REU Site: Comparative Animal Model Approaches to Regeneration and Aging

REU 网站:再生和衰老的比较动物模型方法

基本信息

  • 批准号:
    2243416
  • 负责人:
  • 金额:
    $ 40.97万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-04-01 至 2026-03-31
  • 项目状态:
    未结题

项目摘要

This REU Site award to the Mount Desert Island Biological Laboratory (MDIBL), located in Bar Harbor, ME, will support the training of 10 students for 10 weeks during the summers of 2023-2025. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities or from underrepresented groups, will be trained in the program. Students will be at all stages of their undergraduate studies, and special consideration will be given to applicants interested in microscopy and comparative animal model research on regeneration and aging. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. Assessment of the program will be done through the online SALG URSSA tool. Students will be required to register in the NSF ETAP system (etap.nsf.gov) and tracked after the program to determine their career paths.This REU program MDIBL will expose students to comparative animal model approaches used to understand the biology of regeneration and aging. Labs at this REU site are interested in how cells, tissues, organs, and limbs are repaired or replenished after injury or during the ordinary course of development and the mechanisms retained or reemployed to ensure an organism thrives once development is complete. To answer these questions, researchers at MDIBL use various animal models. These animals include zebrafish, killifish, axolotl, fruit flies (Drosophila), and nematodes (Caenorhabditis elegans), which can be used to compare the genetic similarities and differences in aging and regeneration strategies across species. Students will be fully integrated into the scientific culture of MDIBL through symposia, seminars, activities, responsible conduct of research training, and weekly career discussions. Students More information about the program is available in the NSF ETAP registration system and by visiting https://mdibl.org/education/student-fellowships/reu-summer-fellowships/, or by contacting the PI (Dr. Updike at dupdike@mdibl.org) or the co-PI (Dr. Disney at jdisney@mdibl.org).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
该REU SITE奖授予位于缅因州巴尔港的沙漠山岛生物实验室(MDIBL),将支持在2023-2025年夏季对10名学生进行为期10周的培训。预计共有30名学生将在该计划中接受培训,这些学生主要来自研究机会有限的学校或代表人数不足的群体。学生将处于本科学习的所有阶段,对显微镜和比较动物模型研究再生和衰老感兴趣的申请者将被特别考虑。学生将学习研究是如何进行的,许多人将在科学会议上展示他们的工作成果。将通过SALG Urssa在线工具对该方案进行评估。学生将被要求在NSF ETAP系统(etap.nsf.gov)注册,并在项目结束后进行跟踪,以确定他们的职业道路。这个REU项目MDIBL将使学生接触到用于了解再生和衰老生物学的比较动物模型方法。REU网站的实验室感兴趣的是细胞、组织、器官和四肢在受伤后或在正常发育过程中如何修复或补充,以及如何保留或重新使用机制,以确保有机体在发育完成后茁壮成长。为了回答这些问题,MDIBL的研究人员使用了各种动物模型。这些动物包括斑马鱼、剑鱼、紫杉醇、果蝇(果蝇)和线虫(线虫),这些动物可以用来比较不同物种在衰老和再生策略方面的遗传相似和差异。学生将通过研讨会、研讨会、活动、负责任的研究培训和每周的职业讨论,完全融入MDIBL的科学文化。学生可在美国国家科学基金会ETAP注册系统中获取更多有关该计划的信息,也可访问https://mdibl.org/education/student-fellowships/reu-summer-fellowships/,或联系国际组织(Updike博士邮箱:dupdike@mdibl.org)或联合国际组织(迪士尼博士邮箱:jdisney@mdibl.org)。该奖项反映了国家科学基金会的法定使命,并通过使用基金会的智力价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

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