Collaborative Research: Conference: Large Language Models for Biological Discoveries (LLMs4Bio)

合作研究:会议:生物发现的大型语言模型 (LLMs4Bio)

基本信息

  • 批准号:
    2411529
  • 负责人:
  • 金额:
    $ 1.95万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2024
  • 资助国家:
    美国
  • 起止时间:
    2024-03-01 至 2025-02-28
  • 项目状态:
    未结题

项目摘要

Computational research on large language models (LLMs) is advancing rapidly and expanding beyond Natural Language Processing (NLP). In particular, there is great interest in how these models can be leveraged and advanced to enable scientific inquiry across scientific disciplines. This award will support the organization of a workshop focused on the utilization of LLMs for biological discoveries: LLMs4Bio accompanies the 2024 AAAI conference. The AAAI conference series has established itself as the world’s premier research conference in AI. This workshop addresses these challenges and brings together researchers from computer science, information science, and molecular, cellular, and systems biology to address unique challenges in advancing biological discoveries. This workshop activity will increase student participation in the 2024 AAAI Conference on Artificial Intelligence (AAAI) that will take place from Feb 22-28 in Vancouver, Canada, by providing travel grants to U.S.-based students. The AAAI conference series has established itself as the world’s premier research conference in AI. Outcomes include the formulation of new problem spaces, the inclusion of more researchers in the identified intersectional communities, and the catalysis of further innovation on accessible and inclusive LLMs to power the next scientific breakthroughs. A strong representation of US researchers at the conference also helps maintain US competitiveness in this important area.This workshop activity will provide an international forum for presentation of AI technological advancement and applications in societal areas. The conference covers all aspects of AI, including theories, algorithms, software, and systems, and applications. The award will support: i) “LLMs for biology” panel discussions, ii) paper presentation and Q&A interactions, iii) networking across NLP and biological domain experts, and iv) outlook of future opportunities of our communities. These activities will support students and young researchers as they prepare to advance their careers in scientific research, as well as broaden the participation of under-represented groups in computing and, in particular, in AI research. The current pace of research in LLMs makes it challenging for researchers to deeply understand scientific problems, community-acceptable standards, datasets, metrics, and benchmark tasks that truly capture our ability to advance on a problem, and precious knowledge gathered over decades of hard-fought research. The current trend of closed or poorly-described industry models that remain beyond resources typically available to academic researchers, often disseminated through non-peer reviewed platforms is also not conducive to cross-fertilization of research. This workshop addresses these challenges and brings together researchers from computer science, information science, and molecular, cellular, and systems biology to address unique challenges in advancing biological discoveries, such as standardized datasets, community-accepted benchmarks, experimental noise and uncertainty quantification, interpretation, and injection of prior biological knowledge. A Github project, https://github.com/LLMs4Science-Community, that accompanies the workshop activity provides a long-term platform for sharing workshop research articles, datasets, benchmarks, metrics, and other resulting knowledge for the workshop in this debut offering and other planned annual offerings.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
大型语言模型(LLM)的计算研究正在迅速发展,并超越了自然语言处理(NLP)。特别是,人们对如何利用和推进这些模型以实现跨学科的科学探究非常感兴趣。该奖项将支持组织一个专注于利用LLM进行生物发现的研讨会:LLMs 4 Bio伴随着2024年AAAI会议。AAAI系列会议已成为世界上首屈一指的人工智能研究会议。本次研讨会解决了这些挑战,并汇集了来自计算机科学,信息科学,分子,细胞和系统生物学的研究人员,以解决推进生物学发现的独特挑战。本次研讨会活动将增加学生参与2024年AAAI人工智能会议(AAAI),该会议将于2月22日至28日在加拿大温哥华举行,通过向美国提供旅行赠款。基于学生。AAAI系列会议已成为世界上首屈一指的人工智能研究会议。其成果包括制定新的问题空间,在确定的交叉社区中纳入更多的研究人员,以及催化可访问和包容性LLM的进一步创新,以推动下一个科学突破。美国研究人员在会议上的强大代表性也有助于保持美国在这一重要领域的竞争力。本次研讨会活动将提供一个国际论坛,介绍人工智能技术的进步和在社会领域的应用。会议涵盖了人工智能的各个方面,包括理论,算法,软件和系统以及应用。该奖项将支持:i)“LLM生物学”小组讨论,ii)论文演示和问答互动,iii)NLP和生物领域专家的网络,以及iv)我们社区未来机会的展望。这些活动将为学生和年轻研究人员提供支持,帮助他们准备推进科学研究事业,并扩大代表性不足的群体对计算,特别是人工智能研究的参与。LLM目前的研究速度使研究人员难以深入了解科学问题,社区可接受的标准,数据集,指标和基准任务,这些任务真正抓住了我们推进问题的能力,以及数十年来收集的宝贵知识。目前的趋势是封闭的或描述不佳的行业模型仍然超出了学术研究人员通常可用的资源,通常通过非同行评审的平台传播,这也不利于研究的交叉施肥。本次研讨会解决了这些挑战,并汇集了来自计算机科学,信息科学,分子,细胞和系统生物学的研究人员,以解决推进生物学发现的独特挑战,如标准化数据集,社区接受的基准,实验噪声和不确定性量化,解释和注入先前的生物学知识。Github项目,https://github.com/LLMs4Science-Community,伴随着研讨会活动,提供了一个长期的平台,用于分享研讨会的研究文章,数据集,基准,指标,以及其他由此产生的知识,为研讨会在这个首次提供和其他计划的年度提供。这个奖项反映了NSF的法定使命,并被认为值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估来支持。

项目成果

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Amarda Shehu其他文献

Molecules in motion: Computing structural flexibility
An Evolutionary Search Algorithm to Guide Stochastic Search for Near-Native Protein Conformations with Multiobjective Analysis
一种进化搜索算法,通过多目标分析指导随机搜索近天然蛋白质构象
Structure- and Energy-based Analysis of Small Molecule Ligand Binding to Steroid Nuclear Receptors
小分子配体与类固醇核受体结合的基于结构和能量的分析
On the characterization of protein native state ensembles.
关于蛋白质天然状态整体的表征。
  • DOI:
    10.1529/biophysj.106.094409
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
    Amarda Shehu;L. Kavraki;C. Clementi
  • 通讯作者:
    C. Clementi
From Optimization to Mapping: An Evolutionary Algorithm for Protein Energy Landscapes
从优化到映射:蛋白质能量景观的进化算法

Amarda Shehu的其他文献

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{{ truncateString('Amarda Shehu', 18)}}的其他基金

Collaborative Research: IIBR: Innovation: Bioinformatics: Linking Chemical and Biological Space: Deep Learning and Experimentation for Property-Controlled Molecule Generation
合作研究:IIBR:创新:生物信息学:连接化学和生物空间:属性控制分子生成的深度学习和实验
  • 批准号:
    2318829
  • 财政年份:
    2023
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Continuing Grant
Collaborative Research: IIS: III: MEDIUM: Learning Protein-ish: Foundational Insight on Protein Language Models for Better Understanding, Democratized Access, and Discovery
协作研究:IIS:III:中等:学习蛋白质:对蛋白质语言模型的基础洞察,以更好地理解、民主化访问和发现
  • 批准号:
    2310113
  • 财政年份:
    2023
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Standard Grant
Intergovernmental Personnel Act
政府间人事法
  • 批准号:
    1948645
  • 财政年份:
    2019
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Intergovernmental Personnel Award
Collaborative: SI2-SSE - A Plug-and-Play Software Platform of Robotics-Inspired Algorithms for Modeling Biomolecular Structures and Motions
协作:SI2-SSE - 用于生物分子结构和运动建模的机器人启发算法的即插即用软件平台
  • 批准号:
    1440581
  • 财政年份:
    2015
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Standard Grant
Travel Awards for 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM-2015)
2015 年 IEEE 国际生物信息学和生物医学会议 (BIBM-2015) 旅行奖
  • 批准号:
    1543744
  • 财政年份:
    2015
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Standard Grant
CCF: AF: Small: Novel Stochastic Optimization Algorithms to Advance the Treatment of Dynamic Molecular Systems
CCF:AF:Small:新型随机优化算法推进动态分子系统的治疗
  • 批准号:
    1421001
  • 财政年份:
    2014
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Standard Grant
Workshop: 2014 NSF CISE CAREER Proposal Writing Workshop
研讨会:2014 NSF CISE CAREER 提案写作研讨会
  • 批准号:
    1415210
  • 财政年份:
    2013
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Standard Grant
CAREER: Probabilistic Methods for Addressing Complexity and Constraints in Protein Systems
职业:解决蛋白质系统复杂性和约束的概率方法
  • 批准号:
    1144106
  • 财政年份:
    2012
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Continuing Grant
AF: Small: A Unified Computational Framework to Enhance the Ab-Initio Sampling of Native-Like Protein Conformations
AF:小型:增强类天然蛋白质构象从头开始采样的统一计算框架
  • 批准号:
    1016995
  • 财政年份:
    2010
  • 资助金额:
    $ 1.95万
  • 项目类别:
    Standard Grant

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合作研究:会议:生物发现的大型语言模型 (LLMs4Bio)
  • 批准号:
    2411530
  • 财政年份:
    2024
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    $ 1.95万
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    Standard Grant
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