Structural biology is an interdisciplinary field, and CSBW connects scientists who work on this topic through the lens of various academic areas, such as computer science, bioinformatics, biochemistry, and computational biology. One of the main goals of the proposed workshop is to connect undergraduate and graduate students to the computational bioinformatics community, giving them an opportunity to present their work to top scientists in the field and to network with their peers. Such interactions have a lasting impact in a student’s academic life, as they expose students to state-of-the-art research and creates the professional connections needed for career advancement.The proposed workshop will bring together senior researchers and students working on exploring the relationships between sequence, structure and protein function via computational structural bioinformatics. The workshop will showcase the newest developments on a diverse set of problems and computational methods, including: Structure representation, prediction, and alignment, biomolecular interaction and docking, molecular dynamics simulations, biomolecular graphics, coarse-grained modeling, data mining of structural data, structural genomics, optimization in structural problems, high-performance computing in modeling, graph theory applied to structural problems, and biomolecular structure refinement. The participation of researchers from diverse backgrounds will advance understanding of common scientific themes and may facilitate collaborations around shared research goals. Papers accepted to the workshop will be published in IEEE Xplore Digital Library. Workshop participants will also receive invitations for a special issue in a peer-reviewed journal.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.